Risk Factor for Readmission and Death of Lower Respiratory Infections in Older Adults

NCT05355324 | Completed

• 1 other identifier: YuHe_1987
• Study Type: observational
• Target: 215
• Locations: 0 countries
• Sites: N/A

Brief Summary

Lower respiratory tract infection(LRTI) is a prevalent disease that threatens the health of older people worldwide. Anemia is also a common disorder in the elderly, and its prevalence increases significantly with age. Most factors that contribute to the development of anemia are improvable. Therefore, we investigated whether anemia was a risk factor for LRTI-caused readmission and death in the elderly occurring within 1 year of discharge from the hospital.

Conditions

Lower Respiratory Infection; Anemia; Readmission; Death

Outcome Measures

Primary Outcomes (1)

• Number of Patients with Readmission and/ or Death Caused by Lower Respiratory Tract Infection(LRTI) within One Year of Discharge

  Number of Patients with Readmission Caused by LRTI within One Year of Discharge. Number of Patients with Death Caused by LRTI within One Year of Discharge.

  March 2016 to 27 December 2019

Study Arms (2)

anemia

patients with anemia

Other: no intervention

non-anemia

patients without anemia

Other: no intervention

Interventions

no intervention OTHER

no intervention

anemia; non-anemia

Eligibility Criteria

• Age: 80 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Elderly patients (age: ≥ 80 years), hospitalized (from 31 March 2016 to 27 December 2019) at the Department of Geriatrics of a hospital in Beijing, China, and were with lower respiratory tract infection(LRTI) (including pneumonia and acute exacerbation of chronic obstructive pulmonary disease) were included. 215 patients (age: \>/=80 years) who were hospitalized due to LRTI and discharged after being cured were studied. Of these 215 patients, 149 belonged to the anemia group, and 66 belonged to the non-anemia group. The mean age of the cohort at the time of inclusion was 88.73 (SD 4.765) years, and 77.2% of the patients were men.

You may qualify if:

• Age ≥ 80 years
• lower respiratory tract infection

You may not qualify if:

• Died at the time of first admission
• Active malignancy
• Tuberculosis
• Anemia caused by gastrointestinal bleeding of unknown origin
• Achalasia of the cardia
• Could not be followed up after discharge
• Data were missing

Sponsors & Collaborators

• Beijing Tongren Hospital: lead

Related Publications (1)

• He Y, Chen Y, Cao K, Zheng H. Effect of Anemia on Readmission and Death in Octogenarian Patients with Lower Respiratory Tract Infections: A Retrospective Cohort Study. Int J Clin Pract. 2022 Oct 27;2022:4566936. doi: 10.1155/2022/4566936. eCollection 2022.

  PMID: 36349057 DERIVED

MeSH Terms

Conditions

Anemia; Death

Condition Hierarchy (Ancestors)

Hematologic Diseases; Hemic and Lymphatic Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 21, 2022
• First Posted: May 2, 2022
• Study Start: March 1, 2016
• Primary Completion: December 31, 2019
• Study Completion: December 31, 2021
• Last Updated: May 2, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share