NCT05517824

Brief Summary

The investigators aimed to evaluate the efficacy and safety of a fractional radiofrequency device with a micro-insulated needle to reduce submental fat.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 7, 2021

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2021

Completed
3 days until next milestone

Study Completion

Last participant's last visit for all outcomes

November 4, 2021

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

August 23, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 26, 2022

Completed
Last Updated

August 26, 2022

Status Verified

August 1, 2022

Enrollment Period

5 months

First QC Date

August 23, 2022

Last Update Submit

August 24, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Physician-Assisted Submental Fat Rating Scale score from 0 (nothing) to 4 (very severe)

    submental fat rating by an independent investigator

    1 month after the treatment

Secondary Outcomes (3)

  • submental fat volume (cc)

    1 month after the treatment

  • patient satisfaction score from 0 (not satisfied) to 10 (most satisfied)

    1 month after the treatment

  • any adverse effects at any time during or after treatment

    assessed through study completion, an average of 2 months

Study Arms (2)

Post-treatment

ACTIVE COMPARATOR

After a single treatment using a microinsulated needle RF device

Procedure: microinsulated needle radiofrequency

Pre-treatment (Baseline)

NO INTERVENTION

Interventions

A single treatment using a microinsulated needle radiofrequency device

Post-treatment

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with excess submental fat on a grade of 1\~4, as assessed by the Physician-Assisted Submental Fat Rating Scale

You may not qualify if:

  • mental impairment, infectious disease
  • history of keloid development
  • pregnancy, pacemaker
  • use of anticoagulants
  • undergoing a facelift procedure within the prior 6 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Seoul National University Bundang Hospital

Seongnam, 13620, South Korea

Location

Related Publications (1)

  • Kim BR, Kim M, Kim JW, Shin JW, Na JI, Huh CH. Efficacy and Safety of the Micro-insulated Needle Radiofrequency Device for Reduction of Submental Fat. Dermatol Surg. 2023 Apr 1;49(4):389-394. doi: 10.1097/DSS.0000000000003723. Epub 2023 Feb 10.

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Chang-Hun Huh

    Seoul National University Bundang Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SEQUENTIAL
Model Details: prospective, single-blinded, pre-post comparative study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

August 23, 2022

First Posted

August 26, 2022

Study Start

June 7, 2021

Primary Completion

November 1, 2021

Study Completion

November 4, 2021

Last Updated

August 26, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

Locations