Dental and Periodontal Changes Following the Acceleration of Alignment of Crowded Lower Anterior Teeth Using a Surgical Technique

NCT05390320 | Completed DMC

• 1 other identifier: UDDS-Ortho-10-2022
• Study Type: interventional
• Target: 38
• Locations: 1 country
• Sites: 1

Brief Summary

Patients at the Orthodontic Department of the University of Damascus Dental School will be examined and subjects who meet the inclusion criteria will be included. Then, initial diagnostic records (diagnostic gypsum models, internal and external oral photographs, and radiographic images) will be studied to ensure that the selection criteria are accurately matched. This study aims to compare two groups of patients with moderate crowding of the lower anterior teeth. Experimental group: the patients in this group will be treated with periodontally accelerated osteogenic orthodontics Control group: the patients in this group will be treated using fixed appliances without any acceleration method.

Conditions

Crowding, Tooth

Keywords

PAOO; moderate crowding; gingival index; plaque index; papillary bleeding index

Outcome Measures

Primary Outcomes (3)

• Change in Little's Index of Irregularity

  The irregularity of the lower incisors is calculated by measuring the amount of deviations of the anatomic contact points between the six anterior teeth in the horizontal direction in mm, since the sum of these measurements represents the value of the index (Little, 1975). The ordinary orthodontic treatment aims to keep this Index less than 1 mm at the end of treatment.

  T0: one day before the beginning of treatment; T1: after 1 month; T2: after 2 months; T3: after 4 months; T4: after 5 months; T5: at the end of the alignment stage which is expected within 5 - 6 months

• Change in the inter-canine width

  The distance between the cusp tips of the lower canines. This variable will be measured on plaster models.

  T0: One day before the beginning of treatment; T1: at the end of the alignment stage

• Change in the inter-2nd premolar width

  The distance between the central fossae of the lower second premolars. This variable will be measured on plaster models.

  T0: One day before the beginning of treatment; T1: at the end of the alignment stage

Secondary Outcomes (3)

• Change in the Gingival index

  T0: One day before the beginning of treatment; T1: at the end of the alignment stage

• Change in the Plaque index

  T0: One day before the beginning of treatment; T1: at the end of the alignment stage

• Change in the Papillary Bleeding Index

  T0: One day before the beginning of treatment; T1: at the end of the alignment stage

Study Arms (2)

Periodontally accelerated osteogenic orthodontics

EXPERIMENTAL

The patients in this group will be treated by periodontally accelerated osteogenic orthodontics using fixed appliances.

Procedure: PAOO

Conventional treatment

ACTIVE COMPARATOR

The patients in this group will be treated using fixed appliances and conventional treatment without any surgical intervention to accelerate tooth movement.

Other: Fixed appliance

Interventions

PAOO PROCEDURE

Periodontally accelerated osteogenic orthodontics will be applied to treat patients with moderate crowding.

Periodontally accelerated osteogenic orthodontics

Fixed appliance OTHER

Fixed appliances will be applied to treat patients with moderate crowding without any acceleration methods.

Conventional treatment

Eligibility Criteria

• Age: 18 Years - 28 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• skeletal class I malocclusion (ANB=2-4)
• normal vertical growth pattern.
• moderate crowding of lower anterior teeth (i.e., 4-6 millimeters of a tooth size-arch length discrepancy)
• to 3 mm of overjet and 1 to 4 mm of the overbite
• good oral health

You may not qualify if:

• medical, social, and psycho contraindications to oral surgery
• presence of periodontal diseases
• poor oral hygiene
• previous orthodontic treatment

Sponsors & Collaborators

• Damascus University: lead

Study Sites (1)

University of Damascus

Damascus, Syria

Location

Related Publications (5)

• Yu H, Jiao F, Wang B, Shen SG. Piezoelectric decortication applied in periodontally accelerated osteogenic orthodontics. J Craniofac Surg. 2013;24(5):1750-2. doi: 10.1097/SCS.0b013e3182902c5a.

  PMID: 24036771 BACKGROUND

• Wu J, Jiang JH, Xu L, Liang C, Bai Y, Zou W. A pilot clinical study of Class III surgical patients facilitated by improved accelerated osteogenic orthodontic treatments. Angle Orthod. 2015 Jul;85(4):616-24. doi: 10.2319/032414-220.1. Epub 2014 Oct 27.

  PMID: 25347045 BACKGROUND

• Bahammam MA. Effectiveness of bovine-derived xenograft versus bioactive glass with periodontally accelerated osteogenic orthodontics in adults: a randomized, controlled clinical trial. BMC Oral Health. 2016 Nov 30;16(1):126. doi: 10.1186/s12903-016-0321-x.

  PMID: 27903250 BACKGROUND

• Amit G, Jps K, Pankaj B, Suchinder S, Parul B. Periodontally accelerated osteogenic orthodontics (PAOO) - a review. J Clin Exp Dent. 2012 Dec 1;4(5):e292-6. doi: 10.4317/jced.50822. eCollection 2012 Dec 1.

  PMID: 24455038 BACKGROUND

• Nowzari H, Yorita FK, Chang HC. Periodontally accelerated osteogenic orthodontics combined with autogenous bone grafting. Compend Contin Educ Dent. 2008 May;29(4):200-6; quiz 207, 218.

  PMID: 18533317 BACKGROUND

MeSH Terms

Conditions

Malocclusion

Interventions

Orthodontic Appliances, Fixed

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Orthodontic Appliances; Orthodontics; Dentistry

Study Officials

• Hallaj I Alsino, DDS

  Department of orthodontics, Damascus University, Syria

  PRINCIPAL INVESTIGATOR

• Mohammad Y Hajeer, DDS,MSc,PhD

  Department of orthodontics, Damascus University, Syria

  STUDY DIRECTOR

• Issam Khoury, DDS,MSc,PhD

  Department of Oral and Maxillofacial Surgery, Damascus University, Syria

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 20, 2022
• First Posted: May 25, 2022
• Study Start: January 1, 2021
• Primary Completion: October 6, 2021
• Study Completion: February 1, 2022
• Last Updated: May 25, 2022

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will not share

Locations

SY (1)