The Role of Multislice Computed Tomography in Congenital Heart Diseases in Paediatric Age Group.

NCT06223321 | Unknown

• 1 other identifier: Soh-Med-23-12-02MD
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the added value of cardiac multislice Computed Tomography in assessment of CHD in pediatrics as a non-invasive presurgical planning method

Conditions

Congenital Heart Diseases

Keywords

Computed Tomography - congenital heart diseases

Outcome Measures

Primary Outcomes (1)

• Multislice Computed Tomography in congenital heart diseases in Paediatric age group

  added value of cardiac multislice Computed Tomography in assessment of CHD in pediatrics as a non-invasive presurgical planning method (detection of other lesion not seen by other imaging modalities )

  within one week after Computed Tomography done

Interventions

Computed Tomography in congenital heart diseases DIAGNOSTIC_TEST

● CT examination will be done by * 160 MDCT Toshiba Machine or 128 MDCT GE machine or 160 MDCT Philips Machine: * We used the following parameters during cardiac CT scanning: * Pitch of 1.3, helical thickness of 0.5 mm and coverage of 32 cm. * The radiation dose set to 80-100 kvp. * Tube current from 10 to 40 mA/kg. * The gantry rotation speed at 0.35-.4 sec. * ECG gated Retrospective With MA modulation. * Wide FOV. * A scout will be taken and dual-phase injection conducted using non ionized contrast material. The total contrast volume is 1.5-3 ml/kg. * Scanning begins when contrast filled the LV by bolus tracking. * All images were transferred to workstation multiplanar reformation (MPR), maximum (MIP) and minimum (MinIP) intensity projections and volume rendering images will be performed for reporting.

Eligibility Criteria

• Age: 1 Day - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

* All children gave an informed consent prior performing the research. * Every child was submitted to full history taking. * Clinical assessment of the patients will be performed in the form of: measuring of vital signs and anthropometric measurements. * Renal function tests(ѕerum creatinine and blood urea).

You may qualify if:

• Patients suspected to have congenital heart disease based on clinical findings.
• Patients known to have congenital heart diseased based on echocardiography (ECHO) with ECHO findings are not sufficient and referred to perform CT for further assessment

You may not qualify if:

• Post-operative Patients of congenital heart disease.
• Patients who are known to have hyper susceptibility to iodinated Contrast media reaction, impaired renal functions, respiratory failure, fever and severe asthma and patients with arrhythmia.

Sponsors & Collaborators

• Sohag University: lead
• Magdi Yacoub Heart Foundation: collaborator

Study Sites (1)

Sohag university hospitals- faculity of medicine

Sohag, Egypt

Location

MeSH Terms

Conditions

Heart Defects, Congenital

Interventions

Tomography, X-Ray Computed

Condition Hierarchy (Ancestors)

Cardiovascular Abnormalities; Cardiovascular Diseases; Heart Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Image Interpretation, Computer-Assisted; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Radiographic Image Enhancement; Image Enhancement; Photography; Radiography; Tomography, X-Ray; Tomography

Study Officials

• Mohamed AA Elsherif, ASSISST. LEC

  Sohag University Hospitals

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: ASSISTANT LECTURE AT DIAGNOSTIC AND INTERVENTIONAL RADIOLOGY DEPARTMENT

Study Record Dates

• First Submitted: January 2, 2024
• First Posted: January 25, 2024
• Study Start: January 3, 2023
• Primary Completion: June 1, 2024
• Study Completion: December 1, 2024
• Last Updated: January 25, 2024

Record last verified: 2024-01

Locations

EG (1)