NCT05395650

Brief Summary

is cyanocobalamin active as Photosensitizing Agent instead of riboflavin ? using cyanocobalamin with mix of external collagen to make crosslinking with cornea collagen to make rigid of cornea

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2023

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 25, 2022

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 27, 2022

Completed
1.3 years until next milestone

Study Start

First participant enrolled

September 1, 2023

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2023

Completed
Last Updated

February 15, 2023

Status Verified

February 1, 2023

Enrollment Period

1 month

First QC Date

May 25, 2022

Last Update Submit

February 14, 2023

Conditions

Keratoconus

Outcome Measures

Primary Outcomes (1)

  • PRESERVATION of presence of red flare by using slit lamb

    Cyanocobalamin react with cornea collagen and format red flare

    Base line

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

primary care

You may qualify if:

  • \- Is 20 years or older Has been diagnosed with Keratoconus; Has no other active ocular disease; Is not pregnant or nursing;

You may not qualify if:

  • Is under the age of 20 Has best corrected visual acuity outside 20/400; Pregnant or nursing at the time of enrollment in the study;

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Keratoconus

Condition Hierarchy (Ancestors)

Corneal DiseasesEye Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
R&D Manger

Study Record Dates

First Submitted

May 25, 2022

First Posted

May 27, 2022

Study Start

September 1, 2023

Primary Completion

October 1, 2023

Study Completion

December 1, 2023

Last Updated

February 15, 2023

Record last verified: 2023-02