NCT04534400

Brief Summary

Automated quantification of the pulmonary volume impaired during acute respiratory failure could be helpful to assess patient severity during COVID-19 infection or perioperative medicine, for example. This study aim at assessing the correlation between the amount of radiologic pulmonary alteration and the clinical severity in two clinical situation :

  1. 1.SARS-CoV-2 infections
  2. 2.Postoperative hypoxemic acute respiratory failure

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Sep 2020

Typical duration for all trials

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 26, 2020

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 1, 2020

Completed
Same day until next milestone

Study Start

First participant enrolled

September 1, 2020

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2024

Completed
Last Updated

April 18, 2023

Status Verified

April 1, 2023

Enrollment Period

3.5 years

First QC Date

August 26, 2020

Last Update Submit

April 14, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Correlation between altered pulmonary volume and ordinal severity scale

    2 days after CT scan

Secondary Outcomes (1)

  • Correlation between altered pulmonary volume and ordinal severity scale

    7 days after CT scan

Study Arms (2)

Patients with SARS-CoV-2 infection

Radiation: thoracic CT-scan

Patients with Postoperative hypoxemic respiratory failure

Radiation: thoracic CT-scan

Interventions

Automated measurement

Patients with Postoperative hypoxemic respiratory failurePatients with SARS-CoV-2 infection

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Hospitalized patients that underwent a thoracic CT-scan

You may qualify if:

  • patient with insurance covering
  • patient admitted to the participating hospitals for SARS-CoV-2 infection or postoperative acute hypoxemic respiratory failure between 01/01/2019 and 05/11/2020

You may not qualify if:

  • \- patient transferred to another hospital than the participating center during the 7 days following the CT scan

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

HÔPITAUX UNIVERSITAIRES DE STRASBOURG, Hôpital de Hautepierre, Service de Réanimation Médicale

Strasbourg, 67098, France

RECRUITING

Hôpitaux Universitaires de Nancy Service d'anesthésie réanimation Hôpital de Brabois

Vandœuvre-lès-Nancy, 54500, France

NOT YET RECRUITING

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2020

First Posted

September 1, 2020

Study Start

September 1, 2020

Primary Completion

March 1, 2024

Study Completion

March 1, 2024

Last Updated

April 18, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations