Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Analgesia in Inguinal Hernia Repair
Ultrasound-guided Transversalis Fascia Plane Block Versus Erector Spinae Plane Block for Post-operative Analgesia in Inguinal Hernia Repair Under General Anesthesia: a Randomized Controlled Study
1 other identifier
interventional
43
1 country
1
Brief Summary
Uncontrolled postoperative pain after inguinal hernia repair increases the incidence of postoperative complications.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Dec 2022
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 30, 2022
CompletedFirst Posted
Study publicly available on registry
October 4, 2022
CompletedStudy Start
First participant enrolled
December 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 31, 2025
CompletedMarch 17, 2026
March 1, 2026
2.8 years
September 30, 2022
March 14, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
The intensity of postoperative pain
Assessed by the verbal analog pain scale graded from 0 to 10 (0 = no pain, and 10 = the worst possible pain)
24 hours after surgery
Study Arms (2)
Transversalis fascia plane (TFP) block
PLACEBO COMPARATORPatients will receive unilateral US-TFP block with bupivacaine 15 minutes before skin incision
Erector Spinae Plane (ESP) Block
ACTIVE COMPARATORPatients will receive unilateral US-ESP block with bupivacaine 15 minutes before skin incision
Interventions
Patients will receive unilateral US-ESP block with 0.3 mL/kg bupivacaine 0.25% 15 minutes before skin incision
Patients will receive unilateral US-TFP block with 0.3 mL/kg bupivacaine 0.25% 15 minutes before skin incision
Eligibility Criteria
You may qualify if:
- Male patients undergoing elective open unilateral inguinal hernia repair under general anesthesia, ASA status I-II, aged from 20 to 65 years old
You may not qualify if:
- Contraindications to regional block (coagulopathy, infection at the needle insertion site, or diaphragmatic paralysis)
- Altered cognitive function
- Body mass index (BMI \> 35 kg/m2)
- Patients who have difficulty understanding the study protocol
- Patients who have any known allergy to study medications
- Advanced hepatic or renal failure
- Chronic opioid consumption
- Patient refusal
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Assiut University
Asyut, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant professor of Anesthesia and Intensive Care
Study Record Dates
First Submitted
September 30, 2022
First Posted
October 4, 2022
Study Start
December 1, 2022
Primary Completion
August 31, 2025
Study Completion
August 31, 2025
Last Updated
March 17, 2026
Record last verified: 2026-03