NCT03569982

Brief Summary

MOHS method is an effective surgical technique to remove skin cancerous tumors in the head-neck area. Patients undergoing MOHS surgery are struggled with emotional stress during the day of surgery, due to fear of significant damage to the body's image and anxiety about the need for repeated surgeries. In this study we will examine the effect of integrative medicine (including acupuncture, touch/manual, and breathing/relaxation modalities) on the reduction of anxiety and pain in patients undergoing MOHS surgery.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
44

participants targeted

Target at P25-P50 for not_applicable quality-of-life

Timeline
Completed

Started Nov 2018

Longer than P75 for not_applicable quality-of-life

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 2, 2018

Completed
2 months until next milestone

First Posted

Study publicly available on registry

June 26, 2018

Completed
5 months until next milestone

Study Start

First participant enrolled

November 8, 2018

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 20, 2022

Completed
Last Updated

March 22, 2022

Status Verified

March 1, 2022

Enrollment Period

3.1 years

First QC Date

May 2, 2018

Last Update Submit

March 20, 2022

Conditions

Keywords

Integrative medicinePeri-operative anxietyPainMOHS surgery

Outcome Measures

Primary Outcomes (1)

  • Anxiety as assessed by State-Trait Anxiety Inventory

    Alleviating anxiety throughout MOHS surgery

    8 hours

Secondary Outcomes (2)

  • Heart rate variability (HRV)

    30 minutes

  • Pain as assessed by visual analogue scale

    60 minutes

Study Arms (2)

Control

NO INTERVENTION

Patients receiving best supportive care

Intervention

EXPERIMENTAL

Patients receiving integrative care (including acupuncture) in addition to best supportive care

Other: Integrative medicine care

Interventions

Including acupuncture, relaxation/breathing, and manual/touch modalities

Intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \* Patients referred to MOHS surgery

You may not qualify if:

  • Pregnancy
  • Hypertension treated with alpha and beta-blockers
  • Chronic atrial fibrillation
  • insulin dependent diabetes type 1
  • Thyroid disease (hyperthyroidism)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Lin Medical Center

Haifa, Israel

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Masking Details
Patients will be referred by the surgeon to MOHS surgery without knowing if integrative care will be provided at the surgery day. Allocation of integrative care to specific surgery days will be determined by a 1:1 randomization.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: Prospective randomized controlled
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical associate professor

Study Record Dates

First Submitted

May 2, 2018

First Posted

June 26, 2018

Study Start

November 8, 2018

Primary Completion

December 1, 2021

Study Completion

March 20, 2022

Last Updated

March 22, 2022

Record last verified: 2022-03

Locations