Symptoms of Acute Coronary Syndrome in Medical Regulation

NCT05902130 | Completed

• 1 other identifier: 2023-03Obs-CHRMT
• Study Type: observational
• Target: 208
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective was to analyze the impact of the gender of the attending physician in the differences in the management of ST+ ACS between men and women. This study will be conducted in partnership with the interventional cardiology team of the CHR Metz-Thionville and SAMU (emergency call center) of Moselle, which has a detailed registry of coronary angiographies at the center. A retrospective observational study will be carried out over a "typical" period outside of covid at the CHR Metz Mercy (2021-2022) based on coronary angiographies performed in the context of ST+ ACS at the CHR of patients referred by the center 15. The patient's medical record will be analyzed, going back to his call to the 15 via tape listening. The number of subjects required being calculated at 104 men and 104 women, these patients will be selected from the database of our cardiologist colleagues and we will match one man to one woman by comparing the delays of several items (1st medical contact, time of 1st ECG, medicalization or not, delay of call to the cardiologist, delay of coronary angiography...) according to the sex of the regulator. The consequences of a difference in management will be also evaluated by analyzing in-hospital mortality, mortality at 30 days of management, and functional sequelae at discharge (grades of dyspnea, disturbance of myocardial contractility, LVEF at discharge). This study based on the differences in questioning according to the gender of the regulating physician would allow better identification of the factors that increase the delay in the management of ST+ ACS in women, and to find avenues of correction in order to limit the loss of opportunity for patients. The patients included who are still alive will receive a notification of non-objection by mail.

Conditions

Acute Coronary Syndrome

Keywords

acute coronary syndrome; out-hospital care; medical regulation

Outcome Measures

Primary Outcomes (1)

• Delay between the call to the emergency center and the first contact with a physician

  Delay (minutes:seconds)

  End of the call to the emergency center, less than 10 min

Secondary Outcomes (6)

• Delay between the call to the emergency center and the first electrocardiogram

  At hospital discharge, an average of 2 hours

• Dispatch of a medical ambulance (Y/N)

  End of the call to the emergency center, an average of 20 min

• Delay between the call to the emergency center and the first coronary angiography

  At hospital discharge, an average of 2 hours

• In-hospital mortality

  30 days after the call to emergency center

• Day 30 mortality

  30 days after the call to emergency center

Interventions

symptoms of a myocardial infarction OTHER

Analysis of the differences in symptoms of a myocardial infarction between a man and a woman

Eligibility Criteria

• Age: 18 Years+
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The cohort includes patients admitted for coronary angiography at the Mercy hospital center in 2021-2022, having had a confirmed diagnosis of ACS ST+ and who made an initial call to the Moselle SAMU.

You may qualify if:

• patient with emergency coronary angiography for ST+ ACS
• having made a call to the Emergency Center for the same reason

You may not qualify if:

• non-real ST+ ACS

Sponsors & Collaborators

• Centre Hospitalier Régional Metz-Thionville: lead

Study Sites (1)

CHR Metz-Thionville/Hopital de Mercy

Metz, 57085, France

Location

MeSH Terms

Conditions

Acute Coronary Syndrome

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Study Officials

• Laure ABENSUR VUILLAUME, MD, PhD

  CHR Metz Thionville Hopital de Mercy

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 22, 2023
• First Posted: June 13, 2023
• Study Start: January 1, 2023
• Primary Completion: October 1, 2023
• Study Completion: October 1, 2023
• Last Updated: December 26, 2023

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)