Ureteric Jet Doppler Waveforms in Patients With Spinal Cord Injury

NCT05568862 | Completed

• 1 other identifier: ik
• Study Type: observational
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

Urinary dysfunction is very common in individuals with spinal cord injury. The urine flowing from the collecting ducts to the renal calyx stretches the calyces. ANS controlled peristaltic contractions originate in the proximal renal pelvis and travel down the ureters, pushing urine from the renal pelvis towards the bladder. The urine bolus delivered from the kidneys through the peristaltic contraction of the ureter creates an image called ureteric jet. Using the Doppler analysis of ureteral jets, previous studies have examined the changes in the ureteric jet pattern in pathological conditions such as the diagnosis of normal ureteral physiology.

Conditions

Spinal Cord Injuries

Outcome Measures

Primary Outcomes (2)

• doppler USG

  The patients included in the study group were given 600 cc of water in the morning and the Doppler USG was performed 30 minutes later

  15-30 minute

• Urodynamic assessment.

  A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit

  30 minute

Study Arms (2)

spinal cord injury

patient with spinal cord injury

Diagnostic Test: Doppler ultrasound, Urodynamic assessment.; Diagnostic Test: Urodynamic assessment.

no spinal cord injury

patient without spinal cord injury

Diagnostic Test: Doppler ultrasound, Urodynamic assessment.

Interventions

Doppler ultrasound, Urodynamic assessment. DIAGNOSTIC_TEST

The patients included in the study group were given 600 cc of water in the morning and the Doppler ultrasound was performed 30 minutes later

no spinal cord injury; spinal cord injury

Urodynamic assessment. DIAGNOSTIC_TEST

A transurethral double lumen catheter was used to measure intravesical pressure in the urodynamic unit for the patients in the study group immediately after the use of the Doppler USG

spinal cord injury

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Spinal cord injury patients who were hospitalized in the spinal cord injury Rehabilitation Unit of our rehabilitation center and 32 no spinal cord injury who presented at outpatient clinics.

You may qualify if:

• With signs of upper motor neuron lesion,
• Suprasacral spinal cord injury,
• Normal urinary ultrasound findings
• Planned urodynamics

You may not qualify if:

• Neurological disease other than spinal cord injury
• Urinary tract infection
• Urinary obstruction
• History of urinary tract Stones
• Diabetes, hypertension
• History of urinary surgery,
• Sacral injury
• Second motor neuron lesions (such as cauda equina, or cauda conus)
• The control group
• Normal urinary ultrasonography
• Neurological disease
• Urinary tract infection
• Urinary obstruction
• History of urinary tract Stones
• Diabetes, hypertension

Sponsors & Collaborators

• Gaziler Physical Medicine and Rehabilitation Education and Research Hospital: lead

Study Sites (1)

Gaziler PMR, Training and Research Hospital, Department of PMR

Ankara, Çankaya, 06100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Spinal Cord Injuries

Interventions

Ultrasonography, Doppler

Condition Hierarchy (Ancestors)

Spinal Cord Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Ultrasonography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• İlkay Karabay

  Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: October 1, 2022
• First Posted: October 6, 2022
• Study Start: June 17, 2021
• Primary Completion: March 20, 2022
• Study Completion: September 30, 2022
• Last Updated: October 7, 2022

Record last verified: 2022-10

Locations

TU (1)