Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy
1 other identifier
observational
63
1 country
1
Brief Summary
Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Sep 2021
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 29, 2021
CompletedFirst Submitted
Initial submission to the registry
June 2, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 8, 2022
CompletedFirst Posted
Study publicly available on registry
June 14, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2022
CompletedJune 14, 2022
June 1, 2022
8 months
June 2, 2022
June 9, 2022
Conditions
Outcome Measures
Primary Outcomes (4)
Postoperative complications
dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak
a month after the surgery
Length of stay in the intensive care unit
Length of stay in the intensive care unit
up to 30 days
Length of hospital stay
Length of hospital stay
up to 30 days
Intraoperative hemodynamic complications
dysrhythmia, hypotension, hypertension, hemorrhage
during the procedure
Secondary Outcomes (6)
Oral intake
up to 30 days
pH
during the procedure
bicarbonate
during the procedure
base excess
during the procedure
lactate
during the procedure
- +1 more secondary outcomes
Study Arms (1)
Lung cancer scheduled lobectomy
Interventions
Nutritional Risk Screening-2002
Mini Nutritional Assessment
Prognostic Nutritional Index
Eligibility Criteria
18 years and older patients who underwent lobectomy with a diagnosis lung cancer
You may qualify if:
- Having a diagnosis of lung cancer
- Lung lobectomy operation will be performed
- years and older patients
- Having an American Society of Anesthesiologists score of 1, 2, 3
- Having approved and signed the informed consent form
You may not qualify if:
- Patients who underwent lobectomy with a diagnosis other than lung cancer
- Patients younger than 18 years
- Patients with an American Society of Anesthesiologists score of 4 and above
- Patients who did not accept informed consent
- Patients who refused to participate in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Bursa Uludağ Üniversitesi Tıp Fakültesi
Bursa, Nilüfer, 16000, Turkey (Türkiye)
Related Publications (6)
Cederholm T, Barazzoni R, Austin P, Ballmer P, Biolo G, Bischoff SC, Compher C, Correia I, Higashiguchi T, Holst M, Jensen GL, Malone A, Muscaritoli M, Nyulasi I, Pirlich M, Rothenberg E, Schindler K, Schneider SM, de van der Schueren MA, Sieber C, Valentini L, Yu JC, Van Gossum A, Singer P. ESPEN guidelines on definitions and terminology of clinical nutrition. Clin Nutr. 2017 Feb;36(1):49-64. doi: 10.1016/j.clnu.2016.09.004. Epub 2016 Sep 14.
PMID: 27642056BACKGROUNDMcKenna NP, Bews KA, Al-Refaie WB, Colibaseanu DT, Pemberton JH, Cima RR, Habermann EB. Assessing Malnutrition Before Major Oncologic Surgery: One Size Does Not Fit All. J Am Coll Surg. 2020 Apr;230(4):451-460. doi: 10.1016/j.jamcollsurg.2019.12.034. Epub 2020 Feb 26.
PMID: 32113029BACKGROUNDDetsky AS, McLaughlin JR, Baker JP, Johnston N, Whittaker S, Mendelson RA, Jeejeebhoy KN. What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr. 1987 Jan-Feb;11(1):8-13. doi: 10.1177/014860718701100108.
PMID: 3820522BACKGROUNDKondrup J, Rasmussen HH, Hamberg O, Stanga Z; Ad Hoc ESPEN Working Group. Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials. Clin Nutr. 2003 Jun;22(3):321-36. doi: 10.1016/s0261-5614(02)00214-5.
PMID: 12765673BACKGROUNDVellas B, Guigoz Y, Garry PJ, Nourhashemi F, Bennahum D, Lauque S, Albarede JL. The Mini Nutritional Assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition. 1999 Feb;15(2):116-22. doi: 10.1016/s0899-9007(98)00171-3.
PMID: 9990575BACKGROUNDNeelemaat F, Kruizenga HM, de Vet HC, Seidell JC, Butterman M, van Bokhorst-de van der Schueren MA. Screening malnutrition in hospital outpatients. Can the SNAQ malnutrition screening tool also be applied to this population? Clin Nutr. 2008 Jun;27(3):439-46. doi: 10.1016/j.clnu.2008.02.002. Epub 2008 Apr 18.
PMID: 18395946BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 2, 2022
First Posted
June 14, 2022
Study Start
September 29, 2021
Primary Completion
June 8, 2022
Study Completion
September 1, 2022
Last Updated
June 14, 2022
Record last verified: 2022-06