Dynamic Arterial Elastance to Predict Postural Change Induced Hypotension
Investigation on Dynamic Arterial Elastance as a Predictor of Hypotension Caused by the Positional Change From Supine to Prone (SuProne Study).
1 other identifier
observational
44
1 country
1
Brief Summary
During general anesthesia, hypotension might occur during positional change. It is reported that hypotension after positional change from supine to prone is mainly caused by the decrease in preload. The investigators aimed to investigate whether dynamic arterial elastance might predict hypotension associated with positional change from supine to prone.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Dec 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 14, 2021
CompletedFirst Posted
Study publicly available on registry
April 20, 2021
CompletedStudy Start
First participant enrolled
December 15, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 15, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
July 15, 2022
CompletedSeptember 23, 2022
September 1, 2022
7 months
April 14, 2021
September 21, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Dynamic arterial elastance before positional change
Dynamic arterial elastance, defined as the ratio of pulse pressure variance/stroke volume variance will be recorded 1 minute before positional change
1 minute before positional change
Study Arms (2)
Non-hypotensive
Mean blood pressure is maintained after positional change from supine to prone.
Hypotensive
Mean blood pressure decrease \< 20% after positional change from supine to prone.
Interventions
Patient is turned from supine to prone position for spine surgery
Eligibility Criteria
Patients who are scheduled for spine surgery and need positional change from supine to prone positioin.
You may qualify if:
- Patients planned for invasive arterial catheter insertion, undergoing elective spine surgery in prone position under general anesthesia
You may not qualify if:
- arrythmia
- pulmonary disease
- increased intracranial pressure
- decreased cardiac function (ejection fraction \< 50%)
- obesity (body mass index \> 40)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Kangbuk Samsung Hospital
Seoul, 03181, South Korea
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
April 14, 2021
First Posted
April 20, 2021
Study Start
December 15, 2021
Primary Completion
July 15, 2022
Study Completion
July 15, 2022
Last Updated
September 23, 2022
Record last verified: 2022-09