NCT05025111

Brief Summary

This study is a clinical performance validation study to evaluate the performance of the Entia Liberty device. Patients undergoing routine venepuncture blood tests will be recruited to have an Entia Liberty test (by finger-prick) done on them by a trained healthcare professional. The results from that finger-prick test will be compared against the results from the routine venepuncture blood test (reference method) and subsequently, excess blood from the routine venepuncture test will be run on another Entia Liberty device in the laboratory. All three results (Entia Liberty capillary, Entia Liberty venous and gold standard venous) will be compared against each other to prove Entia Liberty's performance claims.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Sep 2022

Shorter than P25 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2021

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 27, 2021

Completed
1 year until next milestone

Study Start

First participant enrolled

September 12, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 26, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 26, 2022

Completed
Last Updated

January 27, 2023

Status Verified

January 1, 2023

Enrollment Period

1 month

First QC Date

August 26, 2021

Last Update Submit

January 26, 2023

Conditions

Outcome Measures

Primary Outcomes (3)

  • To obtain/validate the value of the total error of the Entia Liberty device.

    The dataset from this study will provide evidence to support the device's performance claims.

    3 months

  • To obtain/validate the value of the linearity of the Entia Liberty device.

    The dataset from this study will provide evidence to support the device's performance claims.

    3 months

  • To obtain/validate the value of the bias of the Entia Liberty device.

    The dataset from this study will provide evidence to support the device's performance claims.

    3 months

Interventions

Home monitoring device

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Participants will be recruited from the outpatients clinic at the Christie, while they are waiting for their blood tests.

You may qualify if:

  • Age \>18 years old at the time of study entry
  • Currently receiving standard of care systemic anti- cancer therapy (chemotherapy, immunotherapy, endocrine and targeted therapy) for solid organ malignancy and has received at least one cycle.
  • Scheduled to be undergoing routine venous laboratory blood tests as part of standard of care
  • Can provide written informed consent
  • Blood samples collected and stored in K2-EDTA vacutainers only

You may not qualify if:

  • Known inherited or acquired bleeding disorder
  • History of haematological malignancy
  • Known poorly controlled anti-coagulation
  • Inadequate use and understanding of the English language, requiring a translator

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

The Christie NHS Foundation Trust

Manchester, United Kingdom

Location

Royal Albert Edward Infirmary

Wigan, United Kingdom

Location

MeSH Terms

Conditions

Neoplasms

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2021

First Posted

August 27, 2021

Study Start

September 12, 2022

Primary Completion

October 26, 2022

Study Completion

October 26, 2022

Last Updated

January 27, 2023

Record last verified: 2023-01

Locations