NCT02941393

Brief Summary

In this study, parturients will be randomized to either internal or external tocodynamometry contractions' follow up. Investigators recruit primiparous, those who try to have vaginal birth after cesarean section and multiparous, who need oxytocin during labor. Primary endpoint is the number of operative labors in each group. Secondary endpoints are the duration of labor, the use of oxytocin and the condition of the newborn.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2012

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2012

Completed
3.9 years until next milestone

First Submitted

Initial submission to the registry

September 7, 2016

Completed
1 month until next milestone

First Posted

Study publicly available on registry

October 21, 2016

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
Last Updated

March 20, 2018

Status Verified

March 1, 2018

Enrollment Period

5.2 years

First QC Date

September 7, 2016

Last Update Submit

March 19, 2018

Conditions

Keywords

internal tocodynamometry, external tocodynamometry, cesarean section, labor, newborn, vacuum extraction, dystocia

Outcome Measures

Primary Outcomes (2)

  • Number of cesarean sections

    through study completion, an average of 6 years

  • Number of operative vaginal deliveries

    through study completion, an average of 6 years

Secondary Outcomes (5)

  • Duration of labor

    From time of first regular contraction to birth

  • Newborn admission to the pediatric care unit

    3 days after birth

  • The use of Oxytocin during labor

    From beginning of the use of oxytocin to the birth

  • Apgar scores

    10 min after birth

  • Ph of umbilical artery

    immediately after birth

Study Arms (2)

Intrauterine pressure catheter

ACTIVE COMPARATOR

Intrauterine pressure catheter is used during labor to follow up the contractions

Device: Intrauterine pressure catheter

External tocodynamometry

ACTIVE COMPARATOR

External tocodynamometry is used during labor to follow up the contractions

Device: External tocodynamometry

Interventions

Also known as: Internal tocodynamometry
Intrauterine pressure catheter
External tocodynamometry

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • gestational age ≥ 37 weeks
  • singleton pregnancy
  • a fetus in cephalic position
  • normal cardiotocograph in the time of randomization
  • cervical ripening \< 7 cm
  • either 1) primipara, 2) multipara, who needs oxytocin during first stage of labor or 3) parturients with previous cesarean section

You may not qualify if:

  • parturient with hepatitis or HIV or other significant viral infection
  • Acute infections (fever over 37,5, or C-reactive protein over 20) in the time of randomization
  • Estimated fetal weight over 4,5 kg
  • Suspected fetal abnormality

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Cetral Finland Central Hospital

Jyväskylä, Central Finland, 40640, Finland

Location

Tampere University Hospital

Tampere, Pirkanmaa, 33520, Finland

Location

MeSH Terms

Conditions

Dystocia

Condition Hierarchy (Ancestors)

Obstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Study Officials

  • Tuija Hautakangas, MD

    Central Finland Central Hospital, Tampere University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical doctor

Study Record Dates

First Submitted

September 7, 2016

First Posted

October 21, 2016

Study Start

November 1, 2012

Primary Completion

December 31, 2017

Study Completion

December 31, 2017

Last Updated

March 20, 2018

Record last verified: 2018-03

Data Sharing

IPD Sharing
Will not share

Locations