Comparison Between the Quadratus Lumborum Block ,Erector Spinae Plane Block in Lower Abdominal Surgery

NCT05524038 | Completed DMC

• 1 other identifier: D237
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

the purpose of study is comparison between the analgesic effect of two techniques in adult lower abdominal surgeries

Conditions

Lower Abdominal Surgery

Keywords

Quadratus Lumborum; Erecto Spinae plane

Outcome Measures

Primary Outcomes (1)

• morphine consumption

  Millie gram

  24 hours after the end of operation

Secondary Outcomes (8)

• Ease of performance.

  during performance of the block

• Bowel injury

  24hours after operation

• intra vascular injection

  24hours after operation

• Hematoma formation

  24hours after operation

• Pruritus

  24hours after operation

Other Outcomes (10)

• time of first using of analgesic

  24 hours

• Visual Analogue Score immediately .

  1 minute post operative

• Visual Analogue Score at (4)

  4 hour post operative

Study Arms (2)

(QL) group

ACTIVE COMPARATOR

In (QL) group, (lateral Approach) :patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone

Drug: Bupivacaine Hydrochloride; Device: Ultrasound device; Drug: Dexamethasone; Device: echogenic needle

(ESB) group

ACTIVE COMPARATOR

In (ESB) group, Erector Spinae Plane Block: patient receive this block with 20 mg bupivacaine hydrochloride plus 4mg dexamethasone

Drug: Bupivacaine Hydrochloride; Device: Ultrasound device; Drug: Dexamethasone; Device: echogenic needle

Interventions

Bupivacaine Hydrochloride DRUG

20mg of Bupivacaine hydrochloride as local anesthetic will be used in (QL) group and (ESB) group

Also known as: Marcaine 0.25%

(ESB) group; (QL) group

Ultrasound device DEVICE

high-frequency linear probe covered with sterile sheath Active Array L12-4 (8-13MHz) of an ultrasound machine (Philips clear vue350, Philips Healthcare, Andover MA01810, USA) for performing the blocks .

(ESB) group; (QL) group

Dexamethasone DRUG

injection of 4mg dexamethasone in each block

Also known as: Dexamethasone 4mg/ml

(ESB) group; (QL) group

echogenic needle DEVICE

22- gauge, 50 mm echogenic needle (Stimuplex D; B Braun, Germany) for performing the blocks .

(ESB) group; (QL) group

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients age 18-60 years old.
• Patients scheduled for elective abdominal surgeries
• ASA classification I, II.
• Ability to sign the consent.

You may not qualify if:

• Patient refusal.
• Coagulation disorders.
• Skin lesions or infection at site of proposed needle.
• Known allergy to local anesthetics, or opioids.
• Patients suffering from neurological or mental disease.
• Opioid consumption 48 hours before the operation.
• Sever Obesity body mass index(BMI) \>35
• Difficulty in Ultrasonographic identification.

Sponsors & Collaborators

• Fayoum University Hospital: lead

Study Sites (1)

Fayoum University hospital

Al Fayyum, Fayoum Governorate, 63514, Egypt

Location

Related Publications (2)

• Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.

  PMID: 27501016 BACKGROUND

• El-Boghdadly K, Pawa A. The erector spinae plane block: plane and simple. Anaesthesia. 2017 Apr;72(4):434-438. doi: 10.1111/anae.13830. Epub 2017 Feb 11. No abstract available.

  PMID: 28188611 BACKGROUND

MeSH Terms

Interventions

Bupivacaine; Ultrasonography; Dexamethasone

Intervention Hierarchy (Ancestors)

Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Pregnadienetriols; Pregnadienes; Pregnanes; Steroids; Fused-Ring Compounds; Polycyclic Compounds; Steroids, Fluorinated

Study Officials

• rana A. Abdelghaffar, MD

  faculty of medicine ,Fayum university

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Masking Details: Randomization will be done by random sequence number generated by the computer kept in sealed envelopes. Those envelopes will be opened on the day of surgery when the patient is in the operating room and participant will receive either (QLB) or (ESPB) as per the envelope.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: lecturer of anesthesiology

Model Details: 1. (QL) QLB group 2. (ESB) group

Study Record Dates

• First Submitted: August 29, 2022
• First Posted: September 1, 2022
• Study Start: September 1, 2021
• Primary Completion: May 1, 2024
• Study Completion: February 1, 2025
• Last Updated: August 20, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)