Use of ΔIVC for Early Diagnosis of AHF in AECOPD

NCT05327374 | Completed

• 1 other identifier: ΔIVC /AHF/ AECOPD
• Study Type: observational
• Target: 401
• Locations: 1 country
• Sites: 3

Brief Summary

Acute Heart failure (AHF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis. The investigators expect that the application of the inferior vena cava collapsibility index (ΔIVC)could be useful in this issue.

Conditions

Acute Decompensated Heart Failure; COPD Exacerbation

Keywords

COPD; Acute Heart Failure; Inferior vena cava; Ultrasound; Collapsibility index

Outcome Measures

Primary Outcomes (1)

• the performance of ΔIVC in the diagnosis of acute heart failure

  the accuracy of ΔIVC in the diagnosis of heart failure measured by sensitivity ,specificity, and area under the roc curve

  1 day

Study Arms (2)

AHF-group

patients with AECOPD and acute heart failure

Diagnostic Test: calculation of the inferior vena cava collapsibility index

non AHF-group

patients with AECOPD without acute heart failure

Diagnostic Test: calculation of the inferior vena cava collapsibility index

Interventions

calculation of the inferior vena cava collapsibility index DIAGNOSTIC_TEST

the ΔIVC was calculated by the emergency physician who was blinded from the patient's medical history using the formula ((IVCmax-IVCmin)/IVCmax) X100.A cutoff of 15% was used to define the presence(\<15%) or absence(\>15%) of heart failure

AHF-group; non AHF-group

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients with history of COPD admitted to the emergency departmet for AECOPD and stable hemodynamic status

You may qualify if:

• patient with history of COPD and admitted to the emergency departement for AECOPD

You may not qualify if:

• impossibility to give consent to participate in the study, non consent patients
• post traumatic dyspnea
• instable hemodynamic or neurological status

Sponsors & Collaborators

• University of Monastir: lead

Study Sites (3)

CHU Fattouma Bourguiba

Monastir, 5000, Tunisia

Location

Emergency Departement

Monastir, 5000, Tunisia

Location

Emergency department of fattouma bourguiba university hospital

Monastir, 5020, Tunisia

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Nouira Semir, Professor

  University of Monastir

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: professor

Study Record Dates

• First Submitted: March 14, 2022
• First Posted: April 14, 2022
• Study Start: March 1, 2022
• Primary Completion: November 30, 2022
• Study Completion: January 31, 2023
• Last Updated: May 16, 2023

Record last verified: 2023-05

Locations

TU (3)