NCT05341076

Brief Summary

The current study aims at evaluating the impact of the implementation of the labor scale, in comparison to the standard WHO partograph, in the management of primiparous women, including CD rate, maternal and neonatal outcomes of labor.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
206

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2022

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 11, 2022

Completed
11 days until next milestone

First Posted

Study publicly available on registry

April 22, 2022

Completed
3 months until next milestone

Study Start

First participant enrolled

August 1, 2022

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2023

Completed
Last Updated

April 22, 2022

Status Verified

April 1, 2022

Enrollment Period

11 months

First QC Date

April 11, 2022

Last Update Submit

April 16, 2022

Conditions

Keywords

Labor scalePartographSpontaneous laborPrimigravida

Outcome Measures

Primary Outcomes (1)

  • Successful vaginal delivery (reporting of whether labor ends in vaginal delivery or Cesarean Section. In case of CS, the indication will be reported)

    The proportion who delivered vaginal versus those indicated for Cesarean Section for labor dystocia

    Duration of labor (maximum 24 hours from onset of labor)

Secondary Outcomes (9)

  • Intrapartum maternal birth injuries

    Duration of labour and hospital stay (anticipated duration: 72 hours)

  • Primary postpartum hemorrhage

    Within 24 hours of delivery

  • Maternal fever/postpartum infections

    Within 24 hours of delivery

  • Intrapartum fetal distress

    Duration of labor (maximum 24 hours)

  • Birth injuries of the newborn

    The length of neonatal hospital stay (anticipated duration: 72 hours)

  • +4 more secondary outcomes

Study Arms (2)

Labor scale

EXPERIMENTAL

Observation Amniotomy Oxytocin Cesarean Section (CS)

Procedure: AmniotomyDrug: OxytocinProcedure: Cesarean Section

WHO partograph

ACTIVE COMPARATOR

Observation Amniotomy Oxytocin Cesarean Section (CS)

Procedure: AmniotomyDrug: OxytocinProcedure: Cesarean Section

Interventions

AmniotomyPROCEDURE

Amniotomy, artificial rupture of membranes, is done with an initial delay of labor (in partograph: extension beyond the alert line, in labor scale: when progress reaches the membrane line)

Also known as: Artificial rupture of membranes
Labor scaleWHO partograph

oxytocin augmentation: given with further delay of labor (according to the point of intervention of the partograph or the scale)

Also known as: augmentation of labor
Labor scaleWHO partograph

Cesarean section: done when progress is deemed arrested (according to the definition of the partograph or the scale)

Also known as: CS
Labor scaleWHO partograph

Eligibility Criteria

Age18 Years - 45 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility DetailsN/A (study targets pregnant women in labor)
Healthy VolunteersNo
Age GroupsAdult (18-64)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Aswan Faculty of Medicine

Aswān, 81528, Egypt

Location

Related Publications (8)

  • American College of Obstetricians and Gynecologists (College); Society for Maternal-Fetal Medicine; Caughey AB, Cahill AG, Guise JM, Rouse DJ. Safe prevention of the primary cesarean delivery. Am J Obstet Gynecol. 2014 Mar;210(3):179-93. doi: 10.1016/j.ajog.2014.01.026.

    PMID: 24565430BACKGROUND
  • Hamilton BE, Hoyert DL, Martin JA, Strobino DM, Guyer B. Annual summary of vital statistics: 2010-2011. Pediatrics. 2013 Mar;131(3):548-58. doi: 10.1542/peds.2012-3769. Epub 2013 Feb 11.

    PMID: 23400611BACKGROUND
  • Gregory KD, Jackson S, Korst L, Fridman M. Cesarean versus vaginal delivery: whose risks? Whose benefits? Am J Perinatol. 2012 Jan;29(1):7-18. doi: 10.1055/s-0031-1285829. Epub 2011 Aug 10.

    PMID: 21833896BACKGROUND
  • Neal JL, Ryan SL, Lowe NK, Schorn MN, Buxton M, Holley SL, Wilson-Liverman AM. Labor Dystocia: Uses of Related Nomenclature. J Midwifery Womens Health. 2015 Sep-Oct;60(5):485-98. doi: 10.1111/jmwh.12355.

    PMID: 26461188BACKGROUND
  • HealthyPeople.gov. Search the Data | Healthy People 2020 [Internet]. 2017 [cited 2022 Mar 28]. p. 1-6. Available from: https://www.healthypeople.gov/2020/data-search/Search-the-Data#objid=4660;

    BACKGROUND
  • Tolba SM, Ali SS, Mohammed AM, Michael AK, Abbas AM, Nassr AA, Shazly SA. Management of Spontaneous Labor in Primigravidae: Labor Scale versus WHO Partograph (SLiP Trial) Randomized Controlled Trial. Am J Perinatol. 2018 Jan;35(1):48-54. doi: 10.1055/s-0037-1605575. Epub 2017 Aug 8.

    PMID: 28787749BACKGROUND
  • Shazly SA, Embaby LH, Ali SS. The labour scale--assessment of the validity of a novel labour chart: a pilot study. Aust N Z J Obstet Gynaecol. 2014 Aug;54(4):322-6. doi: 10.1111/ajo.12209. Epub 2014 May 17.

    PMID: 24835694BACKGROUND
  • Lavender T, Cuthbert A, Smyth RM. Effect of partograph use on outcomes for women in spontaneous labour at term and their babies. Cochrane Database Syst Rev. 2018 Aug 6;8(8):CD005461. doi: 10.1002/14651858.CD005461.pub5.

    PMID: 30080256BACKGROUND

MeSH Terms

Conditions

Dystocia

Interventions

AmniotomyOxytocinCesarean Section

Condition Hierarchy (Ancestors)

Obstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Intervention Hierarchy (Ancestors)

Labor, InducedDelivery, ObstetricObstetric Surgical ProceduresSurgical Procedures, OperativePituitary Hormones, PosteriorPituitary HormonesPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPeptidesAmino Acids, Peptides, and Proteins

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.B.B.Ch, M.S.c

Study Record Dates

First Submitted

April 11, 2022

First Posted

April 22, 2022

Study Start

August 1, 2022

Primary Completion

July 1, 2023

Study Completion

September 1, 2023

Last Updated

April 22, 2022

Record last verified: 2022-04

Data Sharing

IPD Sharing
Will not share

Locations