NCT05566249

Brief Summary

This study is to validate the safety and feasibility of ArtiSential (Articulating laparoscopic instrument) colorectal surgery and compare it with robotic surgery for patients with rectal cancer and rectosigmoid junction cancer.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
44mo left

Started Oct 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress50%
Oct 2022Dec 2029

First Submitted

Initial submission to the registry

September 28, 2022

Completed
3 days until next milestone

Study Start

First participant enrolled

October 1, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 4, 2022

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2029

Expected
Last Updated

October 6, 2022

Status Verified

October 1, 2022

Enrollment Period

2.3 years

First QC Date

September 28, 2022

Last Update Submit

October 4, 2022

Conditions

Keywords

laparoscopic surgeryminimally invasive surgeryrobotic-assisted surgeryrobotic surgeryDa Vinci systemArtiSentialArticulating laparoscopic instrument

Outcome Measures

Primary Outcomes (2)

  • Surgical failure

    conversion, postoperative complications, or less than 12 harvested lymph nodes

    1 month

  • Cost

    Total medical cost during hospital stay for surgery

    1 month

Secondary Outcomes (2)

  • Oncologic outcomes

    5-year

  • Oncologic outcomes

    5-year

Study Arms (2)

ArtiSential group

Patients undergoing laparoscopic surgery using ArtiSential

Device: ArtiSential

Robot group

Patients undergoing robotic surgery

Interventions

Articulating laparoscopic instrument

ArtiSential group

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The patients with rectal or rectosigmoid junction adenocarcinoma who will be planned to undergo elective low anterior resection with double stapled technique.

You may qualify if:

  • Age : 18 \~ 80 year old male or female
  • Biopsy-proven adenocarcinoma
  • Rectal cancer or Rectosigmoid junction cancer
  • Primary cancer
  • Non-metastatic cancer
  • Planned (or elective) curative resection
  • Low anterior resection with double-stapled technique

You may not qualify if:

  • Preoperative systemic chemotherapy
  • Distant metastasis at initial diagnosis
  • Palliative surgery
  • Emergent surgery
  • Lynch syndrome or FAP-associated cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Samsung Medical Center

Seoul, South Korea

RECRUITING

Related Publications (1)

  • Pyo DH, Kim S, Do M, Huh JW. Laparoscopic Ultralow Anterior Resection Using a New Articulating Device. Dis Colon Rectum. 2025 Jan 1;68(1):e5. doi: 10.1097/DCR.0000000000003287. Epub 2024 Sep 12. No abstract available.

MeSH Terms

Conditions

Rectal Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesIntestinal DiseasesRectal Diseases

Central Study Contacts

Jung Wook Huh, MD PhD

CONTACT

Dae HEe Pyo, MD PhD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 28, 2022

First Posted

October 4, 2022

Study Start

October 1, 2022

Primary Completion

December 31, 2024

Study Completion (Estimated)

December 31, 2029

Last Updated

October 6, 2022

Record last verified: 2022-10

Locations