Outcomes After Perioperative Stroke Following Cardiac Surgery

NCT05333146 | Unknown

• 1 other identifier: H21-03915
• Study Type: observational
• Target: 906
• Locations: 1 country
• Sites: 1

Brief Summary

Perioperative stroke is a devastating complication of cardiac surgery that is currently poorly characterized but occurs in 1-5% of patients and is associated with poor outcomes including increased mortality. Given the uncommon nature of this complication, relatively little is known about which factors predict these outcomes among those who experience a perioperative stroke. The study objectives are to identify predictors of mortality, length of stay and discharge disposition after perioperative stroke in cardiac surgery using the prospectively-collected American College of Surgeons National Surgical Quality Improvement Program database between 2005 and 2020.

Conditions

Perioperative Complication; Stroke, Acute; Stroke, Complication; Stroke, Cardiovascular; Cardiovascular Diseases

Outcome Measures

Primary Outcomes (1)

• Death

  Death

  Within 30 days of surgery

Secondary Outcomes (2)

• Adverse discharge

  Within 30 days of surgery

• Length of stay

  Within 30 days of surgery

Other Outcomes (1)

• Intensive care utilization

  Within 30 days of surgery

Interventions

Cardiac Surgery PROCEDURE

Cardiac surgery (e.g. coronary bypass surgery, cardiac valve surgery, ascending aortic surgery)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients who received a diagnosis of stroke in the NSQIP database after a cardiac surgical procedure between 2005 and 2020.

You may qualify if:

• Experienced a perioperative stroke
• Underwent cardiac surgery

You may not qualify if:

• \- none

Sponsors & Collaborators

• University of British Columbia: lead

Study Sites (1)

University of British Columbia

Vancouver, British Columbia, Canada

RECRUITING

MeSH Terms

Conditions

Stroke; Myocardial Infarction; Cardiovascular Diseases

Interventions

Cardiac Surgical Procedures

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Myocardial Ischemia; Heart Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Intervention Hierarchy (Ancestors)

Cardiovascular Surgical Procedures; Surgical Procedures, Operative; Thoracic Surgical Procedures

Study Officials

• Alana Flexman, MD

  University of British Columbia

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Alana Flexman, MD

CONTACT

(604) 806-8337; aflexman@providencehealth.bc.ca

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: April 11, 2022
• First Posted: April 18, 2022
• Study Start: April 18, 2022
• Primary Completion: October 31, 2022
• Study Completion: July 1, 2023
• Last Updated: June 30, 2022

Record last verified: 2022-06

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)