NCT05308069

Brief Summary

This study will evaluate changes in visual performance at different pupil sizes between a single vision soft contact lens and multifocal soft contact lens, and compare refractive error measured between these two lenses with an autorefractor and an aberrometer

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 24, 2022

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 1, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

June 13, 2022

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 27, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 27, 2022

Completed
Last Updated

August 9, 2022

Status Verified

August 1, 2022

Enrollment Period

1 month

First QC Date

March 24, 2022

Last Update Submit

August 6, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Visual performance

    Low contrast visual performance will be measured at different pupil sizes for each subject while wearing each of the two lenses

    Through completion of study visit, an average of 3 hours

Secondary Outcomes (1)

  • Refractive error

    Through completion of study visit, an average of 3 hours

Study Arms (2)

Single vision contact lens

OTHER

Subjects will wear a single vision soft contact lens during the study visit

Device: Single vision contact lens

Multifocal contact lens

OTHER

Subjects will wear a multifocal soft contact lens during the study visit

Device: Multifocal contact lens

Interventions

Subjects will wear a single vision soft contact lens only during the study visit

Also known as: comfilcon A
Single vision contact lens

Subjects will wear a multifocal soft contact lens only during the study visit

Also known as: comfilcon A
Multifocal contact lens

Eligibility Criteria

Age18 Years - 39 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Able to read and understand the informed consent document
  • to 39 years of age (inclusive)
  • Best corrected visual acuity of 20/25 or better in the right eye
  • Refractive error from -1.00D to -8.00D with astigmatism less than or equal to -1.00D in the right eye (corneal plane)

You may not qualify if:

  • Any ocular or systemic conditions affecting vision, refraction, or the ability to wear a soft contact lens
  • History of ocular trauma or surgery causing abnormal or distorted vision
  • Current Rigid Gas Permeable (RGP) contact lens wearers
  • Pregnant and/or lactating females, by self-report

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Houston

Houston, Texas, 77204, United States

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Officials

  • David A Berntsen, OD, PhD

    University of Houston College of Optometry

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

March 24, 2022

First Posted

April 1, 2022

Study Start

June 13, 2022

Primary Completion

July 27, 2022

Study Completion

July 27, 2022

Last Updated

August 9, 2022

Record last verified: 2022-08

Data Sharing

IPD Sharing
Will not share

Locations