Neuromuscular Training Program in Patients With Knee OA (Osteoarthritis)

NCT06270329 | Completed DMC

• 1 other identifier: NMTwithKOA
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare the effects of neuromuscular training program and conventional physical therapy program on pain, functional status, physical performance, balance, muscle strength and quality of life in patients with knee osteoarthritis (KOA).

Conditions

Knee Osteoarthritis

Keywords

Neuromuscular training; Knee osteoarthritis; Physical therapy

Outcome Measures

Primary Outcomes (6)

• Visual Analog Scale

  Pain evaluation. The participant is asked to give a score between 1 and 10 for her pain.

  At first and third week

• Western Ontario and McMasterUniversities Osteoarhritis Index

  Functional status evaluation. The scale consists of 3 subheadings that evaluate pain, stiffness and physical function. High Western Ontario and McMasterUniversities Osteoarhritis Index score indicates increased pain and stiffness and deterioration in physical function.

  At first and third week

• Time on One Leg Standing

  Balance evaluation. Participants were asked to stand on one leg with their eyes open for as long as possible, and the time was measured with a stopwatch and recorded in seconds.

  At first and third week

• Five Times Sit to Stand Test

  Physical performance evaluation. The time it takes for the patient to sit and stand up from a chair five times is recorded. As time decreases, it indicates better performance.

  At first and third week

• Manual Muscle Test

  Muscle strength evaluation. A score between 0 and 5 is given depending on muscle strength.

  At first and third week

• Short Form

  Quality of life evaluation. It consists of 8 subheadings: physical function, problems caused by physical problems, emotional well-being, problems caused by emotional problems, general health, social function, pain, energy/fatigue. High scores indicate good health, low scores indicate poor health.

  At first and third week

Study Arms (2)

neuromuscular training program

EXPERIMENTAL

Participants were administered the neuromuscular training program 60 min a day, 2 days a week for 8 weeks.

Other: Neuromuscular training program

conventional physical therapy program

ACTIVE COMPARATOR

Participants were administered the conventional physiotherapy program 60 min a day, 2 days a week for 8 weeks.

Other: conventional physical therapy program

Interventions

Neuromuscular training program OTHER

Hotpack application TENS (transcutaneous electrical stimulation) Warm-up phase: bicycle ergometer (ten minutes) Exercise phase: core stabilization and postural control exercises postural orientation exercises lower extremity strengthening exercises functional exercises (balance and proprioception exercises using a balance board) Cool-down Phase

neuromuscular training program

conventional physical therapy program OTHER

Hotpack application TENS (transcutaneous electrical stimulation) Conventional physical therapy exercises (straight leg raises, knee flexor and extensor strengthening, hip muscle strengthening)

conventional physical therapy program

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Having grade 2 or 3 osteoarthritis according to the Kellgren and Lawrence Classification
• Having pain score of 2 or above on VAS
• Not having received physical therapy in the last 3 months
• Not having received an intra-articular corticosteroid injection in the last 6 months
• Not having used oral corticosteroids in the last month
• Being between the ages of 40-80
• Body mass index being between 19-40 kg/cm2

You may not qualify if:

• Systemic arthritis
• Hypertensive condition that prevents exercise
• Pregnancy, cognitive impairment, parkinson-like neurological disorders
• Having had a knee or hip joint replacement

Sponsors & Collaborators

• Kutahya Health Sciences University: lead

Study Sites (1)

Kutahya Health Science University

Kütahya, 43100, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof.

Model Details: randomized controlled clinical trial design

Study Record Dates

• First Submitted: February 10, 2024
• First Posted: February 21, 2024
• Study Start: January 15, 2022
• Primary Completion: January 15, 2023
• Study Completion: June 15, 2023
• Last Updated: February 21, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)