Comparison of Hypotension During Spinal Anaesthesia for C-section
To Tilt or Not to Tilt?: Comparison of Severity of Hypotension Between Supine and Left Tilt Position During Spinal Anesthesia for Elective C-section
1 other identifier
observational
38
1 country
1
Brief Summary
Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2022
CompletedFirst Submitted
Initial submission to the registry
June 16, 2022
CompletedFirst Posted
Study publicly available on registry
June 22, 2022
CompletedJune 22, 2022
June 1, 2022
2 months
June 16, 2022
June 16, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Group 1 - Supine Group
Systolic blood pressures decreased significantly in the supine group
December 2021 to February 2022
Group 2 - Left tilt Group
The decrease in the diastolic blood pressure was marginally significant in the left tilt group.
December 2021 to February 2022
Study Arms (2)
Supine group
Spinal anaesthesia was administered in sitting position and then supine position was maintained.
Left tilt group
Spinal anesthesia was administered in sitting position was then maintained on supine position until full anesthetic effect (motor and sensory loss) and then table was tilted 15 degrees to the left.
Eligibility Criteria
Participants after fulfilling the inclusion exclusion criteria were randomized by lottery method into two groups; supine group (Group 1) and left tilt group. (Group 2).
You may qualify if:
- Participants ≥ 18 years, undergoing Elective Caesarean Section for term singleton pregnancy, ASA I/II, were included after their consent for the participation of the study.
You may not qualify if:
- Participants with co-morbidities (Hypertension, diabetes mellitus, cardiovascular or cerebrovascular disease and a history of coagulation disorders), any contraindication to spinal anesthesia, with multiple pregnancy, pre-eclampsia, obesity (body mass index \> 30 kg.m2), intrauterine growth were excluded from the study.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Rawalpindi Medical University
Rawalpindi, Punjab Province, 46000, Pakistan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MBBS
Study Record Dates
First Submitted
June 16, 2022
First Posted
June 22, 2022
Study Start
December 1, 2021
Primary Completion
February 1, 2022
Study Completion
February 1, 2022
Last Updated
June 22, 2022
Record last verified: 2022-06