NCT05479851

Brief Summary

The purpose of this study is to investigate what patients think about increasing provision of advice about how to detect cancer early and how to reduce their future cancer risk after they are discharged from a two-week wait referral pathway for suspected cancer. This study will send a postal survey to patients living in the UK who were recently referred onto the suspected cancer pathway and were discharged without a cancer diagnosis (i.e. a negative diagnosis). Patients will be presented with different types of support and patients' views of the burden, benefits, understanding and perceived effectiveness of each one will be measured.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
406

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 19, 2022

Completed
3 months until next milestone

First Posted

Study publicly available on registry

July 29, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

October 7, 2022

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2023

Completed
Last Updated

June 15, 2023

Status Verified

June 1, 2023

Enrollment Period

6 months

First QC Date

April 19, 2022

Last Update Submit

June 13, 2023

Conditions

Cancer

Keywords

Cancer early diagnosisCancer awarenessCancer risk reduction behaviourHealth Behaviour

Outcome Measures

Primary Outcomes (1)

  • Participants' prospective acceptability ratings of different types of cancer advice and support interventions using a thirteen-item scale

    Prospective acceptability (perceived acceptability prior to intervention participation) of different cancer advice and support interventions, will be compared using scores obtained from a 13-item scale reflecting the domains of the Theoretical Framework of Acceptability (Scott et al 2021).

    cross sectional questionnaire to be completed 1-3 months after urgent referral

Secondary Outcomes (1)

  • Proportions of participants willing to receive each type of advice/ support, after discharge from a two week wait (urgent referral) pathway

    cross sectional questionnaire to be completed 1-3 months after urgent referral

Study Arms (1)

UK National Health Service Patient Postal Survey Participants

Patients who have agreed to participate in the study after receiving a postal invitation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults \>18 years old who have been referred through the two-week wait pathway for suspected cancer, and who have received a negative diagnosis (i.e. informed of a 'ruling out of cancer' according to the new 28-day faster diagnosis standard).

You may qualify if:

  • Adults \>18 years old
  • Referred through the two-week wait pathway for suspected cancer
  • Received a negative diagnosis (i.e. informed of a 'ruling out of cancer' according to the new 28-day faster diagnosis standard) within the past 1-3 months

You may not qualify if:

  • Adults who have been diagnosed with cancer
  • Adults who have not yet been informed of their results from their urgent referral

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

King's College London

London, Surrey, RH8 0NR, United Kingdom

Location

Related Publications (3)

  • Scott SE, Rauf B, Waller J. "Whilst you are here..." Acceptability of providing advice about screening and early detection of other cancers as part of the breast cancer screening programme. Health Expect. 2021 Oct;24(5):1868-1878. doi: 10.1111/hex.13330. Epub 2021 Aug 8.

    PMID: 34369071BACKGROUND

  • Stevens C, Vrinten C, Smith SG, Waller J, Beeken RJ. Acceptability of receiving lifestyle advice at cervical, breast and bowel cancer screening. Prev Med. 2019 Mar;120:19-25. doi: 10.1016/j.ypmed.2018.12.005. Epub 2018 Dec 19.

    PMID: 30578909BACKGROUND

  • Stevens C, Smith SG, Quaife SL, Vrinten C, Waller J, Beeken RJ. Interest in lifestyle advice at lung cancer screening: Determinants and preferences. Lung Cancer. 2019 Feb;128:1-5. doi: 10.1016/j.lungcan.2018.11.036. Epub 2018 Nov 27.

    PMID: 30642439BACKGROUND

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 19, 2022

First Posted

July 29, 2022

Study Start

October 7, 2022

Primary Completion

March 31, 2023

Study Completion

March 31, 2023

Last Updated

June 15, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will share

We will obtain consent for electronic copies of anonymised non-personally identifiable data (e.g. questionnaire responses) to be archived, shared and available for secondary analysis via a data sharing repository (e.g. King's College London (KCL) data repository). Data will be uploaded to the repository upon acceptance of publication or within 3 months of the end of the funding, whichever occurs earliest.

Time Frame
Data will be uploaded to the repository upon acceptance of publication or within 3 months of the end of the funding, whichever occurs earliest.
Access Criteria
Anonymous questionnaire data will be available for use via the repository by other researchers if they have further ethical approval to re-use the data.

Locations

GB(1)