OCTA Study: Retinal Vascular Changes in Patients With SARS-CoV-2 Infection
Optical Coherence Tomography Angiography in Patients Affected by SARS-CoV-2 Infection: a Pilot Study
1 other identifier
observational
40
1 country
1
Brief Summary
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that have been affected by COVID-19.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Sep 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 20, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 20, 2020
CompletedFirst Submitted
Initial submission to the registry
October 22, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
October 22, 2020
CompletedFirst Posted
Study publicly available on registry
October 23, 2020
CompletedJanuary 19, 2021
October 1, 2020
1 month
October 22, 2020
January 14, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
The measurements of retinal features in patients with previous diagnosis of COVID19, using optical coherence tomography angiography.
The parameter analyzed by optical coherence tomography angiography was: retinal vessel density
one month
Study Arms (2)
Patients with COVID19
The patients with previous diagnosis of COVID19
Control subjects
Healthy subjects without actual and previous ocular diseases
Interventions
Each subject underwent optical coherence tomography angiography to evaluate the retinal vessel density.
Eligibility Criteria
The participans were older than 18 years with previous diagnosis of COVID-19. They did not present other ophthalmological diseases.
You may qualify if:
- age older than 18 years
- diagnosis of previous COVID-19
- absence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
- absence of significant lens opacities, low-quality OCT and OCT-A images.
You may not qualify if:
- age younger than 18 years
- absence of previous diagnosis of COVID-19
- presence of previous ocular surgery, congenital eye disease, high myopia (\>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
- presence of significant lens opacities, low-quality OCT and OCT-A images.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Naples "Federico II"
Naples, 80100, Italy
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Gilda Cennamo
Federico II University
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
October 22, 2020
First Posted
October 23, 2020
Study Start
September 20, 2020
Primary Completion
October 20, 2020
Study Completion
October 22, 2020
Last Updated
January 19, 2021
Record last verified: 2020-10