The Relationship Between Disease Severity and Various Lower Extremity Parameters in Individuals With Knee Osteoarthritis

NCT05294224 | Completed

• 1 other identifier: 210077/10
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study perform to investigate the relationship between quadriceps femoris (QF) strength, QF thickness, femoral cartilage thickness, knee function, balance, kinesiophobia and gait of the patients with knee osteoarthritis.

Conditions

Knee Osteoarthritis; Knee Injuries

Keywords

muscle thikness; cartilage thickness; balance; postural stability; kinesiophobia; gait; degeneration; function

Outcome Measures

Primary Outcomes (8)

• QF muscle thickness

  QF muscle thickness

  Day 1

• QF muscle strength

  QF muscle strength

  Day 1

• Femoral cartilage thickness

  Femoral cartilage thickness

  Day 1

• Knee function

  Knee function assessment with The Knee injury and Osteoarthritis Outcome Score (KOOS). It is a 42-item questionnaire, including 5 subscales: symptoms, pain, ADLs, sports/recreation, and quality of life. The maximum score a patient can achieve is 100, indicating no knee problems. The minimum score is zero, indicating severe knee problems.

  Day 1

• Kellgreen-Lawrence Radiological Stages

  Kellgreen-Lawrence Radiological Stages: Grade 1 (doubtful): doubtful joint space narrowing and possible osteophytic lipping. grade 2 (minimal): definite osteophytes and possible joint space narrowing. grade 3 (moderate): moderate multiple osteophytes, definite narrowing of joint space and some sclerosis and possible deformity of bone ends.

  Day 1

• Kinesiophobia

  Tampa Kinesiophobia Scale: The total score of the scale range from 17- 68, where 17 means no kinesiophobia, 68 means severe kinesiophobia, and score ± 37 indicates there is kinesiophobia.

  Day 1

• Balance and gait

  Tinetti Score: It uses a 3-point ordinal scale of 0, 1 and 2. Gait is scored over 12 and balance is scored over 16 totalling 28. The lower the score on the Tinetti test, the higher the risk of falling.

  Day 1

• Low Extremity Functionality and Fall Risk

  30 sec sit to stand test

  Day 1

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Volunteer patients who applied to the Physical therapy and Rehabilitation department with knee pain

You may qualify if:

• Volunteer patients who applied to the Physical therapy and Rehabilitation department with knee pain

You may not qualify if:

• Individuals who have received intra-articular therapy for gonarthrosis in the last 6 months, who have undergone arthroscopic surgery, and who have additional pathologies in their lower extremities
• Individuals with physical, mental and/or psychological disorders that may affect participation in the study

Sponsors & Collaborators

• Dilara Özen Oruk: lead
• Muğla Sıtkı Koçman University: collaborator

Study Sites (1)

Mugla Sıtkı Koçman University

Muğla, 48000, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, Knee; Knee Injuries; Kinesiophobia

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Leg Injuries; Wounds and Injuries; Phobic Disorders; Anxiety Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: March 15, 2022
• First Posted: March 24, 2022
• Study Start: April 17, 2022
• Primary Completion: August 30, 2022
• Study Completion: September 30, 2023
• Last Updated: March 15, 2024

Record last verified: 2024-03

Locations

TU (1)