Automated Quantification of Radiologic Pulmonary Alteration During Acute Respiratory Failure: Application to the COVID-19 Pandemic
QUANTICO-PRO
1 other identifier
interventional
500
1 country
2
Brief Summary
Automated quantification of the pulmonary volume impaired during acute respiratory failure could be helpful to assess patient severity during COVID-19 infection or perioperative medicine, for example. This study aims at assessing the correlation between the amount of radiologic pulmonary alteration and the clinical severity in two clinical situation :
- 1.SARS-CoV-2 infections
- 2.Postoperative hypoxemic acute respiratory failure.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jun 2022
Typical duration for not_applicable
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
March 11, 2022
CompletedFirst Posted
Study publicly available on registry
March 14, 2022
CompletedStudy Start
First participant enrolled
June 13, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2025
CompletedJune 30, 2022
June 1, 2022
2.8 years
March 11, 2022
June 23, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Correlation between altered pulmonary volume and ordinal severity scale
This criterion will be expressed as a score between 1 (least severe) and 7 (most severe).
2 days after CT scan (Day 2)
Secondary Outcomes (4)
Correlation between altered pulmonary volume and ordinal severity scale
7 days after CT scan (Day 7)
Mortality
90 days following CT scan (Day 90)
Rate of admission to intensive care unit
28 days following CT scan (Day 28)
Initial length of hospitalization stay (in days)
90 days following CT scan (Day 90)
Study Arms (1)
Thoracic CT Scan
EXPERIMENTALInterventions
Automated quantitative analysis of altered pulmonary volume
Eligibility Criteria
You may qualify if:
- Subject admitted to a care unit of the University Hospitals of Strasbourg or the University Hospital of Nancy and presenting a suspicion of SARS-CoV-2 infection or postoperative hypoxemic respiratory failure
- Able to understand the objectives and risks of the research and to give dated and signed informed consent.
- Subjects may also be included in emergency or immediate life-threatening situations.
- Subject with insurance covering
You may not qualify if:
- Pregnant woman (pregnancy confirmed by a urine or blood test)
- Subject usually on home oxygen therapy
- Subject under court protection
- Subject under guardianship or curatorship
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University Hospital, Strasbourg, Francelead
- REGION GRAND ESTcollaborator
- E-MEDIAcollaborator
- VISIBLE PATIENTcollaborator
Study Sites (2)
Service d'anesthésie réanimation-CHU de Nancy
Nancy, 54500, France
Service d'Anesthésie-Réanimation - CHU Strasbourg
Strasbourg, 67098, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 11, 2022
First Posted
March 14, 2022
Study Start
June 13, 2022
Primary Completion
April 1, 2025
Study Completion
June 1, 2025
Last Updated
June 30, 2022
Record last verified: 2022-06
Data Sharing
- IPD Sharing
- Will not share