Functional MRI Evaluation in Pyeloureteral Junction Syndrome in Children
Functional MRI Usage for Pyelo-ureteral Junction Syndrome : Results of Nancy Children Hospital Cohort
1 other identifier
observational
270
1 country
1
Brief Summary
Pyelo-ureteral junction syndrome is the most common urological abnormality in children. Functional MRI has been evaluated several times and has shown good correlation with scintigraphy, but tends to overestimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessels is limited. The investigators aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function. The secondary objectives are the evaluation of MRI performances to detect polar vessels; the comparison of surgery times depending on MRI-only realization or MRI and scintigraphy realization.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Sep 2022
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 10, 2022
CompletedFirst Posted
Study publicly available on registry
August 12, 2022
CompletedStudy Start
First participant enrolled
September 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 15, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2022
CompletedJune 16, 2026
August 1, 2022
14 days
August 10, 2022
June 15, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
MRI and scintigraphy differential renal function correlation
Evaluation of differential renal function between MRI and scintigraphy in children between 0 and 1 year old ; Pearson correlation coefficient
from january 2007 to december 2021
Secondary Outcomes (3)
MRI and scintigraphy differential renal function correlation in operated patient
from january 2007 to december 2021
Time difference in patient operated for PUJS depending on MRI realisation ou MRI and scintigraphy realisation
from january 2007 to december 2021
performance of MRI in detecting polar vessel
from january 2007 to december 2021
Study Arms (1)
PUJS patients
Patients between 0 and 17 years old treated or followed for pyelo-ureteral junction syndrome.
Interventions
Anatomical MRI : T2 fiesta, SSFE, HASTE ; 3D T2 ; T1 FAT SAT ; LAVA Functional MRI : T1 FAT SAT with gadolinium
Eligibility Criteria
Children between 0 and 17 years old followed for pyelo-ureteral junction syndrome in the Children hospital of Nancy.
You may qualify if:
- children between 0 and 17 years old
- followed for pyelo-ureteral junction syndrome
You may not qualify if:
- none
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHRU Nancy
Vandœuvre-lès-Nancy, Lorraine, 54 511, France
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Charles Mazeaud
CHRU Nancy
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Praticien hospitalier universitaire
Study Record Dates
First Submitted
August 10, 2022
First Posted
August 12, 2022
Study Start
September 1, 2022
Primary Completion
September 15, 2022
Study Completion
December 30, 2022
Last Updated
June 16, 2026
Record last verified: 2022-08