NCT05567926

Brief Summary

This is a double-blind placebo-controlled cross-over trial that aims to determine the acute effect of beetroot juice ingestion on isometric knee extension strength, explosive strength and local muscular endurance.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2022

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

October 2, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 5, 2022

Completed
10 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 15, 2022

Completed
2 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 17, 2022

Completed
Last Updated

October 19, 2022

Status Verified

October 1, 2022

Enrollment Period

14 days

First QC Date

October 2, 2022

Last Update Submit

October 17, 2022

Conditions

Keywords

isometric strengthbeetrootnitrateslocal muscle endurancesupplementation

Outcome Measures

Primary Outcomes (1)

  • Knee extension strength

    The peak force during maximal voluntary contraction of knee extensors

    2 hours after the ingestion of beetroot juice or placebo

Secondary Outcomes (2)

  • Knee extension explosive strength

    2 hours after the ingestion of beetroot juice or placebo

  • Knee extension local muscle endurance

    2 hours after the ingestion of beetroot juice or placebo

Study Arms (2)

Experimental condition, receiving beetroot juice supplement

EXPERIMENTAL

Participants will receive beetroot juice intervention in the experimental condition.

Dietary Supplement: Beetroot juice concentrate (140 ml)

Placebo condition

PLACEBO COMPARATOR

Participants will receive placebo (blackcurrant juice) in the placebo condition

Dietary Supplement: Blackcurrant juice (placebo)

Interventions

A beetroot juice concentrate (140 ml) will be administered to participants in experimental conditions.

Experimental condition, receiving beetroot juice supplement

140 ml of blackcurrant juice with added appropriate amount of sugar to equalize the carbohydrate value and lemon juice fort the taste.

Placebo condition

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Age between 18 and 30 years
  • Physically active and healthy athletes (recreational or professional)

You may not qualify if:

  • Cardiovascular, pulmonary, metabolic, neurological diseases and musculoskeletal injuries
  • Smokers
  • Consumption of drugs such as antacids and proton pump inhibitors in the previous 3 months
  • Pregnant or breastfeeding women
  • Beetroot allergic participants

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Primorska Faculty of Health Sciences

Izola, SI-6310, Slovenia

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 2, 2022

First Posted

October 5, 2022

Study Start

October 1, 2022

Primary Completion

October 15, 2022

Study Completion

October 17, 2022

Last Updated

October 19, 2022

Record last verified: 2022-10

Locations