Optical Coherence Tomography Angiography Criteria Of The Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia (Comparative Study).

NCT05562336 | Unknown

• 1 other identifier: Soh-Med-22-09-03
• Study Type: observational
• Target: 2
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study aims to compare choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia.

Conditions

Choroidal Neovascular Membrane In Wet Age Related Macular Degeneration And In Pathological Myopia

Outcome Measures

Primary Outcomes (1)

• choroidal neo-vascular membrane criteria in cases of age-related macular degeneration and cases of pathological myopia

  choroidal neo-vascular membrane identified by Optical Coherence Tomography Angiography

  through study completion, an average of 1 year

Study Arms (2)

Patients with age related macular degeneration with CNV

Device: Optical coherence tomography angiography

Patients with pathological myopia with CNV

Device: Optical coherence tomography angiography

Interventions

Optical coherence tomography angiography DEVICE

Optical coherence tomography (OCT) is a noninvasive imaging method that uses reflected light to create pictures of the back of your eye

Patients with age related macular degeneration with CNV; Patients with pathological myopia with CNV

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Cnv in age related macular degeneration and in pathological myopia

You may qualify if:

• Patients with age related macular degeneration should be at least 50 years of age with CNV with no other causes.
• Patients with pathological myopia where axial length more than 26 mm or refractive power more than -6 diopter with CNV in OCT with clear media and OCT-angio can be used.

You may not qualify if:

• Exclude other pathological causes of CNV .

Sponsors & Collaborators

• Sohag University: lead

Related Publications (4)

• Hee MR, Baumal CR, Puliafito CA, Duker JS, Reichel E, Wilkins JR, Coker JG, Schuman JS, Swanson EA, Fujimoto JG. Optical coherence tomography of age-related macular degeneration and choroidal neovascularization. Ophthalmology. 1996 Aug;103(8):1260-70. doi: 10.1016/s0161-6420(96)30512-5.

  PMID: 8764797 BACKGROUND

• Secretan M, Kuhn D, Soubrane G, Coscas G. Long-term visual outcome of choroidal neovascularization in pathologic myopia: natural history and laser treatment. Eur J Ophthalmol. 1997 Oct-Dec;7(4):307-16. doi: 10.1177/112067219700700401.

  PMID: 9457451 BACKGROUND

• Miller DG, Singerman LJ. Vision loss in younger patients: a review of choroidal neovascularization. Optom Vis Sci. 2006 May;83(5):316-25. doi: 10.1097/01.opx.0000216019.88256.eb.

  PMID: 16699445 BACKGROUND

• Kovach JL, Schwartz SG, Flynn HW Jr, Scott IU. Anti-VEGF Treatment Strategies for Wet AMD. J Ophthalmol. 2012;2012:786870. doi: 10.1155/2012/786870. Epub 2012 Feb 28.

  PMID: 22523653 BACKGROUND

Central Study Contacts

Arwa El-shabrakhity

CONTACT

0111 462 4205; arwa_mohamed@med.sohag.edu.eg

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 22, 2022
• First Posted: September 30, 2022
• Study Start: October 1, 2022
• Primary Completion: November 1, 2023
• Study Completion: December 1, 2023
• Last Updated: September 30, 2022

Record last verified: 2022-09