Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 30/100

Failure Rate

13.5%

29 terminated/withdrawn out of 215 trials

Success Rate

83.7%

-2.8% vs industry average

Late-Stage Pipeline

36%

77 trials in Phase 3/4

Results Transparency

52%

77 of 149 completed trials have results

Key Signals

20 recruiting77 with results21 terminated8 withdrawn

Enrollment Performance

Analytics

Phase 3
56(32.2%)
Phase 2
52(29.9%)
Phase 1
33(19.0%)
Phase 4
21(12.1%)
N/A
12(6.9%)
174Total
Phase 3(56)
Phase 2(52)
Phase 1(33)
Phase 4(21)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (215)

Showing 20 of 215 trials
NCT05193552Phase 4Recruiting

Usage of Spirometry in Managing IgG Therapy in CVID With Airway Disease

Role: collaborator

NCT05485961Phase 2Recruiting

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

Role: lead

NCT06699849Phase 2Recruiting

Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis

Role: lead

NCT06738485Phase 3Active Not Recruiting

Recombinant Single-chain Factor VIII (rVIII-SingleChain) in Chinese Participants With Hemophilia A Previously Treated With FVIII Products

Role: lead

NCT06050993Completed

Effects of Platelet Mimicking Nanoparticles in Patients With Cirrhosis

Role: collaborator

NCT07076446Phase 4Active Not Recruiting

An Open-label, Multicenter Study to Assess the Pharmacokinetics (PK), Safety, and Tolerability of Subcutaneous IgPro20 in Immunoglobulin (IG) Treatment-naïve Participants With Primary Immunodeficiency (PID)

Role: lead

NCT03805789Phase 2Completed

The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant

Role: lead

NCT02972281Not ApplicableCompleted

Systematic Search for Primary Immunodeficiency in Adults With Infections

Role: collaborator

NCT07080905Phase 3Recruiting

Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

Role: lead

NCT07094087Phase 3Recruiting

Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

Role: lead

NCT06524739Phase 3Terminated

Double-blind, Randomized, Placebo-controlled Study Evaluating Efficacy and Safety of IgPro20 in Post-COVID-19 POTS

Role: lead

NCT06806657Phase 4Recruiting

Safety Study in Subjects ≥ 12 Years of Age With Hereditary Angioedema Switching to Garadacimab

Role: lead

NCT03569891Phase 3Completed

HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients

Role: lead

NCT07332091Phase 2Recruiting

Efficacy and Safety of Vamifeport in Adult Participants With Homeostatic Iron Regulator Gene (HFE)-Related Hereditary Hemochromatosis

Role: lead

NCT07001280Recruiting

A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)

Role: lead

NCT06003387Phase 3Recruiting

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

Role: lead

NCT06617897Phase 3Recruiting

Phase 3 Study of Fibrinogen Concentrate (CSL511) in Subjects With Pseudomyxoma Peritonei Undergoing Cytoreductive Surgery

Role: lead

NCT07326592Phase 4Not Yet Recruiting

Phase 4, Double-blind Study Evaluating the Response on Computed Tomography (CT) Lung Density Decline Rates of Respreeza / Zemaira Weekly for 3 Years in Adults With alpha1 Antitrypsin Deficiency (AATD)

Role: lead

NCT05727384Phase 2Active Not Recruiting

Improving Physical Function in Older Adults Using an Anti-inflammation Drug: The RIGHT Study

Role: collaborator

NCT07224360Phase 2Recruiting

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

Role: lead