Osteoarthrosis on 7.0T Magnetic Resonance Imaging
1 other identifier
observational
100
1 country
1
Brief Summary
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting osteoarthrosis. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater agreement. Diagnostic procedures such as 7T MRI may help ultimately improved diagnostic and therapies confidence to inform decision making than standard 3T MRI.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Apr 2022
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2022
CompletedFirst Submitted
Initial submission to the registry
April 19, 2022
CompletedFirst Posted
Study publicly available on registry
April 25, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
May 31, 2025
CompletedApril 25, 2022
April 1, 2022
2.2 years
April 19, 2022
April 22, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
The thickness of the cartilage of patellar on 7T MRI scan
Thickness of different part of the cartilage of patellar measured based on axial PD images
baseline
The T2 mapping value of the patellar cartilage on 7T MRI scan
T2 relaxation times of the patellar cartilage measured based on T2 mapping
baseline
The abnormal signal in the infrapatellar fat pad
The exist of abnormal signal in the infrapatellar fat pad detected based on sagittal PD images
baseline
Secondary Outcomes (2)
Signal change of the patellar chondral before and after rehabilitation
1 month after rehabilitation
Signal change of the infrapatellar fat pad before and after rehabilitation
1 month after rehabilitation
Interventions
Patients recruited will receive Magnetic resonance imaging.
Eligibility Criteria
patients with clinical diagnosis of patellar chondromalacia were continuously included.
You may qualify if:
- Age≥18 and ≤80
- Having no contraindications against MRI
- Clinically stable
You may not qualify if:
- Age#18 or #80
- Pregnancy and other contraindication to MRI scan
- Informed consent not obtained
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Chinese PLA General Hospital
Beijing, 100853, China
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Director and Clinical Professor
Study Record Dates
First Submitted
April 19, 2022
First Posted
April 25, 2022
Study Start
April 1, 2022
Primary Completion
May 31, 2024
Study Completion
May 31, 2025
Last Updated
April 25, 2022
Record last verified: 2022-04