Establishment and Verification of Pancreatic Volume Formula Based on Imaging

NCT05410795 | Unknown DMC

• 1 other identifier: EPIC20220428
• Study Type: observational
• Target: 300
• Locations: 1 country
• Sites: 1

Brief Summary

This study intends to construct the linear relationship between pancreatic volume and individual attributes (height, weight, width of anterior superior iliac spine, etc.), and to establish and verify the formula of pancreatic volume.

Conditions

Healthy People; Chronic Pancreatitis; Acute Pancreatitis

Keywords

Magnetic resonance imaging; Pancreatic volume

Outcome Measures

Primary Outcomes (1)

• Pancreatic volume

  The total volume of pancreas and the volumes of head, body and tail of pancreas will be calculated by software.

  14 days after MRI examination

Study Arms (3)

Healthy people

Healthy people refer to those who exclude pancreatic related diseases, such as acute and chronic pancreatitis, pancreatic trauma, pancreatic tumor, peripancreatic lesions, diabetes and other diseases that may affect the volume of the pancreas.

Diagnostic Test: Magnetic resonance imaging

Chronic pancreatitis

Patients with chronic pancreatitis are considered as study subjects.

Diagnostic Test: Magnetic resonance imaging

Acute pancreatitis

Patients with acute pancreatitis within 144 hours after the onset of typical symptoms are considered as study subjects.

Diagnostic Test: Magnetic resonance imaging

Interventions

Magnetic resonance imaging DIAGNOSTIC_TEST

Enrolled subjects will be examined with MRI of pancreas, and the volume, length and thickness of coronal plane of pancreas will be measured by software.

Acute pancreatitis; Chronic pancreatitis; Healthy people

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Inpatients meeting the eligibility criteria.

You may qualify if:

• Healthy individuals (excluding pancreatic related diseases, such as acute and chronic pancreatitis, pancreatic trauma, pancreatic tumor, peripancreatic lesions, diabetes and other diseases that may affect the volume of the pancreas);
• Patients with chronic pancreatitis;
• Patients with acute pancreatitis within 144 hours after the onset of typical symptoms (severe persistent epigastric pain).

You may not qualify if:

• suspected to have malignant tumors;
• History of pancreas related surgery or minimally invasive treatment (such as pancreaticoduodenectomy, ERCP, etc.);
• acute exacerbation of chronic pancreatitis;
• pregnant or breastfeeding women;
• patients who refused to participate in the study.

Sponsors & Collaborators

• Changhai Hospital: lead

Study Sites (1)

Changhai Hospital

Shanghai, 200433, China

Location

MeSH Terms

Conditions

Pancreatitis, Chronic; Pancreatitis

Interventions

Magnetic Resonance Imaging

Condition Hierarchy (Ancestors)

Pancreatic Diseases; Digestive System Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Tomography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis

Study Officials

• Liang-hao Hu, MD

  Changhai Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: June 5, 2022
• First Posted: June 8, 2022
• Study Start: September 5, 2022
• Primary Completion: September 5, 2022
• Study Completion: December 1, 2022
• Last Updated: September 14, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)