Diagnostic Performance of Coronary Calcification Detection on CT Scan

NCT05538117 | Completed

• 1 other identifier: 8697
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

thoracic pain is one of the most frequent reasons for consulting the emergency room. Chest pain can be a sign of different pathologies with a wide range of severity, from life-threatening aortic dissection or myocardial infarction to chest pain during an anxiety attack. Efficient triage of patients is therefore a crucial issue for emergency physicians in order not to ignore an acute coronary event requiring early and specific management. The investigators seek to evaluate whether a diagnostic strategy based on a thoracic CT scan to rule out coronary calcifications and a single troponin assay can exclude an acute coronary event with sufficient accuracy compared to usual management.

Conditions

Acute Coronary Syndrome

Keywords

Thoracic pain; Acute coronary event; CT scan; Thoracic scan; Coronary calcifications; Acute Coronary Syndrome

Outcome Measures

Primary Outcomes (1)

• Ability of scan CT to detect coronary calcifications in patients presenting with thoracic pain to the emergency department

  Presence on the scanner of calcifications 30 minutes after onset of pain

  30 minutes after onset of pain

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patient (≥18 years old) admitted to the emergency room of the Nouvel Hôpital Civil in Strasbourg between 06/01/2021 and 12/31/2021 and presenting with typical chest pain \<30min or atypical symptoms but non-eliminable cardiac origin.

You may qualify if:

• Adult patient (≥18 years old)
• Patient admitted to the emergency room of the Nouvel Hôpital Civil in Strasbourg between 06/01/2021 and 12/31/2021 and presenting with typical chest pain \<30min or atypical symptoms but non-eliminable cardiac origin.
• Patient with an initial assessment within the norms (ECG not modified, first troponin negative) and having performed a chest CT scan
• Patient who has not expressed his opposition to the reuse of his data for scientific research purposes.

You may not qualify if:

• \- Patient who has expressed his opposition to the retrospective reuse of his data for scientific research purposes

Sponsors & Collaborators

• University Hospital, Strasbourg, France: lead

Study Sites (1)

Service d'accueil des urgences - CHU de Strasbourg - France

Strasbourg, 67091, France

Location

MeSH Terms

Conditions

Acute Coronary Syndrome; Chest Pain

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 8, 2022
• First Posted: September 13, 2022
• Study Start: August 18, 2022
• Primary Completion: August 18, 2023
• Study Completion: October 18, 2023
• Last Updated: December 13, 2023

Record last verified: 2023-12

Locations

FR (1)