Implicit Learning in Epileptic Children

NCT05285059 | Recruiting

• 1 other identifier: 69HCL21_1190
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 3

Brief Summary

Epileptic children suffer from impairments in various learning and memory tasks. Yet, no study investigated implicit learning in epileptic children. Implicit learning is not only underlying motor skills acquisition, but also social and cognitive ones. Because acquisition of new skills is optimal during childhood, the study of implicit learning mechanism in children is of major importance. The present study will be the first to explore implicit learning mechanisms in children with epilepsy. Implicit learning mechanisms can be preserved or altered.

Conditions

Epilepsy

Keywords

Epilepsy,; children,; implicit learning

Outcome Measures

Primary Outcomes (2)

• Response time

  Response time (in milliseconds) recorded during the ASRT task

  The day of the inclusion

• Response accuracy recorded during the ASRT task

  Response accuracy (percentage of correct answers)

  The day of the inclusion

Study Arms (2)

Patients

8- to 14-years-old children with epilepsy

Behavioral: ASRT task

Control

8- to 14-years-old children without neurological, psychiatric, or developmental impairments

Behavioral: ASRT task

Interventions

ASRT task BEHAVIORAL

The ASRT (Alternating Serial Reaction Time) task is a computerized behavioral task measuring implicit learning. This task consists of 20 series of trials lasting 2 minutes each. In each trial, a stimulus is displayed on the screen in one of the four possible predefined locations. The participant must press a button to indicate the position of the stimulus on the screen. Response content and response time are recorded. At the end of every trial, the participant can take a break and resume the task whenever ready. The task lasts about 45 to 50 minutes.

Control; Patients

Eligibility Criteria

• Age: 8 Years - 14 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

This study focuses on children with epilepsy.

You may qualify if:

• For Patient group only: Children with epilepsy
• For Control group only: Children without neurological, psychiatric or developmental impairments
• For both groups: Parent or tutors agreement
• For both groups: Affiliated to French social security

You may not qualify if:

• Neurological impairments unrelated to epilepsy
• Psychiatric impairments unrelated to epilepsy
• Developmental impairments unrelated to epilepsy

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (3)

Agathe Marcastel, PhD

Bron, Bron, 69675, France

RECRUITING

Dezso Nemeth

Bron, Bron, 69675, France

NOT YET RECRUITING

Service d'Epileptologie Clinique, des Troubles du sommeil et de Neurologie fonctionnelle de l'enfant, à Hôpital Femme Mère et Enfant,

Bron, France

RECRUITING

MeSH Terms

Conditions

Epilepsy

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Marcastel Agathe, PhD

  Service d'Epileptologie Clinique, des Troubles du sommeil et de Neurologie fonctionnelle de l'enfant - Hôpital Femme Mère Enfant

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Marcastel Agathe, PhD

CONTACT

+33 4 27 85 60 40; Agathe.marcastel@chu-lyon.fr

Nemeth Dezso, Pr

CONTACT

+33 4 81 10 66 04; dezso.nemeth@univ-lyon1.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2022
• First Posted: March 17, 2022
• Study Start: March 21, 2023
• Primary Completion (Estimated): March 21, 2027
• Study Completion (Estimated): March 21, 2027
• Last Updated: May 7, 2026

Record last verified: 2026-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (3)