Analysis of Gingival Crevicular Fluid Levels of miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p in CVD and Periodontitis
Sponsor study identifier
observational
115
1 country
1
Study Start
April 1, 2019
Actual (reported)Primary Completion
October 30, 2021
Actual (reported)Study Completion
December 15, 2021
Actual (reported)Several micro-RNA plays a key role in endothelial function and may be a link for the known interaction of periodontitis and cardiovascular disease. The investigators compared the impact of gingival health, periodontitis (CP), cardiovascular disease or of both diseases (CP +cardiovascular disease) on gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 15, 2021
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 1, 2019
Actual (reported)October 30, 2021
Actual (reported)December 15, 2021
Actual (reported)May 16, 2022
Actual (reported)May 20, 2022
Actual (reported)Clinical Attachment level
Evaluation of changes (in millimeters) of Clinical attachment level loss
1-year
Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Evaluation of gingival crevicular fluid miRNA 7a-5p, miRNA 21-3p, miRNA 21-5p, miRNA 200b-3p, miRNA 200b-5p, miRNA 100-5p, miRNA 125-5p levels.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
healthy controls (n=28), periodontitis (n=30), CVD (n=28), and a combination of periodontitis + CVD (n=29)
University of Catania
Catania, CT, 95124, Italy
Gaetano Isola
Università degli Studi di Catania
115 participants (actual enrollment reported by the registry).
First Submitted
May 16, 2022
First Posted
May 20, 2022
Study Start
April 1, 2019
Actual (reported)Association of Asprosin in Periodontitis and Acute Coronary Syndrome
Contact the study team to confirm eligibility.
Primary Completion
October 30, 2021
Actual (reported)Study Completion
December 15, 2021
Actual (reported)Last Updated
May 20, 2022
Record last verified: 2022-05
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Source: ClinicalTrials.gov.
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