A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products
VOYAGER
Real-World, Long-Term Data Collection to Gain Clinical Insights Into Roche Ophthalmology Products (VOYAGER STUDY)
1 other identifier
observational
6,000
29 countries
299
Brief Summary
The VOYAGER study is a primary data collection, non-interventional, prospective, multinational, multicenter study. It is designed to collect real-world, long-term data to explore long-term effectiveness, safety, clinical insights, treatment patterns, and factors driving the treatment decisions among patients being treated with specified Roche ophthalmology products in approved retinal indications (Faricimab for neovascular age-related macular degeneration \[nAMD\], diabetic macular edema \[DME\], and retinal vein occlusion; Port Delivery System with Ranibizumab for nAMD) in routine clinical practice. This study will not provide or make recommendations on use of any products including Roche products; treatment decisions will be determined by the treating physician and must be made independently to the decision to participate in this study. Participation in this study will not change or influence a patient's standard of care in any way.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2022
Longer than P75 for all trials
299 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 25, 2022
CompletedFirst Posted
Study publicly available on registry
July 27, 2022
CompletedStudy Start
First participant enrolled
November 21, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 30, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
November 30, 2027
March 16, 2026
March 1, 2026
4 years
July 25, 2022
March 13, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Change in Visual Acuity from Baseline at 1 Year, per Approved Retinal Indication and Product
Visual acuity will be collected as measured per local practice and then will be converted to the approximate ETDRS letter score.
Baseline and 1 year
Secondary Outcomes (17)
Change in Visual Acuity from Baseline Over Time, per Approved Retinal Indication and Product
Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
Percentage of Eyes on Each Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other) Over Time, per Approved Retinal Indication and Product
Baseline, 3, 6, and 12 months, and annually thereafter (up to 5 years)
Number of Treatments Over Time, per Approved Retinal Indication and Product
At 3, 6, and 12 months, and annually thereafter (up to 5 years)
Cumulative Time Spent on Each Treatment per Eye, Overall and per Treatment Regimen (Fixed, Treat-and-Extend, As Needed, or Other), per Approved Retinal Indication and Product
From Baseline until end of study (up to 5 years)
Percentage of Eyes with Treatment Switch by Reason for Switch Over Time, per Approved Retinal Indication and Product
At 3, 6, and 12 months, and annually thereafter (up to 5 years)
- +12 more secondary outcomes
Study Arms (5)
Cohort 1: Faricimab for nAMD
Cohort 2: Faricimab for DME
Cohort 3: Port Delivery System with Ranibizumab for nAMD
Cohort 4: Faricimab for BRVO
Cohort 5: Faricimab for CRVO/HRVO
Interventions
Faricimab will be administered as per local clinical practice and local labeling.
The port delivery system with ranibizumab will be administered as per local clinical practice and local labeling.
Eligibility Criteria
Patients being treated with specified Roche ophthalmology products approved in retinal indications in real-world, routine clinical practice.
You may qualify if:
- \. Have provided informed consent, as required per local regulations 2.a) Adult patient, as defined by local regulations and local product label, who is newly initiating treatment (or initiated treatment in the previous visit) with a specified approved Roche ophthalmology product in retinal indication of interest for this study in at least one eye, according to the investigator's discretion in routine clinical practice; OR 2.b) Adult patient, as defined by local regulations and local product label, who is continuing treatment with any specified approved Roche ophthalmology product in retinal indication of interest for this study in at least one eye after initiating that treatment in a Roche interventional trial.
You may not qualify if:
- \. Concomitant participation of the patient in an investigational ophthalmology clinical trial that includes receipt of any investigational drug or procedure within the last 28 days prior to enrollment (this restriction does not apply to patients who are rolling over from Roche interventional studies and continuing treatment with any specified approved Roche ophthalmology product in retinal indication of interest for this study)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (299)
Retinal Research Institute, LLC
Phoenix, Arizona, 85014, United States
California Eye Specialists Medical group Inc.
Pasadena, California, 91107, United States
Retinal Consultants Medical Group
Sacramento, California, 95825, United States
Advanced Research
Coral Springs, Florida, 33067, United States
Retina Specialty Institute
Pensacola, Florida, 32503, United States
University Retina and Macula Associates, PC
Lemont, Illinois, 60439, United States
Springfield Clinic, Llp
Springfield, Illinois, 62703, United States
Retina Associates of Kentucky
Lexington, Kentucky, 40509, United States
Cumberland Valley Retina Consultants PC
Hagerstown, Maryland, 21740, United States
Associated Retinal Consultants PC
Royal Oak, Michigan, 48073, United States
Erie Retinal Surgery
Erie, Pennsylvania, 16507, United States
Tennessee Retina PC
Nashville, Tennessee, 37203, United States
Brown Retina Institute
San Antonio, Texas, 78251-4551, United States
Retina Center of Texas
Southlake, Texas, 76092-1352, United States
University of Utah, John Moran Eye Center
Salt Lake City, Utah, 84132, United States
Piedmont Eye Center
Lynchburg, Virginia, 24502, United States
Wagner Macula and Retina Center
Norfolk, Virginia, 23502-3933, United States
Spokane Eye Clinical Research
Spokane, Washington, 99204, United States
Salud Ocular
Ciudad Autonoma de Buenos Aires, Buenos Aires, C1056, Argentina
Instituto Oftalmologico de Buenos Aires S.A.
Buenos Aires, C1056AAN, Argentina
Centro Oftalmologico Dr. Charles S.A.
Ciudad Autonoma Buenos Aires, C1116ABA, Argentina
Centro Privado de Ojos Romagosa S.A
Córdoba, 5000, Argentina
CEO Centro de Especialidades Oftalmologicas Tucuman
San Miguel de Tucumán, T4000IOA, Argentina
Retina and Macula Specialists
Hurstville, New South Wales, 2220, Australia
Sydney West Retina
Westmead, New South Wales, 2145, Australia
Sunshine Coast University Hospital
Geebung, Queensland, 4034, Australia
Centre For Eye Research Australia
East Melbourne, Victoria, 3002, Australia
Cabrini Hospital Malvern
Melbourne, Victoria, 3144, Australia
Retina Specialists Victoria
Rowville, Victoria, 3178, Australia
Lions Outback Vision Service in Broome
Broome, Western Australia, 6725, Australia
The Lions Eye Institute
Nedlands, Western Australia, 6009, Australia
Medical Center for Eye Health ? Focus Ltd
Sofia, 1303, Bulgaria
Specialized Eye Hospital Pentagram
Sofia, 1319, Bulgaria
Specialized Hospital for Active Treatment of Ophthalmologic Diseases ?Zora?, OOD
Sofia, 1784, Bulgaria
Eye Clinic St. Petka - Varna
Varna, 9000, Bulgaria
SHEDAT - Varna EOOD
Varna, 9002, Bulgaria
Retina Surgical Associates
New Westminster, British Columbia, V3L 5H1, Canada
Toronto Retina Institute
Don Mills, Ontario, M1E 4A7, Canada
St Joseph's Centre for Mountain Health Services
Hamilton, Ontario, L9C 0E3, Canada
St. Joseph's Health Care - London
London, Ontario, N6A 4V2, Canada
Retina Institute of Ottawa
Ottawa, Ontario, K2B 7E9, Canada
Clarity eye Institute
Vaughan, Ontario, L4K 0J4, Canada
Institut De L'Oeil Des Laurentides
Boisbriand, Quebec, J7H 0E8, Canada
Clinique d'ophtalmologie et de Retine de l'est
Montreal, Quebec, H1TY 0E2, Canada
Eye Health MD (Opthalmology)
Montreal, Quebec, H4P 2S4, Canada
Retina MD Clinic
Sainte-Catherine, Quebec, J5C 1V9, Canada
Centre Oculaire de Quebec
Québec, G1V 1T6, Canada
Red Salud UC Christus
Santiago, Santiago Metropolitan, 7620002, Chile
Centro de la Vision
Las Condes, 7600830, Chile
General Hospital Karlovac
Karlovac, 47000, Croatia
Clinical Hospital Centre Osijek
Osijek, 31000, Croatia
Clinical Hospital Centre Rijeka
Rijeka, 51000, Croatia
Special Hospital for Ophthalmology Svjetlost
Zagreb, 10000, Croatia
University Hospital Center Zagreb
Zagreb, 10000, Croatia
Nemocnice Pardubickeho kraje a.s.
Pardubice, 530 03, Czechia
Fakultni nemocnice Kralovske Vinohrady
Prague, 100 34, Czechia
Tomas Bata Regional Hospital
Zlín, 762 75, Czechia
Ålborg Universitets Hospital
Aalborg, 9100, Denmark
Rigshospitalet Glostrup
Glostrup Municipality, 2600, Denmark
Sjllands Universitetshospital
Roskilde, 4000, Denmark
Egypt Air Hospital
Cairo, 0000, Egypt
Centre Ophtalmologique Maison-Rouge
Strasbourg, Bas Rhin, 67000, France
CH St Joseph
Marseille, Bouches Du Rh(ne, 13285, France
CHU Dijon - Hopital Francois Mitterrand
Dijon, Cte-d'Or, 21079, France
Groupe Hospitalier Pellegrin
Bordeaux, Gironde, 33800, France
CHU de Nantes - Hotel Dieu
Nantes, Loire Atlantique, 44093, France
Institut Ophtalmologique De l Ouest Jules Verne
Nantes, Paris, 44300, France
CHU de St-Etienne - Hopital Nord
Saint-Étienne-de-Montluc, Pays de la Loire Region, 42055, France
Hopital Edouard Herriot - CHU Lyon
Lyon, Rhone, 69003, France
Centre Hospitalier de la Croix Rousse
Lyon, Rhone, 69004, France
Clinique Mathilde
Rouen, Seine Maritime, 76000, France
Hopital Avicenne
Bobigny, Seine Saint Denis, 93000, France
CHU Amiens Picardie, Centre de Recherche Clinique
Amiens, Somme, 80080, France
Centre Hospitalier de Versailles
Le Chesnay, Yvelines, 78150, France
Aix Vision
Aix-en-Provence, 13090, France
Centre Rétine Gallien
Bordeaux, 33000, France
Centre Hospitalier Intercommunal de Créteil
Créteil, 94010, France
Clinique du Val d'Ouest- Institut Rhône Alpin
Écully, 69130, France
Clinique des Yeux Bordeaux
Floirac, 33270, France
Centre d'Ophtalmologie
Fontainebleau, 77300, France
Centre Optha Du Dauphine
Grenoble, 38000, France
Hôpital Saint-Louis - La Rochelle
La Rochelle, 17019, France
Visiopole Private Practice
Lagord, 17140, France
Centre Ophtalmologique Rabelais
Lyon, 69002, France
Centre Ophtalmologique Kleber
Lyon, 69006, France
Centre Monticelli Paradis d Ophtalmologie
Marseille, 13008, France
Clinique de Montargis
Montargis, 45200, France
Clinique Honore Cave
Montauban, 82000, France
Alpes Retine
Montbonnot-Saint-Martin, 38330, France
Centre Des Arceaux
Montpellier, 34000, France
CHU Nice - Hôpital Saint Roch
Nice, 06006, France
Centre Ophtalmologique de L'Odeon
Paris, 75006, France
Centre Ophtalmologique d?Imagerie et de Laser
Paris, 75015, France
CHU Poitiers - Hôpital la Milétrie
Poitiers, 86021, France
Centre St Exupery
Saint-Cyr-sur-Loire, 37540, France
Institut Sourdille
Saint-Herblain, 44800, France
Clinique de l'Union
Saint-Jean, 31240, France
Chu Toulouse
Toulouse, 31059, France
Augenklinik des Universitaetsklinikums Erlangen
Erlangen, Bavaria, 91054, Germany
Medical Eye Research Xpertx Institut gGmbH
Trier, Bavaria, 86438, Germany
Private Practice of Dr. Astrid Sader Moritz
Würzburg, Bavaria, 97080, Germany
Carl-Thiem-Klinikum Cottbus gGmbH - Augenklinik
Cottbus, Brandenburg, 03048, Germany
Klinikum Ernst von Bergmann gGmbH
Potsdam, Brandenburg, 14467, Germany
Augenzentrum Prof. Koch GmbH
Frankfurt am Main, Hesse, 60549, Germany
Universitaetsklinikum Frankfurt Goethe-Universitaet
Frankfurt am Main, Hesse, 60590, Germany
Medizinische Hochschule Hannover
Hanover, Lower Saxony, 30625, Germany
Universitaetsmedizin Greifswald
Greifswald, Mecklenburg-Vorpommern, 17475, Germany
Apotheke am Klinikum Ludwigshafen
Ludwigshafen am Rhein, Rhineland-Palatinate, 67063, Germany
Universitaetsklinikum Carl Gustav Carus TU Dresden
Dresden, Saxony, 01307, Germany
Universitaetsklinikum Leipzig
Leipzig, Saxony, 04103, Germany
Augenzentrum Erzgebirge
Zschopau, Saxony, 09405, Germany
Martin-Luther-Universitaet Halle-Wittenberg - Staedtisches Klinikum Dessau (SKD)
Dessau, Saxony-Anhalt, 06847, Germany
Universitaetsklinikum Schleswig-Holstein - Campus Luebeck
Lübeck, Schleswig-Holstein, 23538, Germany
St. Gertrauden Krankenhaus Berlin, Augenheilkunde
Berlin, 10713, Germany
Vivantes Klinikum Neukoelln
Berlin, 12351, Germany
Klinikum Chemnitz gGmbH
Chemnitz, 09116, Germany
Universitaetsklinikum Koeln
Cologne, Koeln, Germany
Universitaetsklinikum Halle (Saale)
Halle, 06120, Germany
Universitaetsklinikum Heidelberg
Heidelberg, 69120, Germany
Universitätsklinikum Mannheim
Mannheim, 68305, Germany
Praxis Dr. Amin Gamael
Rostock, 18057, Germany
Universitaetsaugenklinik Rostock
Rostock, 18057, Germany
Knappschaftskrankenhaus Sulzbach
Sulzbach, 66280, Germany
Grantham Hospital
Hong Kong, 00000, Hong Kong
Hong Kong Eye Hospital
Kowloon, 000000, Hong Kong
Rambam Health Care Campus
Haifa, 31096, Israel
Wolfson Medical Center
Holon, 58100, Israel
Hadassah
Jerusalem, 9112001, Israel
Meir Medical Center
Kfar Saba, 4428164, Israel
Rabin MC
Petah Tikva, 49100, Israel
Tel-Aviv Sourasky Medical Center
Tel Aviv, 6423906, Israel
Assuta Hashalom Medical Center
Tel Aviv, 6789140, Israel
Ospedale Clinicizzato SS. Annunziata
Chieti, Abruzzo, 66100, Italy
Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari
Bari, Apulia, 70124, Italy
Azienda Ospedaliero Universitaria Mater Domini
Catanzaro, Calabria, 88100, Italy
Ospedale Monaldi - AORN dei Colli
Naples, Campania, 80131, Italy
Azienda Ospedaliera di Udine Ospedale S. Maria della Misericordia
Udine, Friuli Venezia Giulia, 33100, Italy
Fondazione Ptv Policlinico Tor Vergata
Rome, Lazio, 00133, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Rome, Lazio, 00168, Italy
G. B. Bietti Fondazione - IRCCS
Rome, Lazio, 00184, Italy
Azienda Ospedaliera Sant'Andrea-Universitr di Roma La Sapien
Rome, Lazio, 189, Italy
IRCCS Ospedale Policlinico San Martino
Genoa, Liguria, 16132, Italy
Humanitas Gavazzeni
Bergamo, Lombardy, 24125, Italy
Fondazione IRCCS CA? Granda Ospedale Maggiore Policlinico
Milan, Lombardy, 20122, Italy
Ospedale San Giuseppe Fatebenefratelli
Milan, Lombardy, 20123, Italy
Ospedale San Raffaele
Milan, Lombardy, 20132, Italy
Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo (San Paolo-Polo Universitario)
Milan, Lombardy, 20142, Italy
Azienda Socio Sanitaria Territoriale Fatebenefratelli (Presidio Ospedale Sacco)
Milan, Lombardy, Italy
Fondazione IRCCS - San Gerardo dei Tintori
Monza, Lombardy, 20900, Italy
Ente Ecclesiastico Ospedale Generale Regionale F Miulli
Acquaviva Delle Fonti, Piedmont, 70021, Italy
Ospedale Oftalmico
Turin, Piedmont, 10122, Italy
Città della Salute e della Scienza di Torino. Presidio Molinette
Turin, Piedmont, 10126, Italy
Ospedale Mauriziano Umberto I
Turin, Piedmont, 10128, Italy
Ospedale Di Sassuolo
Sassuolo, Sardinia, 41049, Italy
Azienda Ospedaliera Universitaria "Policlinico - Vittorio Emanuele" (Presidio Gaspare Rodolico)
Catania, Sicily, 95123, Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone
Palermo, Sicily, 90127, Italy
Azienda Ospedaliero Universitaria delle Marche
Ancona, The Marches, 60126, Italy
Aichi Medical University Hospital
Nagakute-shi, Aichi-ken, 480-1195, Japan
Nagoya University Hospital
Nagoya, Aichi-ken, 466-8560, Japan
Toho University Sakura Medical Center
Sakura-shi, Chiba, 285-8741, Japan
Hokkaido University Hospital
Sapporo, Hokkaido, 060-8648, Japan
Kobe University Hospital
Kobe, Hyōgo, 650-0017, Japan
Yokohama City University Medical Center
Yokohama, Kanagawa, 232-0024, Japan
Jichi Medical University Hospital
Shimotsuke-shi, Tochigi, 329-0498, Japan
Nihon University Hospital
Chiyoda-ku, Tokyo-To, 101-8309, Japan
Tokyo Medical University Hospital
Shinjuku-ku, Tokyo-To, 160-0023, Japan
Keio University Hospital
Shinjuku-ku, Tokyo-To, 160-8582, Japan
Chukyo Hospital
Aichi, 457-8510, Japan
Sugita Eye Hospital
Aichi, 460-0008, Japan
Nagoya City University Hospital
Aichi, 467-8602, Japan
Akita University Hospital
Akita, 010-8543, Japan
Chiba University Hospital
Chiba, 260-8677, Japan
Juntendo University Urayasu Hospital
Chiba, 279-0021, Japan
University of Yamanashi Hospital
Chuo-shi, 409-3898, Japan
Kyushu University Hospital
Fukuoka, 812-8582, Japan
Kurume University Hospital
Fukuoka, 830-0011, Japan
Gifu University Hospital
Gifu, 501-1194, Japan
Hiroshima University Hospital
Hiroshima, 734-8551, Japan
Sapporo City General Hospital
Hokkaido, 060-8604, Japan
University of Tsukuba Hospital
Ibaraki, 305-8576, Japan
Kozawa eye hospital and diabetes center
Ibaraki, 310-0845, Japan
Kagawa University Hospital
Kagawa, 761-0793, Japan
NHO Tokyo Medical Center
Meguro-ku, 152-8902, Japan
Mie University Hospital
Mie, 514-8507, Japan
Fukushima Medical University Hospital
Miyagi, 960-1295, Japan
Shinshu University Hospital
Nagano, 390-8621, Japan
Nagasaki University Hospital
Nagasaki, 852-8501, Japan
Japanese Red Cross Nagasaki Genbaku Hospital
Nagasaki, 852-8511, Japan
Tazuke-kofukai Medical Research Institute Kitano Hospital
Osaka, 530-8480, Japan
Osaka Metropolitan University Hospital
Osaka, 545-8586, Japan
Kansai Medical University Hospital
Osaka, 573-1191, Japan
Saitama Medical University Hospital
Saitama, 350-0451, Japan
Shiga University Of Medical Science Hospital
Shiga, 520-2192, Japan
Seirei Hamamatsu General Hospital
Shizuoka, 430-8558, Japan
Osaka University Hospital
Suita, 565-0871, Japan
Osaka Medical and Pharmaceutical University Hospital
Takatsuki-shi, 569-8686, Japan
Tokushima University Hospital
Tokushima, 770-8503, Japan
Juntendo University Hospital
Tokyo, 113-8431, Japan
Tokyo Women's Medical University Hospital
Tokyo, 162-8666, Japan
Kyorin University Hospital
Tokyo, 181-8611, Japan
Tokyo Medical University Hachioji Medical Center
Tokyo, 193-0998, Japan
Yamagata University Hospital
Yamagata, 990-9585, Japan
Yamaguchi University Hospital
Yamaguchi, 755-8505, Japan
University of Fukui Hospital
Yoshida-gun, 910-1193, Japan
Centrum Diagnostyki i Mikrochirurgii Oka LENS
Olsztyn, 10-424, Poland
Szpital im. Jozefa Strusia
Poznan, 61-285, Poland
Wojskowy Instytut Medyczny - Panstwowy Instytut Badawczy
Warsaw, 04-141, Poland
Szpital Specjalistyczny im Soko?owskiego
Wałbrzych, 58-309, Poland
Emanuelli Research and Development Center
Arecibo, 00612, Puerto Rico
King Khaled Eye Specialist Hospital
Riyadh, 12329, Saudi Arabia
National University Hospital
Singapore, 119228, Singapore
Singapore National Eye Centre
Singapore, 169608, Singapore
Eye & Retina Surgeons
Singapore, 248649, Singapore
Tan Tock Seng Hospital
Singapore, 308433, Singapore
Eagle Eye Centre
Singapore, 329563, Singapore
Univerzitetni Klinicni Center Ljubljana Ocesna Klinika
Ljubljana, 1000, Slovenia
CHA Bundang Medical Center, CHA University
Seongnam-si, Gyeonggi-do, 13496, South Korea
Yeungnam University Hospital
Daegu, 42415, South Korea
Hospital Universitari Son Espases
Palma de Mallorca, Balearic Islands, 07120, Spain
Fundacio Privada Hospital Asil de Granollers
Granollers, Barcelona, 08402, Spain
Hospital Universitari de Bellvitge
L'Hospitalet de Llobregat, Barcelona, 08907, Spain
Complejo Hospitalario Universitario de Ferrol
Ferrol, LA Coruna, 15405, Spain
Complejo Hospitalario Universitario de Santiago.
Santiago de Compostela, LA Coruna, 15706, Spain
Complejo Hospitalario San Millán y San Pedro De La Rioja
Logroño, La Rioja, 26006, Spain
Hospital Universitario Insular de Gran Canaria
Las Palmas de Gran Canaria, LAS Palmas, 35016, Spain
Hospital Costa del Sol
Marbella, Malaga, 29603, Spain
Hospital Xeral-Cies de Vigo
Vigo, Pontevedra, 36204, Spain
Hospital Universitario Nuestra Señora de la Candelaria
Santa Cruz de Tenerife, Tenerife, 38010, Spain
Hospital de Basurto
Bilbao, Vizcaya, 48013, Spain
Complejo Hospitalario Universitario de Albacete
Albacete, 02006, Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, 08025, Spain
Hospital Dos de Maig
Barcelona, 08025, Spain
Hospital Universitari Vall dHebron (CEMCAT)
Barcelona, 08035, Spain
Hospital Clinic de Barcelona
Barcelona, 08036, Spain
Complejo Asistencial Universitario de Burgos
Burgos, 09005, Spain
Hospital Universitario Puerta del Mar
Cadiz, 11009, Spain
Hospital Universitario Reina Sofia
Córdoba, 14004, Spain
Hospital Universitario Virgen de Las Nieves
Granada, 18012, Spain
Hospital Carlos Haya
Málaga, 29010, Spain
Hospital Universitario Virgen de La Arrixaca
Murcia, 30120, Spain
Hospital Universitario Virgen Del Rocio Sevila
Seville, 41013, Spain
Hospital Universitario Rio Hortega
Valladolid, 47012, Spain
Hospital Universitario Miguel Servet
Zaragoza, 50009, Spain
Lund University Hospital
Lund, 22185, Sweden
St Eriks Eye Hospital
Stockholm, 171 64, Sweden
Kantonsspital Aarau AG
Aarau, 5001, Switzerland
Universitätsspital Basel
Basel, 4031, Switzerland
Augenklinik am Lindenhofspital
Bern, 3007, Switzerland
Inselspital-Universitaetsspital Bern
Bern, 3010, Switzerland
Vista Augenklinik Binningen
Binningen, 4102, Switzerland
Hôpitaux Universitaires de Genève
Geneva, 1205, Switzerland
Hôpital ophtalmique Jules-Gonin
Lausanne, 1004, Switzerland
Swiss Visio Montchoisi
Lausanne, 1006, Switzerland
LUKS Spitalbetriebe AG
Lucerne, 6000, Switzerland
Ospedale Regionale di Lugano
Lugano, 6900, Switzerland
Pallas Klinik Olten
Olten, 4600, Switzerland
Kantonsspital St. Gallen
Sankt Gallen, 9007, Switzerland
Stadtspital Triemli
Zurich, 8055, Switzerland
Shin Kong Wu Ho-Su Memorial Hospital
Taipei, 111, Taiwan
Far Eastern Memorial Hospital
Taipei, 220, Taiwan
Chang Gung Memorial Hospital - Linkou
Taoyuan District, 333, Taiwan
King Chulalongkorn Memorial Hospital
Pathum Wan, Bangkok, 10330, Thailand
Srinagarind Hospital
Muang, Changwat Khon Kaen, 40002, Thailand
Songklanagarind Hospital
Hat Yai, Changwat Songkhla, 90110, Thailand
Metta Pracharak Hospital
Nakhon Pathom, RAI Khing, 73210, Thailand
Ramathibodi Hospital
Bangkok, 10400, Thailand
Siriraj Hospital
Bangkok, 10700, Thailand
Maharaj Nakorn Chiang Mai Hospital
Chiang Mai, 50200, Thailand
Burjeel Hopital
Abu Dhabi, 7400, United Arab Emirates
Medcare Eye Center - Dubai
Dubai, 251533, United Arab Emirates
Magrabi Eye Hospital
Dubai Healthcare City, 36267, United Arab Emirates
Bristol Eye Hospital
Bristol, Avon, BS1 2LX, United Kingdom
Bedford Hospital
Bedford, Bedfordshire, MK42 9DJ, United Kingdom
Torbay Hospital
Torquay, Devon, TQ2 7AA, United Kingdom
Hull Royal Infirmary
Hull, East Riding Of Yorkshire, HU3 2KZ, United Kingdom
Primary Care Centre
Colchester, Essex, CO4 5JR, United Kingdom
Gloucestershire Retinal Research Group
Gloucester, Gloucestershire, GL1 3NN, United Kingdom
Kings College Hospital
London, Greater London, SE5 9NU, United Kingdom
Maidstone Hospital
Maidstone, Kent, ME16 9QQ, United Kingdom
Royal Liverpool University Hospital
Liverpool, Merseyside, L7 8XP, United Kingdom
James Paget University Hospitals NHS Foundation Trust
Gorleston-on-Sea, Norfolk, NR31 6LA, United Kingdom
John Radcliffe Hospital
Headington, Oxfordshire, OX3 9DU, United Kingdom
Mater Infirmorum Hospital
Belfast, BT14 6AB, United Kingdom
University Hospitals Birmingham NHS Foundation Trust
Birmingham, B15 2TH, United Kingdom
Birmingham Midland Eye Centre
Birmingham, B18 7QH, United Kingdom
Bradford Royal Infirmary
Bradford, BD9 6RJ, United Kingdom
University Hospital of Wales
Cardiff, CF14 4XW, United Kingdom
Frimley Park Hospital
Frimley, GU16 7UJ, United Kingdom
North West London Hospitals NHS Trust
Harrow, HA1 3UJ, United Kingdom
St James University Hospital
Leeds, LS9 7TF, United Kingdom
Moorfields Eye Hospital
London, EC1V 2PD, United Kingdom
Royal Free Hospital
London, NW3 2QG, United Kingdom
Manchester Royal Eye Hospital
Manchester, M13 9WL, United Kingdom
James Cook University Hospital
Middlesbrough, TS4 3BW, United Kingdom
Royal Victoria Infirmary
Newcastle upon Tyne, NE1 4LP, United Kingdom
Royal Hallamshire Hospital
Sheffield, S10 2JF, United Kingdom
Southampton General Hospital
Southampton, SO16 6YD, United Kingdom
Sunderland Eye Infirmary
Sunderland, SR2 9HP, United Kingdom
The Royal Wolverhampton Hospitals NHS Trust
Wolverhampton, WV10 0QP, United Kingdom
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Clinical Trials
Hoffmann-La Roche
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 25, 2022
First Posted
July 27, 2022
Study Start
November 21, 2022
Primary Completion (Estimated)
November 30, 2026
Study Completion (Estimated)
November 30, 2027
Last Updated
March 16, 2026
Record last verified: 2026-03
Data Sharing
- IPD Sharing
- Will share
For eligible studies, qualified researchers may request access to individual patient level clinical data. See Roche's commitment to transparency of clinical study information here: https://go.roche.com/data\_sharing