Axial Length With Adult Onset Myopia (ALWAOM)
ALWAOM
1 other identifier
interventional
100
1 country
1
Brief Summary
Purpose: To determine axial length progression and its relationship with myopia onset and progression in adults.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2023
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 26, 2022
CompletedFirst Posted
Study publicly available on registry
September 29, 2022
CompletedStudy Start
First participant enrolled
September 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2025
CompletedAugust 6, 2024
August 1, 2024
1.7 years
September 26, 2022
August 5, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Axial Length progression
The change in the length of the eye from the anterior cornea to the retina over time
Two years
Effect of Orthokeratology on axial length changes
Compare the average axial length changes of subjects wearing orthokeratology lenses to those who do not
Two years
Study Arms (1)
Orthokeratology
OTHEROrthokeratology is fitting of a contact lens for overnight wear to flatten the cornea and correct myopia temporarily during the day. This procedure has also been shown to slow down the axial length growth in children.
Interventions
The use of a specialty GP contact lens to temporarily correct myopia
Eligibility Criteria
You may qualify if:
- st year optometry student
- Refractive error - spherical Component: +2.00D to -5.00D; astigmatic Component: up to -1.50D; non-presbyopic
- Not currently using any treatment for myopia control, including Orthokeratology lenses, soft multifocal lenses, MiSight lenses, pharmacological interventions, or spectacles for myopia control
- No significant anterior or posterior segment disease
You may not qualify if:
- Non-graduate student
- Refractive error outside of: +2.00D to -5.00D; astigmatic Component: up to -1.50D; presbyopic
- Any participants using treatment for myopia control, including Orthokeratology lenses, soft multifocal lenses, MiSight lenses, pharmacological interventions, or spectacles for myopia control
- Significant anterior or posterior segment disease
- Pregnancy
- Significant systemic disease that may affect refractive error (i.e. diabetes)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Art Optical Contact Lens, Inc.lead
- University of Missouri, St. Louiscollaborator
Study Sites (1)
University of Missouri-St. Louis College of Optometry
St Louis, Missouri, 63121, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 26, 2022
First Posted
September 29, 2022
Study Start
September 1, 2023
Primary Completion
May 1, 2025
Study Completion
August 1, 2025
Last Updated
August 6, 2024
Record last verified: 2024-08
Data Sharing
- IPD Sharing
- Will not share