Virtual Reliability System for Visual Spatial Attention Evaluation in Stroke Patients

NCT05332964 | Completed

• 1 other identifier: 202104030RINC
• Study Type: observational
• Target: 1
• Locations: 1 country
• Sites: 1

Brief Summary

The researchers designed a software based on a head-mounted displays for virtual reality (HMD-VR) to evaluate the reaction time to stimuli presented at right or left visual field. The study will recruit 100 stroke patients with hemisphere lesions (50 patients for right and left each) and 100 age-matched healthy controls. The participants will conduct a simple reaction time task in VR, with stimuli designated in the left or right hemi-field. The stroke patients will also received traditional tests for hemi-neglect. Test-retest reliability of the assessment will be conducted in a subset of the control group. The stroke patients will be followed in 3-4 weeks.

Conditions

Stroke Sequelae; Neglect, Hemispatial

Keywords

attention; hemineglect; virtual reality; reaction time

Outcome Measures

Primary Outcomes (2)

• reaction time

  reaction time to the stimuli presented in the right or left hemi-field with VR software

  4 weeks

• hemineglect tests

  Paper-based behavior inattention test (BIT)

  4 weeks

Secondary Outcomes (3)

• ADL

  4 weeks

• cognition

  4 weeks

• cybersickness

  1 day

Study Arms (3)

stroke (right)

stroke patient with lesions at right hemisphere

stroke (left)

stroke patient with lesions at left hemisphere

control

age-matched group for the stroke patients

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

outpatient and inpatient rehabilitation unit in a medical center

You may qualify if:

• aged at least 20 years old
• diagnosed with stroke involving unilateral MCA and ACA territory
• with unilateral upper limb with normal function
• neurologically and medically stable.
• \) healthy adults, age-matched to stroke patients

You may not qualify if:

• with history of neurological or psychiatric conditions other than stroke;
• significant cognitive or speech problems that cause difficulties to cooperate with testing;
• significant visual problems (such as color blindness, visual loss, cataract, glaucoma or other major eye condition)
• upper limb musculoskeletal disorders to cause difficulties to use the keyboard or controller;
• history of seizure, vestibular dysfunction or vertigo
• can't tolerate HMD-VR

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

Location

MeSH Terms

Conditions

Perceptual Disorders

Condition Hierarchy (Ancestors)

Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Huey-Wen Liang, MD

  National Taiwan University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 11, 2022
• First Posted: April 18, 2022
• Study Start: March 1, 2025
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: February 24, 2026

Record last verified: 2025-02

Locations

TW (1)