Bilateral Uterine Artery Ligation in Reducing Incidence of Postpartum Hemorrhage in Cesarean Section
Role of Bilateral Uterine Artery Ligation in Reducing Incidence of Postpartum Hemorrhage in Cesarean Section in Patients At Risk of Uterine Atony A Randomized Controlled Trial
1 other identifier
interventional
1,070
1 country
1
Brief Summary
The patients were recruited from women attending labor ward to undergo cesarean section.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Dec 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2017
CompletedFirst Submitted
Initial submission to the registry
July 8, 2018
CompletedFirst Posted
Study publicly available on registry
July 19, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 30, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2019
CompletedMarch 11, 2019
March 1, 2019
12 months
July 8, 2018
March 8, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
mean Blood loss after placental separation
by using weight of soaked towels (weight of soaked towel - weight of dry towel) and amount of blood in suction set
30 minutes
Study Arms (2)
study group
EXPERIMENTALpatients at risk of uterine atony undergoing cesarean section underwent bilateral uterine artery ligation and received oxytocin.
control group
ACTIVE COMPARATORpatients at risk of uterine atony undergoing cesarean section received oxytocin only.
Interventions
• The peritoneum over the vesico-uterine pouch already being incised horizontally, the peritoneum over the uterine isthmus and cervix was dissected downwards, and this dissection was then extended laterally.
Eligibility Criteria
You may qualify if:
- Women with one or more of the following conditions undergoing cesarean section for obstetric indication were included:
- Maternal anemia (not less than 7 gm %).
- Macrosomic baby \>4kgs.
- Twin pregnancy and high order pregnancy.
- Polyhydramnios.
- Grand multipara.
- Previous history of atonic postpartum hemorrhage.
- Prolonged vaginal delivery.
- Emergency cesarean.
- Chorioamnionitis.
You may not qualify if:
- \- Placenta previa.
- Patients with bleeding tendency (congenital or acquired)
- Ante-partum hemorrhage.
- Patients with no risk for uterine atony.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ahmed Abbas
Assiut, Cairo Governorate, 002, Egypt
Related Publications (1)
Samy A, Ali MK, Abbas AM, Wahab HA, Wali AA, Hussien AH, Mostafa M, Taymour MA, Ogila AI, Ahmad Y, Essam A, Mahmoud M. Randomized controlled trial of the effect of bilateral uterine artery ligation during cesarean among women at risk of uterine atony. Int J Gynaecol Obstet. 2020 Feb;148(2):219-224. doi: 10.1002/ijgo.13064. Epub 2019 Dec 10.
PMID: 31755559DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
July 8, 2018
First Posted
July 19, 2018
Study Start
December 1, 2017
Primary Completion
November 30, 2018
Study Completion
January 1, 2019
Last Updated
March 11, 2019
Record last verified: 2019-03