Prevalence of May-Thurner Syndrome in 1st-degree Relatives of Symptomatic Patients

NCT05409781 | Withdrawn

• 1 other identifier: DVS002
• Study Type: observational
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim is to assess the prevalence of May-Thurner syndrome in 1st-degree relatives of previously identified symptomatic patients.

Conditions

May-Thurner Syndrome

Outcome Measures

Primary Outcomes (1)

• Prevalence Assessment

  To assess the prevalence of May-Thurner syndrome amongst 1st-degree relatives of symptomatic individuals referred to the Vascular Department, University Hospital Limerick using duplex ultrasound imaging

  1 year

Secondary Outcomes (1)

• Venous Competence Assessment

  1 year

Interventions

No Intervention OTHER

No Intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

The pathogenesis of MTS is largely unknown and whilst the condition is known to be more prevalent in females, familial risk factors are largely unknown. To our knowledge, no studies have previously assessed the prevalence of MTS in relatives of those with the condition.

You may qualify if:

• Informed consent, first degree relative with symptomatic May-Thurner syndrome

You may not qualify if:

• Those who not give informed consent to be contacted or to be scanned.

Sponsors & Collaborators

• University Hospital of Limerick: lead

MeSH Terms

Conditions

May-Thurner Syndrome

Condition Hierarchy (Ancestors)

Vascular Malformations; Cardiovascular Abnormalities; Cardiovascular Diseases; Peripheral Vascular Diseases; Vascular Diseases; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Nurse Manager

Study Record Dates

• First Submitted: June 3, 2022
• First Posted: June 8, 2022
• Study Start: September 15, 2025
• Primary Completion: December 15, 2025
• Study Completion: January 15, 2026
• Last Updated: September 18, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share