Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit

NCT05493982 | Enrolling By Invitation

• 2 other identifiers: 619651R01CA263121
• Study Type: interventional
• Target: 10,800
• Locations: 1 country
• Sites: 1

Brief Summary

The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students. A set of lessons focused on e-cigarette/vaping prevention education specifically is called the Be Vape Free curriculum. The aims of this study are to determine: (1) whether the Be Vape Free curriculum is effective in increasing middle and high school students' resistance to using tobacco and in decreasing positive attitudes towards and intentions to use e-cigarettes; (2) whether the Curriculum is effective in changing middle and high school students' actual use of tobacco; and (3) Examine heterogenous treatment effects identifying groups that benefit the most and those who do not benefit at all from the intervention.

Conditions

E-cigarette Use

Keywords

youth; tobacco; education; health; prevention; vaping; e-cigarette

Outcome Measures

Primary Outcomes (2)

• Change in e-cigarette use

  Investigator-originated survey measures (questions) assess ever e-cigarette use \& past 30-day tobacco use. This outcome measure assesses e-cigarette use.

  Change from baseline to follow-up at approximately 156 weeks

• Change in intention to use of e-cigarettes scaled score as measured by investigator-originated survey

  This survey measures change in intention to use e-cigarettes with questions related to the participant's knowledge of and resistance to use of e-cigarettes.

  Change from baseline to follow-up at approximately 156 weeks

Study Arms (3)

Receives Stanford vaping prevention curriculum (pilot phase)

EXPERIMENTAL

Stanford vaping prevention curriculum is administered as pilot arm preceding main experimental intervention.

Behavioral: Stanford Vaping Prevention curriculum

Receives Stanford vaping prevention curriculum (randomized phase)

EXPERIMENTAL

Stanford vaping prevention curriculum is administered.

Behavioral: Stanford Vaping Prevention curriculum

Does not receive Stanford vaping prevention curriculum (randomized phase)

NO INTERVENTION

Receives another curriculum or no vaping prevention education.

Interventions

Stanford Vaping Prevention curriculum BEHAVIORAL

Stanford vaping prevention curriculum delivered as a 5-session course administered in a school classroom setting.

Receives Stanford vaping prevention curriculum (pilot phase); Receives Stanford vaping prevention curriculum (randomized phase)

Eligibility Criteria

• Age: 10 Years - 20 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Middle school and high school students receiving health education at schools participating in the study

You may not qualify if:

• None

Sponsors & Collaborators

• Stanford University: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

Stanford University

Palo Alto, California, 94304, United States

Location

MeSH Terms

Conditions

Vaping

Condition Hierarchy (Ancestors)

Smoking; Behavior

Study Officials

• Bonnie Halpern-Felsher, Ph.D.

  Stanford University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Marron and Mary Elizabeth Kendrick Professor in Pediatrics II

Study Record Dates

• First Submitted: August 6, 2022
• First Posted: August 9, 2022
• Study Start: October 19, 2022
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026
• Last Updated: December 19, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)