Swiss Secondary Prevention and Rehabilitation Registry

NCT05500859 | Recruiting

• 1 other identifier: 2019-02057; me19Pfister
• Study Type: observational
• Target: 4,000
• Locations: 1 country
• Sites: 1

Brief Summary

The SwissPR study is to continuously monitor patient characteristics and short- and long-term benchmark quality measures and outcomes of patients participating in a 12-week ambulatory CR program.

Conditions

Cardiovascular Diseases (CVD)

Keywords

Coronary artery disease (CAD); Cardiac rehabilitation (CR); Acute coronary syndrome (ACS); Chronic coronary syndrome (CCS); Prevention benchmark performance measures (BPM); KARAMBA; Swiss Prevention and Rehabilitation Registry (SwissPR)

Outcome Measures

Primary Outcomes (5)

• Change in Guideline recommended medical therapy

  Change in Guideline recommended medical therapy (Guideline recommended medical therapy is one variable in predefined secondary prevention benchmark performance measures (BPM) at one year after CR)

  1 year

• Change in predefined secondary prevention benchmark performance measures (BPM) at one year after CR: LDL-Cholesterol target value

  Change in predefined secondary prevention benchmark performance measures (BPM) at one year after CR: LDL-Cholesterol target value

  1 year

• Change in predefined secondary prevention benchmark performance measures (BPM) at one year after CR: blood-pressure (systolic and diastolic)

  Change in predefined secondary prevention benchmark performance measures (BPM) at one year after CR: Achievement of target blood-pressure

  1 year

• Change in smoking status

  Change in smoking status (smoking status is a predefined secondary prevention benchmark performance measures (BPM) at one year after CR: Achievement of Non-smoking status)

  1 year

• Change in predefined secondary prevention benchmark performance measures (BPM) at one year after CR: exercise/ week

  Change in predefined secondary prevention benchmark performance measures (BPM) at one year after CR: Achievement of 150 minutes of exercise/ week (self-reported)

  1 year

Secondary Outcomes (7)

• Percentage of patients reaching the predefined secondary prevention benchmark after CR

  3 months after baseline

• Change in physical activity

  up to 5 years

• Change in medical therapy between visits

  up to 5 years

• Change in quality of life questionnaire/ score between visits

  up to 5 years

• Change in Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention (TRS 2P) between visits

  up to 5 years

Interventions

Data collection at Baseline, 3 months after baseline (BL), 1-year follow-up, Telephone follow-up and questionnaire 3 years and 5 years after BL OTHER

Data collection (Patient characteristics including medical history, current medication, cardiovascular risk factors, routine laboratory analysis (including lipids, Hb1c, NT-proBNP), clinical status, electrocardiogram, echocardiography data from latest echo, cardio pulmonary exercise testing (CPET), questions on general health behavior (diet, weekly exercise load), Quality of Life and questions on socio-economic parameters)

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The procedure of enrolling patients for the prospective cohort of SwissPR patients is based on the participation in the CR program of the University Hospital Basel. Patients are routinely referred by various institutions for participation in the CR program according to predefined cardiovascular diagnosis.

You may qualify if:

• Participation in an ambulatory CR program (all age groups)
• Written informed consent

You may not qualify if:

• Inability to follow an ambulatory CR program more than 3 weeks
• Not willing to give informed consent
• Inability to understand the informed consent due to language comprehension
• Lack of discernment

Sponsors & Collaborators

• University Hospital, Basel, Switzerland: lead

Study Sites (1)

University Hospital Basel, Division of Outpatient Cardiology

Basel, 4031, Switzerland

RECRUITING

MeSH Terms

Conditions

Cardiovascular Diseases; Coronary Artery Disease; Acute Coronary Syndrome

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Otmar Pfister, Prof. Dr. med.

  Outpatient Cardiology, University Hospital Basel

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Otmar Pfister, Prof. Dr. med.

CONTACT

+41 61 328 7482; otmar.pfister@usb.ch

Steffen Biniasch

CONTACT

steffen.biniasch@usb.ch

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 15 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 8, 2022
• First Posted: August 15, 2022
• Study Start: December 20, 2019
• Primary Completion (Estimated): December 1, 2035
• Study Completion (Estimated): December 1, 2035
• Last Updated: July 22, 2025

Record last verified: 2025-07

Locations

CH (1)