NCT05299541

Brief Summary

Background: Many malnourished hospital patients remain after discharge. We aimed to enhance the meal experience after discharge by delivering meals together with physical support at the home and tested if this increased food intake affected survival and quality of life. Patients and Methods: 60 discharged patients suffering from nutritional (MUST\>2) and financial frailty were included. Control group (C) took their regular nutrition at home for 6 months and study group (S) received a daily dinner tray sponsored by the municipality. Hazalla philanthropic organization encouraged the patients at lunch for 6 months. Body composition (Quadstat 4000, Bodystat, UK), energy requirements (Fitmate- COSMED, Italy) were measured at recruitement. Primary outcome was 180 days survival. In addition, in the recruitment stage and after a period of 3 and 6 months, depression and anxiety questionnaire (HADS), quality of Life Questionnaire-SF36and FIM questionnaire - designed to examine the level of independence of patients with disability were performed at days 0, 90 and 180. Statistical analysis used T- Test and ANOVA Repeated Measures. The study was approved by local IRB.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 2, 2017

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 6, 2020

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 11, 2021

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

February 14, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

March 29, 2022

Completed
Last Updated

March 29, 2022

Status Verified

March 1, 2022

Enrollment Period

3.3 years

First QC Date

February 14, 2022

Last Update Submit

March 28, 2022

Conditions

Outcome Measures

Primary Outcomes (5)

  • Improve quality of life

    HADS questionnaire (hospital anxiety ans depression scale), scale 0-21. 0-7: normal; 8-10: borderline; 11-21: abnormal.

    6 months

  • Improve quality of life

    FIM questionnaire (functional indepence measure) scale 0 to 7, 1= total asistance, 7=complete independence, the highst score the best.

    6 months

  • Improve quality of life

    sf-36 questionnaire (short form health survey), scale 0-100, the highest the score the less disability

    6 months

  • changed Mortality

    six mounth follow up through ATD (American Trans Data Corp)

    6 months

  • changed financials costs per patient in health system

    follow up through electronic medical records

    6 months

Study Arms (3)

Control

ACTIVE COMPARATOR

Measurements and questioners

Diagnostic Test: Indirect calorimetricDiagnostic Test: BioimpedanceBehavioral: Questioners

Group A

ACTIVE COMPARATOR

Receiving Food dish every night for 6 months Measurements and questioners

Dietary Supplement: Food dishDiagnostic Test: Indirect calorimetricDiagnostic Test: BioimpedanceBehavioral: Questioners

Group B

ACTIVE COMPARATOR

Receiving Food dish every night for 6 months, at this group extra attention have given to the dish plating and appearance by professional (BOCUSE), Measurements and questioners

Diagnostic Test: Indirect calorimetricDiagnostic Test: BioimpedanceBehavioral: QuestionersDietary Supplement: Plated food dish

Interventions

Food dishDIETARY_SUPPLEMENT

All patients will be assessed for nutritional risk estimates (MUST) as well as a nutritional PANDORA estimate that predicts mortality, the Pandora estimate will be measured even after 3 and 6 months Group A - will receive a dish of food every evening by a person employed by a rescue organization for 6 months At the end of the meal once a week * All dishes will be photographed at the end of the meal by Android camera, iPhone * A NUTRITION DAY success photo form will be completed and collected .

Group A
Indirect calorimetricDIAGNOSTIC_TEST

• The patient will be measured with an indirect calorimetry device (Fitmate - COSMED Srl. Rome, Italy) to assess the nutritional requirement.

ControlGroup AGroup B
BioimpedanceDIAGNOSTIC_TEST

• The body composition test will be performed by the Bodystat®4000 Bioimpedance Device (BIA 4000, Bodystat, UK). .

ControlGroup AGroup B
QuestionersBEHAVIORAL

At 3 times point , in the recruit + 3 month and 6 month 3 questioners will be given: HADS, Quality of life 36SF and FIM

ControlGroup AGroup B
Plated food dishDIETARY_SUPPLEMENT

All patients will be assessed for nutritional risk estimates (MUST) as well as a nutritional PANDORA estimate that predicts mortality, the Pandora estimate will be measured even after 3 and 6 months Group b - will receive a food dish every evening by a person employed by a rescue organization with improved appearance of a plate for 6 months. At the end of the meal once a week * All dishes will be photographed at the end of the meal by Android camera, iPhone * A NUTRITION DAY success photo form will be completed and collected .

Group B

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • MUST =\>2
  • Region of living Bney-Brak or Petah-tikwa
  • Fine cognitive state

You may not qualify if:

  • Progressive cancer
  • Dementia
  • Fiddling by PEG or Enteral nutrient via Naso gastric tube
  • Psychiatrics disorder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Rabin medical center

Petah Tikva, Israel

Location

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic Diseases

Study Officials

  • Pierre Singer, Prof

    Rabin Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
ICU Manager

Study Record Dates

First Submitted

February 14, 2022

First Posted

March 29, 2022

Study Start

April 2, 2017

Primary Completion

August 6, 2020

Study Completion

January 11, 2021

Last Updated

March 29, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations