NCT05270707

Brief Summary

The HyperArc registry is designed to collect data from which the efficacy of the HyperArc procedure can be assessed and compared to alternative treatments.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
968

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2022

Typical duration for all trials

Geographic Reach
4 countries

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 14, 2022

Completed
22 days until next milestone

First Posted

Study publicly available on registry

March 8, 2022

Completed
23 days until next milestone

Study Start

First participant enrolled

March 31, 2022

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2025

Completed
Last Updated

September 24, 2025

Status Verified

September 1, 2025

Enrollment Period

3 years

First QC Date

February 14, 2022

Last Update Submit

September 19, 2025

Conditions

Brain MetastasesCNS NeoplasmCNS Disorder, Intracranial

Keywords

Stereotactic Radiosurgery

Outcome Measures

Primary Outcomes (1)

  • Survival

    Survival

    follow until death, on average approximately 2 years

Secondary Outcomes (2)

  • Local tumor control

    follow until death, on average approximately 2 years

  • HyperArc Patterns of Care

    Limited to course of treatment: up to 4 weeks

Interventions

Stereotactic radiosurgeryRADIATION

HyperArc is a radiotherapy treatment with a structured workflow to plan and deliver stereotactic radiosurgery (SRS).

Also known as: HyperArc SRS

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Any patient scheduled to be treated using the HyperArc method will be invited to participate, provided they meet other eligibility criteria.

You may qualify if:

  • Received or scheduled to receive treatment using the HyperArc treatment method
  • Age of legal adult according to local law
  • Signed informed consent form, or, informed consent waived by the local ethics board/institutional review board

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

University of Alabama

Birmingham, Alabama, 35233, United States

Location

Icon Cancer Centre Canberra

Bruce, Australian Capital Territory, 2617, Australia

Location

Icon Cancer Centre Greenslopes

Greenslopes, Queensland, 4120, Australia

Location

Icon Cancer Centre Maroochydore

Maroochydore, Queensland, 4558, Australia

Location

Icon Cancer Centre Gold Coast Private

Southport, Queensland, 4215, Australia

Location

University Hospital Leuven

Leuven, 3000, Belgium

Location

L'IRCCS Ospedale Sacro Cuore - Don Calabria

Negrar, Valpolicella, 37024, Italy

Location

MeSH Terms

Conditions

Brain NeoplasmsCentral Nervous System NeoplasmsBrain Diseases

Interventions

Radiosurgery

Condition Hierarchy (Ancestors)

Nervous System NeoplasmsNeoplasms by SiteNeoplasmsCentral Nervous System DiseasesNervous System Diseases

Intervention Hierarchy (Ancestors)

RadiotherapyTherapeuticsStereotaxic TechniquesNeurosurgical ProceduresSurgical Procedures, OperativeInvestigative Techniques

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
OTHER
Target Duration
1 Year
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 14, 2022

First Posted

March 8, 2022

Study Start

March 31, 2022

Primary Completion

March 31, 2025

Study Completion

March 31, 2025

Last Updated

September 24, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations

AU(4)IT(1)US(1)BE(1)