NCT05566496

Brief Summary

The findings of resting-state functional magnetic resonance imaging and diffusion spectrum imaging in subtypes of tics-related disorders

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
56mo left

Started Oct 2015

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress70%
Oct 2015Dec 2030

Study Start

First participant enrolled

October 20, 2015

Completed
7 years until next milestone

First Submitted

Initial submission to the registry

September 30, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 4, 2022

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2025

Completed
5.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2030

Expected
Last Updated

August 6, 2024

Status Verified

August 1, 2024

Enrollment Period

9.8 years

First QC Date

September 30, 2022

Last Update Submit

August 5, 2024

Conditions

Keywords

MRIpediatric neurology

Outcome Measures

Primary Outcomes (1)

  • Difference between healthy and Tourette group

    Difference of MRI result between healthy and Tourette group

    2 years after enrollment for primary evaluation

Study Arms (2)

Tourette

Age less than 18 years old Diagnosed as Tourette syndrome or chronic tic disorders No other neuropsychiatric disorders

Diagnostic Test: Brain MRI

Healthy

Age less than 18 years old No other neuropsychiatric disorders

Diagnostic Test: Brain MRI

Interventions

Brain MRIDIAGNOSTIC_TEST

All participants receive brain MRI evaluation and clinical evaluation of tic severity.

HealthyTourette

Eligibility Criteria

Age0 Years - 18 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

We enrolled treatment-naive Tourette syndrome or chronic tic disorder pediatric patients for Tourette group and healthy age- and gender-matched participants for healthy control

You may qualify if:

  • Age less than 18 years old
  • Diagnosed as Tourette syndrome or chronic tic disorders

You may not qualify if:

  • History of neuropsychiatric disorders
  • Already receive treatment for Tourette syndrome/chronic tics disorder
  • Have some device not allowed for MRI scan

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan University Children Hospital Pediatric Neurology Department

Taipei, 100, Taiwan

RECRUITING

Study Officials

  • Wang-Tso Lee

    National Taiwan University Children Hospital Pediatric neurology department

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 30, 2022

First Posted

October 4, 2022

Study Start

October 20, 2015

Primary Completion

August 1, 2025

Study Completion (Estimated)

December 1, 2030

Last Updated

August 6, 2024

Record last verified: 2024-08

Locations