NCT05546008

Brief Summary

  1. 1.Assesment of pediatric CHD by Echocardiography and Multislice CT before operation and compare with surgical results.
  2. 2.Compare echocardiogram and 128-Multislice spiral computed tomography(MSCT) in the diagnosis of pediatric CHD.
  3. 3.Confirm echocardiographic finding in pediatric CHD by(MSCT) and to show the role of MSCT in diagnosing of extra-cardia anomalies.
  4. 4.to show the role of MSCT as a useful tool in defintive diagnosis of congenital heart disease before operations which assist surgeons

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2022

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 10, 2022

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 10, 2022

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

September 15, 2022

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 19, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 10, 2022

Completed
Last Updated

September 19, 2022

Status Verified

September 1, 2022

Enrollment Period

Same day

First QC Date

September 15, 2022

Last Update Submit

September 15, 2022

Conditions

Congenital Heart Disease

Outcome Measures

Primary Outcomes (1)

  • comparison between Multislice CT and Echo cardiography in diagnosis of congenital heart disease

    The study will be conducted at Assiut University Children Hospital from septemper 2022 to septemper 2023 on children with congenital heart disease 1-Echocardiography ECHO will be performed using the Diamond Select iE33 Ultrasound system (Philips Medical Systems, Netherlands)(6) 2-128-MSCT Patients will be given oral chloral hydrate solution with a dosage of 50 mg/kg. The 64-MSCT examination will be performed by SOMATOM Perspective

    baseline

Interventions

Multislice CTDEVICE

all patient will be subjected to echocardigraphy and multislice ct and compare thier results

Also known as: Echocardiography

Eligibility Criteria

Age0 Years - 18 Years
Sexall(Gender-based eligibility)
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

children with congenital heart disease less than 18years

You may qualify if:

  • children with congenital heart disease less than 18years

You may not qualify if:

  • Children with congenital heart disease \>18 years.
  • Children suffering from renal disease .
  • Children with non-sinus rhythm .
  • Children who are allergic to iodinated contrast media .

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (6)

  • VANPRAAGH R, VANPRAAGH S, VLAD P, KEITH JD. ANATOMIC TYPES OF CONGENITAL DEXTROCARDIA: DIAGNOSTIC AND EMBRYOLOGIC IMPLICATIONS. Am J Cardiol. 1964 Apr;13:510-31. doi: 10.1016/0002-9149(64)90159-6. No abstract available.

    PMID: 14136294BACKGROUND

  • Alakhfash AA, Tamimi OR, Al-Khattabi AM, Najm HK. Treatment options for transposition of the great arteries with ventricular septal defect complicated by pulmonary vascular obstructive disease. J Saudi Heart Assoc. 2009 Jul;21(3):187-90. doi: 10.1016/j.jsha.2009.06.008. Epub 2009 Aug 5.

    PMID: 23960571BACKGROUND

  • Pasquini L, Sanders SP, Parness I, Colan S, Keane JF, Mayer JE Jr, Kratz C, Foran RB, Marino B, Van Praagh S, et al. Echocardiographic and anatomic findings in atrioventricular discordance with ventriculoarterial concordance. Am J Cardiol. 1988 Dec 1;62(17):1256-62. doi: 10.1016/0002-9149(88)90270-6.

    PMID: 3195487BACKGROUND

  • Wang XM, Wu LB, Sun C, Liu C, Chao BT, Han B, Zhang YT, Chen HS, Li ZJ. Clinical application of 64-slice spiral CT in the diagnosis of the Tetralogy of Fallot. Eur J Radiol. 2007 Nov;64(2):296-301. doi: 10.1016/j.ejrad.2007.02.026. Epub 2007 Mar 30.

    PMID: 17399932BACKGROUND

  • Liu H, Juan YH, Chen J, Xie Z, Wang Q, Zhang X, Liang C, Huang H, Kwong RY, Saboo SS. Anomalous Origin of One Pulmonary Artery Branch From the Aorta: Role of MDCT Angiography. AJR Am J Roentgenol. 2015 May;204(5):979-87. doi: 10.2214/AJR.14.12730.

    PMID: 25905931BACKGROUND

  • Watts JR Jr, Sonavane SK, Nath PH, Singh SP. Pictorial review of the role of multidetector computed tomography imaging in the postoperative evaluation of congenital heart disease. Curr Probl Diagn Radiol. 2014 Jul-Aug;43(4):205-18. doi: 10.1067/j.cpradiol.2014.04.001.

    PMID: 24948213BACKGROUND

MeSH Terms

Conditions

Heart Defects, Congenital

Interventions

Echocardiography

Condition Hierarchy (Ancestors)

Cardiovascular AbnormalitiesCardiovascular DiseasesHeart DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Cardiac Imaging TechniquesDiagnostic ImagingDiagnostic Techniques and ProceduresDiagnosisUltrasonographyHeart Function TestsDiagnostic Techniques, Cardiovascular

Central Study Contacts

mohamed bahaa

CONTACT

01095444351bahaamohmed054@gmail.com

Doaa Raafat

CONTACT

0107934347Doaa-rafat2010@gmail.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
DR

Study Record Dates

First Submitted

September 15, 2022

First Posted

September 19, 2022

Study Start

September 10, 2022

Primary Completion

September 10, 2022

Study Completion

November 10, 2022

Last Updated

September 19, 2022

Record last verified: 2022-09