Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis
POSIBIL6ESKD
A Phase 2b / 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Combined Dose-Finding and Cardiovascular Outcome Study to Investigate the Efficacy and Safety of CSL300 (Clazakizumab) in Subjects With End Stage Kidney Disease Undergoing Dialysis
2 other identifiers
interventional
2,310
32 countries
524
Brief Summary
This is a 2-part (phase 2b/3) prospective, interventional, multicenter, randomized, double-blind, placebo-controlled study. Part 1 (phase 2b) is a dose-finding study for CSL300 vs placebo. Part 2 (phase 3) aims to assess the efficacy of CSL300 on cardiovascular (CV) outcomes and safety in subjects with systemic inflammation and either atherosclerotic cardiovascular disease (ASCVD) or diabetes with end stage kidney disease (ESKD) undergoing maintenance dialysis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_2
Started Oct 2022
Longer than P75 for phase_2
524 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 29, 2022
CompletedFirst Posted
Study publicly available on registry
August 3, 2022
CompletedStudy Start
First participant enrolled
October 21, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 22, 2029
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 22, 2029
May 1, 2026
April 1, 2026
6.6 years
July 29, 2022
April 30, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Change from Baseline on the log scale in high-sensitivity C-reactive protein (hs-CRP)(Phase 2b)
Baseline and up to 12 weeks
Time to first occurrence of CV death or myocardial infarction (MI) (Phase 3)
Approximately 5 years
Secondary Outcomes (38)
Percent of participants achieving hs-CRP less than (<) 2.0 milligram per Liter (mg/L) (Phase 2b)
Week 12
Change from baseline in log-transformed hs-CRP (Phase 2b)
Baseline and up to 24 weeks
Mean change from Baseline in serum amyloid A (SAA) (Phase 2b)
Baseline and up to 12 weeks
Mean change from Baseline in secretory phospholipase A2 (sPLA2) (Phase 2b)
Baseline and up to 12 weeks
Mean change from Baseline in fibrinogen (Phase 2b)
Baseline and up to 12 weeks
- +33 more secondary outcomes
Study Arms (6)
CSL300 (low dose)(Phase 2b)
EXPERIMENTALIntravenous (IV) administration
CSL300 (medium dose)(Phase 2b)
EXPERIMENTALIV administration
CSL300 (high dose)(Phase 2b)
EXPERIMENTALIV administration
Placebo (Phase 2b)
PLACEBO COMPARATORIV administration
CSL300 (Phase 3)
EXPERIMENTALIV administration
Placebo (Phase 3)
PLACEBO COMPARATORIV administration
Interventions
IV administration
Matching the excipient content and concentration of the CSL300 product, minus the active ingredient.
Eligibility Criteria
You may qualify if:
- \- Male or female at least 18 years of age
- \- A diagnosis of ESKD undergoing maintenance dialysis for at least 12 weeks
- \- Serum hs-CRP ≥ 2.0 mg/L
- \- A diagnosis of diabetes mellitus OR ASCVD
You may not qualify if:
- \- Subjects who participated in Part 1 (phase 2b) are not eligible to participate in Part 2 (phase 3)
- \- Concomitant use of systemic immunosuppressant drugs
- \- Abnormal LFTs
- \- Any life-threatening disease expected to result in death within 12 months
- \- A history of GI perforation, inflammatory bowel disease (except fully excised ulcerative colitis), or peptic ulcer disease
- Clinically significant active infection or history of opportunistic or invasive fungal infection
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- CSL Behringlead
Study Sites (542)
Nephrology of North Alabama
Decatur, Alabama, 35601, United States
Nephrology Consultants, LLC
Huntsville, Alabama, 35805, United States
DaVita Clinical Research Montgomery
Montgomery, Alabama, 36117, United States
AKDHC Medical
Glendale, Arizona, 85305, United States
Kidney Disease Medical Group
Glendale, Arizona, 91206, United States
AKDHC Medical
Phoenix, Arizona, 85018, United States
AKDHC Medical
Tucson, Arizona, 85705, United States
Southern Arizona VA Health Care System
Tucson, Arizona, 85723, United States
National Institute of Clinical Research
Bakersfield, California, 93309, United States
Amicis Research Center
Beverly Hills, California, 90211, United States
California Institute of Renal Research
Chula Vista, California, 91910, United States
The Medical Research Group, Inc.
Fresno, California, 93720, United States
Davita Fullerton Dialysis Center
Fullerton, California, 92832, United States
National Institute of Clinical Research, Inc.
Fullerton, California, 92835, United States
National Institute of Clinical Research, Inc.
Garden Grove, California, 92843, United States
St. Jude Medical Center
Garden Grove, California, 92843, United States
National Institute of Clinical Research
Garden Grove, California, 92844, United States
Sherman Medical Group, Inc
Glendale, California, 91204, United States
Kidney Disease Medical Group
Glendale, California, 91206, United States
Renal Consultants Medical Group
Granada Hills, California, 91344, United States
Balboa Research
La Jolla, California, 92037, United States
California Institute of Renal Research
La Mesa, California, 91942, United States
Southern California Medical Research Center
La Palma, California, 90623, United States
Academic Medical Research Institute
Los Angeles, California, 90022, United States
National Institute of Clinical Research, Inc.
Los Angeles, California, 90027, United States
DaVita Carabello Dialysis Center
Los Angeles, California, 90033, United States
Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
Renal Medical Associates/NARI
Lynwood, California, 90262, United States
Amicis Research Center
Northridge, California, 91324, United States
FORMAT Medical Research
Oxnard, California, 93036, United States
Van Buren Dialysis Center
Riverside, California, 92504, United States
National Nephrology Alliance Research - Riverside
Riverside, California, 92505, United States
Central Coast Nephrology Medical Corp
Salinas, California, 93901, United States
California Institute of Renal Research
San Diego, California, 92111, United States
California Institute of Renal Research
San Diego, California, 92123, United States
North America Research Institute
San Dimas, California, 91773, United States
Satellite Healthcare
San Jose, California, 95126, United States
Nephrology Educational Services
Tarzana, California, 91356, United States
Valiance Clinical Research
Tarzana, California, 91356, United States
Amicis Research Center
Vacaville, California, 95687, United States
National Institute of Clinical Research, Inc
Victorville, California, 92392, United States
DaVita Vista Del Sol Dialysis
Victorville, California, 92394, United States
Western Nephrology
Arvada, Colorado, 80002, United States
Kidney Associates of Colorado, P.C.
Denver, Colorado, 80210, United States
Colorado Kidney Care
Denver, Colorado, 80230, United States
Greater Hartford Nephrology, LLC
Bloomfield, Connecticut, 06002, United States
Nephrology and Hypertension Associates PC
Middlebury, Connecticut, 06762, United States
Nephrology Associates (Delaware)
Newark, Delaware, 19713, United States
- Boca Raton Regional - Research Physicians Network Alliance
Boca Raton, Florida, 33431, United States
Nova Clinical Research, LLC
Bradenton, Florida, 34209, United States
Access Research Institute
Brooksville, Florida, 34613, United States
Horizon Research Group LLC
Coral Gables, Florida, 33134, United States
South Florida Nephrology Group, PA
Coral Springs, Florida, 33071, United States
Family First Medical Research Center
Hialeah Gardens, Florida, 33016, United States
Advanced Medical Research Group
Hollywood, Florida, 33021, United States
Royal Research, Corp
Hollywood, Florida, 33021, United States
Elixia Pines
Hollywood, Florida, 33024, United States
South Florida Research Institute
Lauderdale Lakes, Florida, 33313, United States
South Florida Research Organization LLC
Medley, Florida, 33166, United States
Aviva Health Sciences
Miami, Florida, 33125, United States
Iconic Clinical Research Center
Miami, Florida, 33126, United States
Total Research Group, LLC
Miami, Florida, 33126, United States
Kidney and Hypertension Specialists of Miami
Miami, Florida, 33150, United States
Nephrology Associates of South Miami
Miami, Florida, 33173, United States
Floridian Clinical Research
Miami Lakes, Florida, 33016, United States
Elixia Central Florida
Orlando, Florida, 32806, United States
Infigo Clinical Research LLC
Sanford, Florida, 32771, United States
Genesis Clinical Research
Tampa, Florida, 33603, United States
Florida Kidney Specialists
Temple Terrace, Florida, 33637, United States
Florida Premier Research Institute
Winter Park, Florida, 32789, United States
Southwest Georgia Nephrology Clinic
Albany, Georgia, 31701, United States
Coastal Medical Research, LLC
Brunswick, Georgia, 31520, United States
Renal Associates LLC
Columbus, Georgia, 31904, United States
National Clinical Trials
Cordele, Georgia, 31015, United States
American Clinical Trials
Douglasville, Georgia, 30101, United States
Georgia Nephrology
Lawrenceville, Georgia, 30046, United States
Atekha Nephrology Clinic LLC
Statesboro, Georgia, 30458, United States
NANI Research
Fort Wayne, Indiana, 46804, United States
Nephrology Physician's LLC
Mishawaka, Indiana, 46545, United States
Dunes Clinical Research LLC
Sioux City, Iowa, 57049, United States
Kansas Nephrology Physicians, PA
Wichita, Kansas, 67214, United States
Nephrology Associates of Kentuckiana, PSC
Louisville, Kentucky, 40205, United States
Renal Associates of Baton Rouge
Baton Rouge, Louisiana, 70808, United States
Tufts Medical Center
Boston, Massachusetts, 02111, United States
Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
Paragon Health, Inc
Kalamazoo, Michigan, 49007, United States
Michigan Kidney Consultants, PC
Pontiac, Michigan, 48341, United States
St. Clair Nephrology Research
Roseville, Michigan, 48066, United States
Center for Advanced Kidney Research, PLC
Saint Clair Shores, Michigan, 48081, United States
DCR Edina
Minneapolis, Minnesota, 55404, United States
DCR Edina
Minneapolis, Minnesota, 55404, United States
Minneapolis VA Health Care System
Minneapolis, Minnesota, 55439, United States
Southwest Mississippi Nephrology PLLC
Brookhaven, Mississippi, 39601, United States
Nephrology Associates, PC
Columbus, Mississippi, 39705, United States
- Nephrology and Hypertension Associates Ltd
Tupelo, Mississippi, 38801, United States
Clinical Research Consultants
Kansas City, Missouri, 64111, United States
Kansas City VA Medical Center
Kansas City, Missouri, 64128, United States
DCI-Rockhill
Kansas City, Missouri, 64131, United States
GSR Enterprises, Inc.
Lincoln, Nebraska, 68510, United States
Great Plains Health - Nephrology
North Platte, Nebraska, 69101, United States
DaVita Clinical Research - Henderson
Henderson, Nevada, 89074, United States
Kidney Specialists of Southern Nevada
Las Vegas, Nevada, 89106, United States
Sierra Nevada Specialty Care
Reno, Nevada, 89511, United States
Seacoast Kidney and Hypertension Specialists
Portsmouth, New Hampshire, 03801, United States
Hypertension & Nephrology Association
Eatontown, New Jersey, 07724, United States
New Jersey Kidney Care
Jersey City, New Jersey, 07305, United States
U.S. Renal Care - Gallup
Gallup, New Mexico, 87301, United States
Albany Medical College Committee of Research Involving Human Subjects
Albany, New York, 12208, United States
SUNY Downstate Medical Center Brooklyn
Brooklyn, New York, 11203, United States
Mattoo & Bhat Medical Associates, P.C.
College Point, New York, 11356, United States
NYU Langone Hospital - Long Island
Mineola, New York, 11501, United States
DaVita Clinic Research Bronx
The Bronx, New York, 10461, United States
Albert Einstein College of Medicine - Montefiore Medical Center
The Bronx, New York, 10467, United States
James J Peters VA Medical Center
The Bronx, New York, 10468, United States
Metrolina Nephrology Associates, PA
Charlotte, North Carolina, 28204, United States
Durham Nephrology Associates, PA
Durham, North Carolina, 27704, United States
Duke Translational Medicine Institute
Durham, North Carolina, 27705, United States
East Carolina University
Greenville, North Carolina, 27858, United States
Eastern Nephrology Associates, PLLC
Kinston, North Carolina, 28504, United States
North Carolina Nephrology, PA
Raleigh, North Carolina, 27610, United States
Nephrology Associates of the Carolinas
Shelby, North Carolina, 28150, United States
HNC Dialysis, Ltd.
Columbus, Ohio, 43215, United States
Northeast Clinical Research Center, LLC
Bethlehem, Pennsylvania, 18017, United States
Clinical Renal Associates, LTD
Exton, Pennsylvania, 19341, United States
Lifespan Clinical Research
East Providence, Rhode Island, 02915, United States
Columbia Nephrology
Columbia, South Carolina, 29203, United States
Dialysis Clinic, Inc.
Spartanburg, South Carolina, 29301, United States
DaVita Clinical Research
Spartanburg, South Carolina, 29306, United States
Southeast Renal Research Institute
Chattanooga, Tennessee, 37404, United States
Dialysis Clinic Inc - University Nephology
Knoxville, Tennessee, 37920, United States
Knoxville Kidney Center PLLC
Knoxville, Tennessee, 37923, United States
Lt. Col. Luke Weathers, Jr. VA Medical Center
Memphis, Tennessee, 38105, United States
Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
Cussimanio Research Group LLC
Austin, Texas, 78751, United States
Research Management, Inc.
Austin, Texas, 78758, United States
MW Clinical Research Center
Beaumont, Texas, 77701, United States
Dallas V.A. Medical Center
Dallas, Texas, 75216, United States
Dallas Nephrology Associates
Dallas, Texas, 75234, United States
US Renal Care
Dallas, Texas, 75237, United States
Davita Clinical Research
El Paso, Texas, 79925, United States
DaVita Clinical Research - Horizon
El Paso, Texas, 79935, United States
Fort Worth Renal Group
Fort Worth, Texas, 76110, United States
Clinical Research Strategies
Houston, Texas, 77030, United States
DaVita Clinical Research
Houston, Texas, 77054, United States
Aqua Research Institute
Houston, Texas, 77058, United States
Gulf Coast Clinical Research
Houston, Texas, 77070, United States
Houston Medical Research Institute, LLC
Houston, Texas, 77074, United States
Clinical Research Strategies, Inc.
Houston, Texas, 77090, United States
Southwest Houston Research
Houston, Texas, 77099, United States
Laguna Clinical Research Associates, LLC
Laredo, Texas, 78041, United States
Prime Clinical Research, Inc.
Mansfield, Texas, 76063, United States
Gamma Medical Research, Inc.
McAllen, Texas, 78503, United States
National Institute of Clinical Research, Inc.
San Antonio, Texas, 78204, United States
DaVita Clinical Research
San Antonio, Texas, 78229, United States
Davita Clinical Research
San Antonio, Texas, 78251, United States
DCR-San Antonio Stone Oak
San Antonio, Texas, 78258, United States
DaVita Clinical Research North Houston
Shenandoah, Texas, 77384, United States
Medrasa Clinical Research
Sherman, Texas, 75092, United States
Renal Research of Montgomery County
The Woodlands, Texas, 77384, United States
DCR-Norfolk Great Bridge
Chesapeake, Virginia, 23320, United States
Nephrology Associates of Northern Virginia Inc
Fairfax, Virginia, 22033, United States
Peninsula Kidney Associates
Hampton, Virginia, 23666, United States
Tidewater Kidney Specialists
Norfolk, Virginia, 23502, United States
Nephrology and Hypertension Associates
Bluefield, West Virginia, 24701, United States
FME Lomas de Zamora
Banfield, 1828, Argentina
FME Mansilla
Buenos Aires, 1425, Argentina
Instituto de Trasplante De La Ciudad Autonoma De Buenos Aires
Buenos Aires, 6022, Argentina
FME Avellaneda
Buenos Aires, B1870ARU, Argentina
FME Cemic Saavedra
Ciudad Autonoma, C1431FWO, Argentina
CEREHA
Ciudad de Buenos Aires, C1426, Argentina
Fresenius Medical Care - Ciudad Evita
Ciudad Evita, B1778IFA, Argentina
Clinica Privada Velez Sarsfield
Córdoba, 5016, Argentina
FME Formosa
Formosa, 3600, Argentina
STR Hurlingham SRL
Hurlingham, B 1686, Argentina
Nextdial S.A.
Mar del Plata, 7600, Argentina
Fresenius Medical Care - Nostri Centri Dialisi - Moron
Morón, B1708DPO, Argentina
Instituto Medico de la Fundacion de Estudios Clínicos
Rosario, S2000DEJ, Argentina
Fresenius Tucumán
San Miguel de Tucumán, 4000, Argentina
Royal North Shore Hospital (RNSH)
Saint Leonards, New South Wales, 2065, Australia
Concord Repatriation General Hospital
Sydney, New South Wales, 2139, Australia
Cairns Hospital
Cairns, Queensland, 4870, Australia
Sunshine Coast University Private Hospital
Nambour, Queensland, 4560, Australia
Princess Alexandra Hospital
Woolloongabba, Queensland, 4102, Australia
Monash Medical Centre
Clayton, Victoria, 3168, Australia
Sunshine Hospital
St Albans, Victoria, 3021, Australia
Wide Bay Hospital and Health Service
Bundaberg, 4670, Australia
Austin Hospital
Heidelberg, 3084, Australia
Liverpool Hospital
Liverpool, 2170, Australia
Fiona Stanley Hospital
Murdoch, 6150, Australia
Sunshine Coast University Private Hospital
Nambour, 4560, Australia
Royal Melbourne Hospital
Parkville, 3052, Australia
Gold Coast University Hospital
Southport, 4215, Australia
Fraser Coast Renal Service, Hervey Bay Hospital
Urraween, 4655, Australia
Sydney Adventist Hospital
Wahroonga, 2076, Australia
Westmead Hospital
Westmead, 2145, Australia
Wollongong Renal Unit
Wollongong, 2500, Australia
Wiener Gesundheitsverbund - Klinik Hietzing
Vienna, 1130, Austria
Onze-Lieve-Vrouwziekenhuis VZW
Aalst, 9300, Belgium
Imelda Ziekenhuis
Bonheiden, 2820, Belgium
Centre Hospitalier Universitaire (CHU) de Charleroi - Hopital Civil Marie Curie
Charleroi, 6042, Belgium
AZ Sint-Lucas
Ghent, 9000, Belgium
Centre Hospitalier Universitaire de Tivoli
La Louvière, 7100, Belgium
Jan Yperman Ziekenhuis
Leper, 8900, Belgium
Universitair Ziekenhuis Leuven
Leuven, 3000, Belgium
CHR de la Citadelle
Liège, 4000, Belgium
AZ Delta (H.-Hartziekenhuis Roeselare-Menen vzw (HHRM)) - Campus Rumbeke
Roeselare, 8800, Belgium
VITAZ, Department Nierziekten & Dialyse
Sint-Niklaas, 9100, Belgium
Santa Casa de Misericordia de Belo Horizonte
Belo Horizonte, 30150-320, Brazil
NUPEC-Nucleo de Pesquisa Clinica
Belo Horizonte, 30220-140, Brazil
Hospital Universitário Walter Cantídio (Fortaleza)
Fortaleza, 60430-372, Brazil
Fundacao Pro Rim de Santa Catarina
Joinville, 89227-680, Brazil
Clipem - Clínica o Pesquisa Endocrinológica de Maringá
Maringá, 87060-040, Brazil
Hospital de Clinicas de Passo Fundo
Passo Fundo, 9910-260, Brazil
Irmandade Santa Casa de Misericordia de Porto Alegre
Porto Alegre, 90035-074, Brazil
Hospital de Clinicas de Porto Alegre
Porto Alegre, 90035-903, Brazil
Hospital São Lucas da PUCRS
Porto Alegre, 90610-001, Brazil
CEDOES - Centro de Diagnostico e Pesquisa
Praia Do Canto, 29055-450, Brazil
Universidade de Sao Paulo (USP)-Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto (HCFMRP)
Ribeirão Preto, 14015-130, Brazil
SERVIÇO DE NEFROLOGIA DE RIBEIRÃO Preto (SENERP)
Ribeirão Preto, 14025-170, Brazil
Clinica Senhor do Bonfim Ltda (CSB) - Monte Serrat
Salvador, 40415-065, Brazil
Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto
São José do Rio Preto, 15090-000, Brazil
Hospital das Clínicas da Faculdade de Medicina da Universidade de Sao Paulo
São Paulo, 01246-903, Brazil
Hospital Alemao Oswaldo Cruz
São Paulo, 01323-020, Brazil
Hospital do Rim e Hipertensão
São Paulo, 04024-002, Brazil
Hospital Santa Marcelina
São Paulo, 08270-070, Brazil
Hospital 9 de Julho
São Paulo, 1409-902, Brazil
Multiprofile Hospital for Active Treatment - Dobrich AD
Dobrich, 9300, Bulgaria
Multiprofile Hospital For Active Treatment Dr Tota Venkova
Gabrovo, 5300, Bulgaria
Multiprofile Hospital for Active Treatment- Sveti Nikolay Chudotvoretz - LOM EOOD
Lom, 3600, Bulgaria
Dialysis Centre Montana
Montana, 3400, Bulgaria
University Multiprofile Hospital for Active Treatment Sveti Georgi EAD
Plovdiv, 4002, Bulgaria
UMHAT Plovdiv
Plovdiv, 4003, Bulgaria
Multiprofile Hospital for Active Treatment Dr. Ivan Seliminski - Sliven AD
Sliven, 6600, Bulgaria
Medical Center - Smolyan OOD
Smolyan, 4700, Bulgaria
UMHAT Aleksandrovska
Sofia, 1432, Bulgaria
University Hospital for Active Treatment Tsaritsa Joanna ISUL EAD
Sofia, 1527, Bulgaria
Dialysis Center VIA DIAL OOD
Stara Zagora, 6000, Bulgaria
UMHAT Prof. Dr. Stoyan Kirkovich
Stara Zagora, 6000, Bulgaria
University of Alberta Hospital
Edmonton, Alberta, T6G2P4, Canada
Queen Elizabeth II Health Sciences Centre
Halifax, Nova Scotia, B3H 3A6, Canada
St. Josephs Healthcare Hamilton
Hamilton, Ontario, L8N 4A6, Canada
Kingston Health Sciences Centre
Kingston, Ontario, K7L 2V7, Canada
London Health Sciences Centre - University Hospital
London, Ontario, N6A 5A5, Canada
Lakeridge Health Oshawa
Oshawa, Ontario, L1G 2B9, Canada
McGill University Health Centre
Montreal, Quebec, H4A 3J1, Canada
Hôpital du Sacré-Cœur-de-Montréal
Montreal, Quebec, H4J 1C5, Canada
Hospital Charles Lemoyne
Longueuil, J4V 2H1, Canada
Maisonneuve-Rosemont Hospital
Montreal, H1T 2M4, Canada
CHUM - Centre hospitalier de l'Universite de Montreal
Montreal, H2X 3E4, Canada
The Ottawa Hospital Research Institute
Ottawa, K1H 8L6, Canada
Ciussse-Chus
Sherbrooke, J1H 5N4, Canada
St. Michaels Hospital
Toronto, M5B 1W8, Canada
St Paul Hospital
Vancouver, V6Z 1Y6, Canada
Seven Oaks Hospital
Winnipeg, R2V 3M3, Canada
Inner Mongolia Baotou City Central Hospital (Baotou Central Hospital)
Baotou Shi, 14040, China
Peking University People's Hospital
Beijeing, 100033, China
Peking University First Hospital
Beijing, 100034, China
China Rehabilitation Research Center (Beijing Boai Hospital)
Beijing, 100068, China
Peking University Third Hospital
Beijing, 100191, China
Beijing Miyun Hospital
Beijing, 101500, China
Beijing Tsinghua Chang Gung Hospital
Beijing, 102218, China
The Affiliated Zhongshan Hospital (Dalian Railroad Hospital)
Dalian, 116001, China
People's Hospital of Deyang
Deyang Shi, 618000, China
Dongguan People's Hospital
Dongguan, 523059, China
The Fifth Affiliated Hospital of Guangzhou Medical University
Guangzhou, 510700, China
Anhui Medical University-The Second Hospital
Hefei, 230601, China
The First Hospital of Jiaxing
Jiaxing, 314001, China
Jiangsu Province Hospital /The First Affiliated Hospital with Nanjing Medical University
Lanzhou, 210029, China
Gansu Provincial People's Hospital
Lanzhou, 730000, China
Henan University of Science and Technology-The First Affiliated Hospital
Luoyang Shi, 471003, China
The Third Hospital of Mianyang
Mianyang, 621000, China
Nanchang University - The First Affiliated Hospital
Nanchang, 330006, China
The Second Affiliated Hospital of Nanjing Medical University
Nanjing, 210003, China
Jiangsu Province Hospital of Chinese Medicine
Nanjing, 210029, China
The People's Hospital Guangxi Zhuang of Autonomous Region
Nanning, 530021, China
Southern Medical University - Jiangxi Pingxiang People's Hospital
Pingxiang, 337055, China
Shanghai Jiao Tong University School of Medicine (SJTUSM)-Renji Hospital
Shanghai, 200001, China
Shanghai First People's Hospital
Shanghai Shi, 200080, China
Shenzhen Second People's Hospital (Shenzhen University First Affiliated Hospital)
Shenzhen, 518035, China
Shijiazhuang People's Hospital
Shijiazhuang, 050011, China
The Fourth Hospital of Hebei Medical University
Shijiazhuang, 50011, China
Second Hospital of Shanxi Medical University
Taiyuan, 030001, China
Tianjin People's Hospital
Tianjin, 300071, China
Huazhong University of Science and Technology - Tongji Medical College - The Central Hospital of Wuhan (Wuhan Second Hospital)
Wuhan, 430014, China
Renmin Hospital of Wuhan University/Hubei General Hospital
Wuhan, 430060, China
Wuxi People's Hospital
Wuxi, 214023, China
Zhongshan Hospital Xiamen University
Xiamen, 361004, China
Yan'an University Xianyang Hospital
Xianyang, 712099, China
Xinxiang City First People's Hospital
Xinxiang, 453000, China
Northern Jiangsu People's Hospital
Yangzhou, 225001, China
Yibin Second People's Hospital
Yibin, 644000, China
The First Affiliated Hospital of Zhengzhou University
Zhengzhou, 450052, China
Affiliated Hospital of Jiangsu University
Zhenjiang, 212001, China
Interni Oddeleni Nemocnice
Český Krumlov, 381 01, Czechia
Fakultni Nemocnice Hradec Kralove (FNHK) - Hemodialyzacni Stredisko (HDS)
Hradec Králové, 500 05, Czechia
Nemocnice AGEL Novy Jicin a.s
Nový Jičín, 741 01, Czechia
Fakultní Nemocnice Ostrava (FNO) - Interni Klinika
Ostrava, 708 00, Czechia
Fakultní nemocnice Královské Vinohrady
Prague, 100 34, Czechia
Aalborg Universitetshospital
Aalborg, 9000, Denmark
Herlev Hospital
Herlev, 2730, Denmark
Gødstrup Hospital
Herning, 7400, Denmark
Trail Nation: Nordsjællands Hospital
Hillerød, 3400, Denmark
Trial Nation: Holbæk Sygehus
Holbæk, 4300, Denmark
CHU Amiens - Nephrology Dialysi Transplantation Department
Amiens, 80054, France
CHU de Saint-Étienne - Hôpital Nord
Aura, 42055, France
Centre Hospitalier Regional Universitaire (CHRU) Brest - Hopital de la Cavale Blanche
Brest, 29200, France
CHU de Caen
Caen, 14000, France
Polyclinique Saint Come - Centre de Dialyse
Compiègne, 60200, France
Fondation Charles Mion AIDER Santé
Grabels, 34790, France
Hopital Prive La Louviere
Lille, 59000, France
CHU de Limoges
Limoges, 87042, France
Hopitaux Universitaires de Marseille
Marseille, 13005, France
Centre Hospitalier Universitaire Montpellier - Hôpital Lapeyronie
Montpellier, 34295, France
CHE de Nice - Pasteur Hospital
Nice, 6000, France
CHU de Nimes - Hopital Universitaire Caremeau
Nîmes, 30029, France
Hopital Pitie-Salpetriere
Paris, 75013, France
AURA Paris - Plaisance
Paris, 75014, France
Centre Hospitalier Universitaire (CHU) de Reims - Hopital Maison Blanche
Reims, 51092, France
AURA St Quen Dialysis centre
Saint-Ouen, 93400, France
Hôpitaux Universitaires de Strasbourg - Hôpital Civil
Strasbourg, 67091, France
CHU Rangueil
Toulouse, 31059, France
Charite-Universitatsmedizin Berlin
Berlin, 13353, Germany
Nierenzentrum Bad König
Hessen, 64732, Germany
Westpfalz Klinikum GmbH
Kaiserslautern, 67655, Germany
UKSH - Universitatsklinik Schleswig-Holstein
Kiel, 24105, Germany
Kuratorium fuer Dialyse und Nierentransplantation e.V. - KfH-Nierenzentrum - St. Georg
Leipzig, 04129, Germany
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Mainz, 55131, Germany
Nephrologisches Zentrum Villingen-Schwenningen
Villingen-Schwenningen, 78052, Germany
University Hospital of Alexandroupolis
Alexandroupoli, 68100, Greece
General Hospital of Arta
Arta, 471 00, Greece
University General Hospital of Heraklion
Crete, 71500, Greece
Mesogeios Nephrology Center
Haidari, 12461, Greece
University General Hospital of Ioannina
Ioannina, 45110, Greece
General Hospital of Ioannina G. Hatzikosta
Ioannina, 45445, Greece
Nephrological Clinic University Hospital, University of Thessaly
Larissa, 41110, Greece
Mitera Hospital, Hemodialysis Unit
Marousi, 15123, Greece
General Hospital of Ptolemaida
Ptolemaida, 50200, Greece
University Hospital of Patras
Rio, 265 04, Greece
AHEPA Univ. Hospital, Medical School, Aristotle University of Thessaloniki
Thessaloniki, 45500, Greece
Aristotle University, Hippokration
Thessaloniki, 54642, Greece
General Hospital of Thessaloniki, Agios Pavlos
Thessaloniki, 55134, Greece
Papageorgiou General Hospital of Thessaloniki
Thessaloniki, 56403, Greece
Nephrology Department G. Papanikolaou General Hospital
Thessaloniki, 570 10, Greece
Princess Margaret Hospital
Ho Man Tin, 999077, Hong Kong
Queen Mary Hospital Hong Kong
Pok Fu Lam, 852, Hong Kong
Yan Chai Hospital
Tsuen Wan, 999077, Hong Kong
Somogy Megyei Kaposi Mor Oktato Korhaz
Kaposvár, 7400, Hungary
B. Braun Avitum - 14. Dialízisközpont Kistarcs
Kistarcsa, 2143, Hungary
Emek Medical Center
Afula, 18105, Israel
Barzilai Medical Center
Ashkelon, 7830604, Israel
Carmel Medical Center
Haifa, 3436212, Israel
Edith Wolfson Medical Center
Holon, 58100, Israel
Galilee Medical Center
Nahariya, 2244624, Israel
Rabin Medical Center
Petah Tikva, 4941492, Israel
Chaim Sheba Medical Center (Sheba Tel-Hashomer Medical Center )
Ramat Gan, 3109601, Israel
Kaplan Medical Center
Rehovot, 7661041, Israel
Ziv Medical Center
Safed, 13110, Israel
Ichilov Hospital-Tel-Aviv Sourasky Medical Center
Tel Aviv, 84100, Israel
Medical Research & Development Fund for Health Services, PORIYA Hospital
Tiberias, 15208, Israel
Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi
Bologna, 40138, Italy
ASST degli Spedali Civili di Brescia
Brescia, 25123, Italy
Azienda Ospedaliera Brotzu
Cagliari, 9100, Italy
Azienda Ospedaliera Sant'Anna e San Sebastiano di Caserta
Caserta, 81100, Italy
AOU Policlinico G Rodolico - San Marco - Presidio Ospedaliero ospedale San Marco
Catania, 95121, Italy
Azienda Ospedaliero-Universitaria di Ferrara - Arcispedale Sant'Anna
Ferrara, 44124, Italy
Ospedale Santa Maria Annunziata
Florence, 50012, Italy
A. O. -Universitaria Ospedali Riuniti di Foggia Farmacia Osp
Foggia, 71122, Italy
IRCCS Az. Osp. Universitaria San Martino- IST
Genova, 16132, Italy
Vito Fazzi Hospital in Lecce
Lecce, 73100, Italy
ASST di Lecco - Presidio Ospedaliero A. Manzoni di Lecco
Lecco, 23900, Italy
Università degli Studi di Messina
Messina, 98124, Italy
ASST Santi Paolo e Carlo - Ospedale San Carlo Borromeo
Milan, 20142, Italy
IRCCS Ospedale San Raffaele
Milan, 20132, Italy
ASST Great Metropolitan Hospital Niguarda
Milan, 20162, Italy
AOU L. Vanvitelli Universita degli Studi della Campania Luigi Vanvitelli
Naples, 80138, Italy
Ospedale Maggiore di Novara
Novara, 28100, Italy
ICS Maugeri S.p.A. SB; Università di Pavia; Fondazione Salvatore Maugeri IRCCS
Pavia, 2700, Italy
University of Verona
Peschiera del Garda, 37019, Italy
AUSL Piacenza Hospital-Unit Nephrology Dialysis, Dept of Medicine
Piacenza, 29121, Italy
Azienda Ospedaliero Universitaria Pisana - Ospedale di Cisanello - Stabilimento Ospedaliero di Cisanello
Pisana, 56124, Italy
Ospedale Santo Stefan
Prato, 59100, Italy
Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli
Reggio Calabria, 89124, Italy
Rimini Hospital
Rimini, 47923, Italy
Policlinico A. Gemelli Universitario
Roma, 168, Italy
Azienda Unita Sanitaria Locale (USL) Roma 3 (AUSL RM 3) - Presidio Ospedaliero Giovan Battista Grassi
Rome, 00122, Italy
Sandro Pertini Hospital
Rome, 1577, Italy
Ospedale Casa Sollievo della Sofferenza (CSS)
San Giovanni Rotondo, 71013, Italy
Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Trento
Verona, 37126, Italy
Daiyukai Daiichi Hospital
Ichinomiya-shi, Aichi-ken, 491-8551, Japan
Juntendo University Urayasu Hospital
Urayasu-shi, Chiba, 279-0021, Japan
Steel Memorial Yawata Hospital
Kitakyushu-shi, Fukuoka, 805-0050, Japan
Maebashi Hirosegawa Clinic
Maebashi, Gunma, 371-0022, Japan
Joumou Ohashi Clinic
Maebashi, Gunma, 371-0046, Japan
Teine Urological Clinic
Sapporo, Hokkaido, 006-0816, Japan
Omi freai Hospital
Kusatsu-shi, Shiga, 525-8585, Japan
Tokyo Womens Med University
Shinjuku-Ku, Tokyo, 162-8666, Japan
Matsunami General Hospital
Hashima-gun, 501-6062, Japan
Ishikiriseiki Hospital
Higashiosaka-shi, 579-8026, Japan
NHO Hiroshimanishi Medical Center
Hiroshima, 739-0696, Japan
Miki Internal Medicine Urology Clinic
Hokkaido, 041-1121, Japan
Tokyo Medical University Ibaraki Medical Center
Inashiki-gun, 300-0332, Japan
Ueyama Hospital
Kagoshima, 890-0073, Japan
Ueyama Jin Clinic
Kagoshima, 890-0073, Japan
Shonan Kamakura General Hospital
Kamakura-Shi, 247-8533, Japan
National Hospital Organization Kanazawa Medical Center
Kanazawa, 920-8650, Japan
Kokura Memorial Hospital
Kitakyushu-Shi, 802-8555, Japan
Kurume University Hospital
Kurume, 830-0011, Japan
St. Mary's Hospital
Kurume-shi, 830-8543, Japan
Rakuwakai Otowa Kinen Hospital
Kyoto, 607-8116, Japan
Matsubara Tokushukai Hospital
Matsubara-shi, 580-0032, Japan
Nagaoka Red-Cross Hospital
Nagaoka-Shi, 940-2085, Japan
Chubu Rosai Hospital
Nagoya, 455-8530, Japan
Daido Hospital
Nagoya, 457-8511, Japan
Ogaki Tokushukai Hospital
Ogaki-Shi, 503-0015, Japan
Oguranaika Jin Cinic
Oyama-shi, 323-0831, Japan
Omihachiman Community Medical Center - Kidney Center
Ōmihachiman, 523-0082, Japan
Ibaraki Seinan Medical Center Hospital
Sakaimachi, 306-0433, Japan
Kurosawa Hospital
Takasaki-Shi, 370-1203, Japan
Kikuchi Medical Clinic
Tsukuba, 305-0861, Japan
St.Hill Hospital
Ube-shi, 755-0155, Japan
Yamagata Tokushukai Hospital
Yamagata, 990-0834, Japan
Bosei Kannai Clinic
Yokohama, 231-0048, Japan
Sanin Rosai Hospital
Yonago-shi, 683-8605, Japan
Hospital Raja Permaisuri Bainun, Ipoh
Ipoh, 31400, Malaysia
Queen Elizabeth Hospital
Kota Kinabalu, 88300, Malaysia
University Malaya Medical Centre
Lembah Pantai, 59100, Malaysia
Hospital Kuala Lumpur
Pejabat Pakar, 50586, Malaysia
Seberang Jaya Hospital
Perai, 13700, Malaysia
Seri Manjung Hospital
Perak, 32040, Malaysia
Vestre Viken HF - Drammen Sykehus (Sykehuset Buskerud)
Drammen, 3004, Norway
Sykehuset Østfold Kalnes
Grålum, 1714, Norway
Sykehuset Telemark
Skien, 3710, Norway
Davita Stacja Dializ w Brodnicy
Brodnica, 87-300, Poland
Slaski Uniwersytet Medyczny (SUM) w Katowicach
Katowice, 40-027, Poland
Uniwersytecki Szpital Kliniczny Nr. 1 im. Norberta Barlickiego
Lodz, 90-153, Poland
Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodz, Klinika Nefrologii, Hipertensjologii i Transplantologii Nerek
Lodz, 92-213, Poland
DaVita Stacja Dializ
Pszczyna, 43-200, Poland
Powiatowy Szpital Specjalistyczny w Stalowej Woli
Stalowa Wola, 37-450, Poland
Samodzielny Publiczny Szpital Kliniczny Nr. 2 Pomorski Uniwersytet Medyczny w Szczecinie
Szczecin, 70-111, Poland
Diaverum - NZOZ Tczewie
Tczew, 83-110, Poland
DaVita Stacja Dializ
Warsaw, 01-211, Poland
Wojskowy Instytut Medyczny (WIM) - Centralny Szpital Kliniczny (CSK) MON - Klinika Chorob Wewnetrznych
Warsaw, 04-349, Poland
Davita-Łęczna
Łęczna, 21-010, Poland
Unidade Local de Saúde de Braga, E. P. E.
Braga, 4710-243, Portugal
Caledial - Centro de Hemodiálise de Gaia
Canelas-V.N.Gaia, 4410-313, Portugal
NephroCare Carregado
Carregado, 2580-588, Portugal
Nephrocare Faro
Faro, 8055-546, Portugal
Centro Hospitalar e Universitário de Lisboa Centra
Lisbon, 1050-099, Portugal
Fresenius Medical Care - NephroCare - Unidade de Hemodialise do Restelo
Lisbon, 1400-195, Portugal
Unidade Local de Saúde de Loures -Odivelas, E. P. E.
Loures, 2674-514, Portugal
Unidade Local de Saúde de São José, E. P. E.
Oeiras, 2790, Portugal
Unidade Local de Saúde de Santo António, E. P. E.
Porto, 4099-001, Portugal
Fresenius NephroCare
Porto, 4470-235, Portugal
Unidade Local de Saúde do Médio Tejo, E. P. E.
Torres Novas, 2354-754, Portugal
Unidade Local de Saúde do Estuário do Tejo, E. P. E.
Vila Franca de Xira, 2600-009, Portugal
Legacy Senior Living
Humacao, 791, Puerto Rico
Centrul de Dializa Fresenius NephroCare Brasov
Brasov, 500152, Romania
SC International Healthcare Systems SA - IHS Sf. Ioan Dialysis Center
Bucharest, 042122, Romania
Centrul De Nefrologie si Dializa DIAVERUM SPLAI
Bucharest, 060044, Romania
Centrul de Dializa Fresenius NephroCare Bucaresti
Bucharest, 203512, Romania
Fundeni Clinical Institute
Bucharest, 22328, Romania
Centrul de Nefrologie si Dializa DIAVERUM Sema Parc
Bucharest, 60044, Romania
Centrul de Nefrologie si Dializa Diaverum Fundeni
Bucharest, 77085, Romania
Centrul de Dializa Fresenius NephroCare Cluj
Cluj-Napoca, 400505, Romania
Centrul de Dializa Fresenius NephroCare Constanta
Constanța, 900001, Romania
Spitalul Clinic Judetean de Urgenta Sf. Apostol Andrei Constanta (Emergency Clinic Hospital Constanta)
Constanța, 900591, Romania
Centrul de Nefrologie si Dializa Diaverum Craiova
Craiova, 200349, Romania
Spitalul Judetean de Urgenta Deva
Deva, 33081, Romania
Spitalul Clinic -Dr. C.I. Parhon - Iasi
Iași, 700503, Romania
Spitalul Clinic Municipal Dr. Gavril Curteanu Oradea
Oradea, 410057, Romania
Centrul de Dializa Fresenius NephroCare Ploiesti
Ploieşti, 100551, Romania
Spital Judetean de Urgenta Satu Mare
Satu Mare, 440055, Romania
Centrul Medical de Nefrologie si Dializa Diaverum Targu Mures
Târgu Mureş, 540487, Romania
Nefrologicka ambulancia Levice - FMC dialyzacne sluzby, s.r.o.
Levice, 934 01, Slovakia
LC-REN s.r.o.
Lučenec, 98401, Slovakia
Biodial, s.r.o.
Púchov, 020 01, Slovakia
SMG - SNU Boramae Medical Center
Ilsan-gu, Seoul, 7061, South Korea
Hallym University Sacred Heart Hospital
Anyang-si, 14068, South Korea
Keimyung University Dongsan Medical Center
Daegu, 42601, South Korea
Gangnam Severance Hospital
Gangnam-gu, 6273, South Korea
National Health Insurance Service - Ilsan Hospital
Goyang-si, 10444, South Korea
Hanyang University Guri Hospital
Guri-si, 11923, South Korea
Konkuk University Medical Center
Gwangju, 5030, South Korea
Seoul National University Hospital
Seoul, 03080, South Korea
Severance Hospital, Yonsei University
Seoul, 03722, South Korea
Yonsei University - Wonju Severance Christian Hospital
Wŏnju, 26426, South Korea
Centro de dialisis Alcobendas
Alcobendas, 28100, Spain
Hospital Universitari de Bellvitge (IDIBELL)
Barcelona, 08907, Spain
Hospital Universitario Valle de Hebron
Barcelona, 8035, Spain
University Hospital Reina Sofía
Córdoba, 14005, Spain
Hospital Universitari de Girona Dr Josep Trueta, (Avitum)
Girona, 17007, Spain
Hospital Universitario Virgen de las Nieves
Granada, 18014, Spain
Universidad de Alcala (UAH)
Guadalajara, 19002, Spain
Hospital Universitari Arnau de Vilanova
Lleida, 25198, Spain
Hospital Universitario de La Princesa
Madrid, 28006, Spain
Universitario Gregorio Marañón
Madrid, 28007, Spain
Hospital Clínico San Carlos
Madrid, 28040, Spain
Hospital Universitario Fundacion Jimenez Diaz
Madrid, 28040, Spain
Hospital Universitario Príncipe de Asturias
Madrid, 28806, Spain
Hospital de Manises
Manises, 46940, Spain
Hospital Universitari Son Espases
Palma de Mallorca, 7120, Spain
CHUS - H. Clinico U. de Santiago
Santiago de Compostela, 15706, Spain
Hospital Universitario Virgen de la Macarena
Seville, 41009, Spain
Fresenius Medical Care Centro de Diálisis Terrassa
Terrassa, 8223, Spain
Hospital Clinico Universitario - Valencia
Valencia, 46010, Spain
Centro Hospital Universitario Dr. Preset
Valencia, 46017, Spain
Hospital Universitari i Politècnic La Fe
Valencia, 46026, Spain
Karolinska Huddinge
Huddinge, 14186, Sweden
Region Stockholm-SLSO
Stockholm, 113 65, Sweden
Uppsala Universitet - Akademiska Sjukhuset
Uppsala, 75185, Sweden
Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, 807, Taiwan
Far Eastern Memorial Hospital
New Taipei City, 220216, Taiwan
Taipei Medical University Shuang Ho Hospital
New Taipei City, 235041, Taiwan
Taichung Veterans General Hospital
Taichung, 40705, Taiwan
Taipei Medical University - Taipei Medical University Hospital
Taipei, 110, Taiwan
Maharat Nakhon Ratchasima Hospital
Amphoe Mueang, 30000, Thailand
Ramathibodi Hospital
Bangkok, 10400, Thailand
Chiang Mai University
Chiang Mai, 50200, Thailand
Hacettepe University,Faculty of Medicine
Ankara, 6230, Turkey (Türkiye)
Akdeniz University Medical Faculty Hospital
Antalya, 7070, Turkey (Türkiye)
Ondokuz Mayis Üniversitesi
Atakum, 55280, Turkey (Türkiye)
İstanbul Bakirköy Dr.Sadi Konuk Eğitim Araştirma Hastanesi
Bakırköy, 34147, Turkey (Türkiye)
Ege University Hospital
Bornova, 35100, Turkey (Türkiye)
Trakya Üniversitesi Tıp Fakültesi
Edirne, 22030, Turkey (Türkiye)
Kocaeli University, Medical Faculty, Division of Nephrology
İzmit, 41000, Turkey (Türkiye)
Kahramanmaras Sutcu Imam University - Tip Fakultesi (Kahramanmaras Sutcu Imam University Faculty of Medicine)
Kahramanmaraş, 46040, Turkey (Türkiye)
Malatya Education and Research Hospital
Yeşilyurt, 44000, Turkey (Türkiye)
University Hospitals Birmingham NHS Foundation Trust - Birmingham Heartlands Hospital (BHH)
Birmingham, B9 5SS, United Kingdom
Bradford Teaching Hospitals NHS Foundation Trust
Bradford, BD9 6RJ, United Kingdom
University Hospital Coventry and Warwickshire
Coventry, CV2 2DX, United Kingdom
University Hospitals of Derby and Burton NHS Foundation Trust - Royal Derby Hospital
Derby, DE22 3NE, United Kingdom
Dorset County Hospital NHS Foundation Trust - Dorset County Hospital (DCH)
Dorchester, DT1 2JY, United Kingdom
Royal Liverpool University Hospital
Liverpool, L7 8XP, United Kingdom
William Harvey Research Institute ; Barts Health NHS Trust - The Royal London Hospital
London, E1 1BB, United Kingdom
King´s College NHS Trust
London, SE5 9RS, United Kingdom
St George's University Hospitals NHS Foundation Trust - St G
London, SW17 0QT, United Kingdom
Hammersmith Hospital Imperial College Healthcare NHS Trust -Hammersmith Hospital - West London Renal and Transplant Centre
London, W12 0HS, United Kingdom
Altnagelvin Area Hospital
Londonderry, BT47 6SB, United Kingdom
Northern Care Alliance NHS Foundation Trust - Salford Royal NHS Foundation Trust-Salford Care Organisation
Salford, M6 8HD, United Kingdom
The Shrewsbury and Telford Hospital NHS Trust (SaTH) - Royal Shrewsbury Hospital
Shrewsbury, SY3 8XQ, United Kingdom
Royal Stoke University Hospital
Stoke-on-Trent, ST4 6QG, United Kingdom
The Royal Wolverhampton NHS Trust - New Cross Hospital
Wolverhampton, WV10 0QP, United Kingdom
Related Publications (1)
Chertow GM, Chang AM, Felker GM, Heise M, Velkoska E, Fellstrom B, Charytan DM, Clementi R, Gibson CM, Goodman SG, Jardine M, Levin A, Lokhnygina Y, Mears J, Mehran R, Stenvinkel P, Wang AY, Wheeler DC, Zoccali C, Ridker PM, Mahaffey KW, Tricoci P, Wolf M. IL-6 inhibition with clazakizumab in patients receiving maintenance dialysis: a randomized phase 2b trial. Nat Med. 2024 Aug;30(8):2328-2336. doi: 10.1038/s41591-024-03043-1. Epub 2024 May 25.
PMID: 38796655DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Study Director
CSL Behring LLC
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- SUPPORTIVE CARE
- Intervention Model
- PARALLEL
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 29, 2022
First Posted
August 3, 2022
Study Start
October 21, 2022
Primary Completion (Estimated)
May 22, 2029
Study Completion (Estimated)
May 22, 2029
Last Updated
May 1, 2026
Record last verified: 2026-04
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP
- Time Frame
- Requests for IPD will generally be considered once review by major regulatory authorities (ie FDA, EMA) is complete and the primary publication is available.
- Access Criteria
- Proposed research should seek to answer a previously unanswered important medical or scientific question. Applicable country specific privacy and other laws and regulations will be considered and may prevent sharing of IPD. If the request is approved and the researcher has executed an appropriate data sharing agreement, IPD that has been appropriately anonymized will be available.
CSL will consider on a case-by-case basis requests to share Individual Patient Data (IPD) with external bona-fide, qualified scientific and medical researchers. For information on the process and requirements for submitting a voluntary data sharing request for IPD, please contact CSL at clinicaltrials@cslbehring.com.