Ultrasound-Guided Intermediate Versus Deep Cervical Plexus Block for Carotid Endarterectomy

NCT05353218 | Completed

• 1 other identifier: 2021/923
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Cervical plexus blocks are regional methods used in carotid endarterectomy. Cervical plexus blocks consist of three blocks: superficial, intermediate and deep. These three blocks can be used alone or combined. The aim of this study is to evaluate the effectiveness of ultrasound-guided intermediate and deed cervical plexus block in patients undergoing carotid endarterectomy.

Conditions

Anesthesia

Keywords

cervical plexus block; Endarterectomy, Carotid

Outcome Measures

Primary Outcomes (1)

• Number of patient needed supplemental local anesthetic

  If patients complain about pain above visual analog scale 3, 4ml 1% lidocaine is injected by surgeon.

  Intraoperative 2-3 hours

Secondary Outcomes (8)

• Amount of supplemental local anesthetic

  Intraoperative 2-3 hours

• Duration of blocks' application

  Up to 15 minutes

• Region where patient needs supplemental local anesthetic

  Intraoperative 2-3 hours

• Amount of remifentanil

  Intraoperative 2-3 hours

• Pain assessment

  Intraoperative 2-3 hours

Study Arms (2)

Group intermediate cervical plexus block (GI)

ACTIVE COMPARATOR

Patients anesthetized with intermediate cervical plexus block.

Procedure: Intermediate cervical plexus block

Group deep cervical plexus block (GD)

ACTIVE COMPARATOR

Patients anesthetized with deep cervical plexus block.

Procedure: Deep cervical plexus block

Interventions

Intermediate cervical plexus block PROCEDURE

Intermediate cervical plexus block will be applied in transverse plane using posterior approach at C4.

Group intermediate cervical plexus block (GI)

Deep cervical plexus block PROCEDURE

Deep cervical plexus block will be appliedin transverse plane using anterior approach at C2-3-4.

Group deep cervical plexus block (GD)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients scheduled for carotid endarterectom y surgery.

You may not qualify if:

• Local infection
• Previous ipsilateral surgery
• Radiotherapy
• Conversion to general anesthesia
• Known bleeding disorders
• Known allergy of local anesthetic

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Istanbul Faculty of Medicine

Istanbul, Turkey (Türkiye)

Location

Related Publications (1)

• Turhan O, Sivrikoz N, Canbolat N, Demirel EE, Altun D, Sungur Z. Ultrasound-guided intermediate versus deep cervical plexus block for carotid endarterectomy: a randomized controlled study. BMC Anesthesiol. 2025 Nov 21;25(1):581. doi: 10.1186/s12871-025-03460-w.

  PMID: 41272478 DERIVED

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist

Model Details: Randomized, Prospective

Study Record Dates

• First Submitted: April 24, 2022
• First Posted: April 29, 2022
• Study Start: June 7, 2022
• Primary Completion: January 15, 2023
• Study Completion: April 27, 2023
• Last Updated: April 28, 2023

Record last verified: 2023-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)