NCT05307484

Brief Summary

Dengue can be mitigated by both vector control and vaccination. Serious games in healthcare can be used to raise the community awareness of vector control in dengue prevention in a simulated interactive learning environment, by motivating serious game participants to optimise their own performance and influence their behaviour. The results show a specially designed serious game can better engage local residents by raising their awareness in vector control and proactiveness in dengue prevention. At least 8 out of 10 participants were willing to be vaccinated against dengue if they knew of the availability of a safe and effective vaccine.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 3, 2021

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 17, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 17, 2021

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

March 18, 2022

Completed
14 days until next milestone

First Posted

Study publicly available on registry

April 1, 2022

Completed
Last Updated

April 1, 2022

Status Verified

March 1, 2022

Enrollment Period

7 months

First QC Date

March 18, 2022

Last Update Submit

March 29, 2022

Conditions

Keywords

Serious gameDengue preventionPrimary care

Outcome Measures

Primary Outcomes (1)

  • Change of knowledge, attitude and practice (KAP) assessment score on dengue fever prevention

    This outcome is measured via a participant-administered questionnaire which was used and validated in previous regional studies. It is divided into 3 sections: (1) knowledge (16 items), (2) attitude (15 items), (3) practice (15 items) in preventing dengue. The minimum and maximum values of this questionnaire are 0 and 46 respectively. A higher score indicates a better outcome.

    Change from baseline KAP score at 2 weeks (or within 2 weeks after completion of intervention)

Secondary Outcomes (2)

  • Change of interest to vaccinate against Dengue

    Change from baseline Dengue vaccination interest at 2 weeks (or within 2 weeks after completion of intervention)

  • System Usability Scale (SUS) score of serious game

    At 2 weeks from start of study (or within 2 weeks after completion of intervention by the serious game group)

Study Arms (2)

Serious game group

EXPERIMENTAL

Participants in the intervention group installed a mobile application, 'Sam's Mozzie Adventure'. This is a locally designed serious game which was co-created between SingHealth Polyclinics and AI Innovation Labs (AI2 Labs) Private Limited, specifically for this study. The principal investigator reviewed existing publicly available information on dengue prevention, including those on the National Environmental Agency (NEA) 'Stop Dengue' website, and provided the relevant content and pedagogical knowledge to the team of app developers from AI2 Labs. After creating the syllabus, the developers deployed their technological knowledge to integrate the dengue prevention information into the serious game. The participants were instructed to complete playing this serious game within 2 weeks.

Other: Serious game

Dengue prevention website group

ACTIVE COMPARATOR

The control group accessed the NEA 'Stop Dengue' website which contained dengue prevention information in the forms of online articles, posters and video. The participants were instructed to complete reading the online resources within 2 weeks.

Other: Dengue prevention website

Interventions

This is a serious game in the form of a mobile application, designed to educate adults on dengue prevention.

Also known as: Sam's Mozzie Adventure
Serious game group

This is a website containing information regarding dengue prevention.

Also known as: National Environmental Agency 'Stop Dengue' website
Dengue prevention website group

Eligibility Criteria

Age21 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Adult who is visiting Sengkang Polyclinic.
  • Able to understand English.
  • Has a mobile phone which was compatible with the serious game and willing to download and attempt the serious game.
  • Able to complete questionnaires on the online secured platform, Form.sg.

You may not qualify if:

  • Adult who is not able to use a mobile phone due to physical or cognitive impairments.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

SingHealth Polyclinics - Sengkang

Singapore, 545025, Singapore

Location

MeSH Terms

Conditions

Dengue

Condition Hierarchy (Ancestors)

Mosquito-Borne DiseasesVector Borne DiseasesInfectionsArbovirus InfectionsVirus DiseasesFlavivirus InfectionsFlaviviridae InfectionsRNA Virus InfectionsHemorrhagic Fevers, Viral

Study Officials

  • Alon Tan

    SingHealth Polyclinics

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
Randomization sequence was prepared by the bio-statistician who was not involved in the enrollment of the participants. The outcome data was collected via a participant-administered questionnaire on an online secured platform, without contact with the study members. All data were de-identified and the statistical analysis was performed by the bio-statistician, who was blinded to group allocation, only after the completion of enrollment of all participants. The principal investigator was not involved in the enrollment or randomization process of participants in this study.
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: A randomized controlled trial was conducted among volunteer adults who were visiting a regional primary care clinic in Sengkang, Singapore. 400 participants were randomly allocated to receive information regarding dengue prevention from either playing a serious game (intervention) or visiting a dengue prevention website (control). Before and after receiving information on dengue prevention, participants completed a self-administered questionnaire within a 2-week interval to assess the knowledge, attitude and practice (KAP) score and their interest to vaccinate against dengue. Participants, who played serious game, evaluated the game with the Systems Usability Score (SUS).
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 18, 2022

First Posted

April 1, 2022

Study Start

March 3, 2021

Primary Completion

September 17, 2021

Study Completion

September 17, 2021

Last Updated

April 1, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations