Brain Metastases
342
79
109
92
Key Insights
Highlights
Success Rate
72% trial completion
Published Results
34 trials with published results (10%)
Research Maturity
92 completed trials (27% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 72/100
10.2%
35 terminated out of 342 trials
72.4%
-14.1% vs benchmark
7%
24 trials in Phase 3/4
37%
34 of 92 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 92 completed trials
Clinical Trials (342)
IL-8 Receptor Modified Patient-Derived Activated CD70 CAR T Cell Therapy in Adults With Brain Metastases
MRI Following Stereotactic Radiosurgery (SRS) for Brain Metastases
ioMRI in the Surgery of Brain Metastases.
Supportive Care With or Without Repeated Whole Brain Radiotherapy in Patients With Recurrent Brain Metastases
Neoadjuvant vs. Intraoperative vs. Adjuvant Resection Cavity Radiotherapy of Brain Metastases
Development of MRF for Characterization of Brain Tumors After Radiotherapy
Measuring and Mapping Cognitive Decline After Brain Radiosurgery
Optimizing Neurocognition With Whole Brain Radiation Therapy (WBRT) Using Upfront Pulsed Reduced Dose-Rate (PRDR) Technique
Brain Radiotherapy Combined With Dalpiciclib and Endocrine Therapy in HR-Positive/HER2-Negative Advanced Breast Cancer With Brain Metastases
Radiosurgery With or Without Whole Brain Radiation for Multiple Metastases
Assess Use of 18F-Fluciclovine for Patients With Large Brain Metastases Treated With Staged Stereotactic Radiosurgery
GDC-0084 With Radiation Therapy for People With PIK3CA-Mutated Solid Tumor Brain Metastases or Leptomeningeal Metastases
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
Inflammation in Primary and Secondary Malignancies of the Central Nervous System Using [C-11]-CS1P1
Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors
NTS-WBRT in Brain Metastases
Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases
A Pilot Study to Assess the Clinical Utility of 18F-Fluciclovine (Axumin) PET-CT for Detecting True-versus Pseudo-Progression of Brain Metastases on Immunotherapy
EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active
Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases